Jun Zhang

ORCID: 0000-0003-1706-1611
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About
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Research Areas
  • Birth, Development, and Health
  • Pregnancy and preeclampsia studies
  • Gestational Diabetes Research and Management
  • Maternal and Perinatal Health Interventions
  • Per- and polyfluoroalkyl substances research
  • Air Quality and Health Impacts
  • Assisted Reproductive Technology and Twin Pregnancy
  • Maternal and fetal healthcare
  • Global Maternal and Child Health
  • Neonatal Respiratory Health Research
  • Effects and risks of endocrine disrupting chemicals
  • Pregnancy-related medical research
  • Climate Change and Health Impacts
  • Preterm Birth and Chorioamnionitis
  • Pregnancy and Medication Impact
  • Toxic Organic Pollutants Impact
  • Obesity, Physical Activity, Diet
  • Maternal Mental Health During Pregnancy and Postpartum
  • Asthma and respiratory diseases
  • Heavy Metal Exposure and Toxicity
  • Pelvic floor disorders treatments
  • Reproductive System and Pregnancy
  • Ovarian function and disorders
  • Gut microbiota and health
  • Breastfeeding Practices and Influences

XinHua Hospital
2016-2025

Shanghai Jiao Tong University
2016-2025

International Peace Maternity & Child Health Hospital
2015-2025

Xiamen University
2019-2025

Farmland Irrigation Research Institute
2024

Nanjing University
2024

Nanjing General Hospital of Nanjing Military Command
2024

Shihezi University
2024

Xi'an Jiaotong University
2021-2024

Fudan University
2016-2024

In response to the coronavirus disease 2019 (COVID-19) outbreak, Chinese Government has ordered a nationwide school closure as an emergency measure prevent spreading of infection. Public activities are discouraged. The Ministry Education estimates that more than 220 million children and adolescents confined their homes; this includes 180 primary secondary students 47 preschool children).1CCTV NewsMinistry Education: national elementary middle network cloud platform opens for free use...

10.1016/s0140-6736(20)30547-x article EN other-oa The Lancet 2020-03-01

Caesarean section (CS) rates continue to evoke worldwide concern because of their steady increase, lack consensus on the appropriate CS rate and associated additional short- long-term risks costs. We present latest trends over last 24 years.

10.1371/journal.pone.0148343 article EN cc-by PLoS ONE 2016-02-05

Bilirubin clearance is one of the numerous important functions liver. Defects in this process result jaundice, which particularly common neonates. Elevated bilirubin levels can be decreased by treatment with phenobarbital. Because nuclear hormone receptor constitutive androstane (CAR) mediates hepatic effects xenobiotic inducer, we hypothesized that CAR could a regulator clearance. Activation increases expression each five components bilirubin-clearance pathway. This induction absent...

10.1073/pnas.0630614100 article EN Proceedings of the National Academy of Sciences 2003-03-18

Caesarean section was initially performed to save the lives of mother and/or her baby. rates have risen substantially worldwide over past decades. In this study, we set out compile all available caesarean at country level, and identify appropriate rate population level associated with minimal maternal neonatal mortality.Ecological study using longitudinal data.Worldwide country-level data.A total 159 countries were included in analyses, representing 98.0% global live births (2005).Nationally...

10.1111/1471-0528.13592 article EN cc-by-nc BJOG An International Journal of Obstetrics & Gynaecology 2015-08-24

Over the past three decades, World Health Organization expert panel proposed cesarean delivery rate of 10-15 percent was used as a doctrine for an optimal despite lack concrete evidence. We set out to compile rates, socioeconomic indicators, and health outcomes by countries in last decades explore rates medically necessary delivery.We selected 19 which have readily accessible low maternal infant mortality, including North West Europe, America, Australia, New Zealand, Japan. Information on...

10.1111/birt.12104 article EN Birth 2014-04-11

<h3>Importance</h3> Preeclampsia is a leading cause of maternal and perinatal morbidity mortality worldwide. Within-country studies have reported racial differences in the presentation outcome, but little known about between countries. <h3>Objective</h3> To compare preeclampsia prevalence, risk factors, pregnancy outcomes Swedish Chinese populations. <h3>Design, Setting, Participants</h3> This cross-sectional study compared deliveries from national Medical Birth Register (2007-2012) China...

10.1001/jamanetworkopen.2021.8401 article EN cc-by-nc-nd JAMA Network Open 2021-05-10

Few studies have assessed the relationship between multimorbidity patterns and mortality risk in Chinese population. We aimed to identify examined associations of number chronic diseases with among middle-aged older adults.We used data from China Kadoorie Biobank included 512,723 participants aged 30 79 years. Multimorbidity was defined as presence two or more 15 collected by self-report physical examination at baseline. were identified using hierarchical cluster analysis. Cox regression...

10.1097/cm9.0000000000001985 article EN cc-by-nc-nd Chinese Medical Journal 2022-02-21

This study was to report the incidence of severe maternal morbidity associated with hypertensive disorders pregnancy in United States.We used data from National Hospital Discharge Survey, a nationally representative sample discharge records, 1988 1997. The database consisted approximately 300,000 deliveries, which represented 39 million births during 10-year period.The overall 5.9% [95% confidence interval (CI): 5.2 6.5%]. Eclampsia reported at 1.0 per 1,000 deliveries (95% CI: 0.8 1.2)....

10.1081/prg-120021066 article EN Hypertension in Pregnancy 2003-01-01

In Brief OBJECTIVE: To examine the effect of maternal overweight and obesity on labor progression. METHODS: We analyzed data from 612 nulliparous women with a term pregnancy that participated in Pregnancy, Infection, Nutrition Study 1995 to 2002. The median duration by each centimeter cervical dilation was computed for normal-weight (body mass index [BMI] 19.8–26.0 kg/m2), (BMI 26.1–29.0 obese > 29.0 kg/m2) used as measurement RESULTS: After adjusting height, induction, membrane rupture,...

10.1097/01.aog.0000142713.53197.91 article EN Obstetrics and Gynecology 2004-11-01

10.1067/mob.2002.127142 article EN American Journal of Obstetrics and Gynecology 2002-10-01

Misoprostol is increasingly used to treat women who have a failed pregnancy in the first trimester. We assessed efficacy, safety, and acceptability of this treatment large, randomized trial.A total 652 with first-trimester failure (anembryonic gestation, embryonic or fetal death, incomplete inevitable spontaneous abortion) were randomly assigned receive 800 microg misoprostol vaginally undergo vacuum aspiration (standard care) 3:1 ratio. The group received on day 1, second dose 3 if...

10.1056/nejmoa044064 article EN New England Journal of Medicine 2005-08-24

Yin Zhi Huang, a decoction of Chin (Artemisia capillaris) and three other herbs, is widely used in Asia to prevent treat neonatal jaundice. We recently identified the constitutive androstane receptor (CAR, NR1I3) as key regulator bilirubin clearance liver. Here we show that treatment WT humanized CAR transgenic mice with Huang for 3 days accelerates intravenously infused bilirubin. This effect absent knockout animals. Expression glucuronyl transferase components metabolism pathway induced by...

10.1172/jci18385 article EN Journal of Clinical Investigation 2004-01-01

Yin Zhi Huang, a decoction of Chin (Artemisia capillaris) and three other herbs, is widely used in Asia to prevent treat neonatal jaundice. We recently identified the constitutive androstane receptor (CAR, NR1I3) as key regulator bilirubin clearance liver. Here we show that treatment WT humanized CAR transgenic mice with Huang for 3 days accelerates intravenously infused bilirubin. This effect absent knockout animals. Expression glucuronyl transferase components metabolism pathway induced by...

10.1172/jci200418385 article EN Journal of Clinical Investigation 2004-01-01

To estimate the incidence of overall cesarean delivery and on maternal request in southeast China past decade.We used data from a population-based child health surveillance system, which covers 21 cities counties two provinces China. We examined rate 1.1 million singleton births 1994 to early 2006. Cesarean was defined as prelabor for gestation without contraindications vaginal at 38 weeks or later.During 13-year study period, percentage women who had high school higher education increased...

10.1097/aog.0b013e31816e349e article EN Obstetrics and Gynecology 2008-05-01

To characterize potentially modifiable risk factors for third- or fourth-degree perineal lacerations and cervical in a contemporary U.S. obstetric practice.The Consortium on Safe Labor collected electronic medical records from 19 hospitals within 12 institutions (228,668 deliveries 2002 to 2008). Information patient characteristics, prenatal complications, labor delivery data, maternal neonatal outcomes were collected. Only women with successful vaginal of cephalic singletons at 34 weeks...

10.1097/aog.0b013e31820afaf2 article EN Obstetrics and Gynecology 2011-02-23
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