A5083720986- Monoclonal and Polyclonal Antibodies Research
- Musculoskeletal synovial abnormalities and treatments
- Rheumatoid Arthritis Research and Therapies
- Orthopedic Surgery and Rehabilitation
- Systemic Lupus Erythematosus Research
- Cell Adhesion Molecules Research
- Cardiac Arrest and Resuscitation
- Inflammatory Myopathies and Dermatomyositis
- Tendon Structure and Treatment
- Immunodeficiency and Autoimmune Disorders
- Orthopedic Infections and Treatments
- Shoulder Injury and Treatment
- Trace Elements in Health
- Cardiovascular Effects of Exercise
- Cardiac pacing and defibrillation studies
- Autoimmune and Inflammatory Disorders Research
- Inflammatory mediators and NSAID effects
- Virus-based gene therapy research
- Helicobacter pylori-related gastroenterology studies
- Virology and Viral Diseases
- T-cell and B-cell Immunology
- Musculoskeletal Disorders and Rehabilitation
- Hemophilia Treatment and Research
- Complement system in diseases
- Pharmacological Effects of Medicinal Plants
Capital and Coast District Health Board
2023
Christchurch Hospital
2020-2021
Wellington Hospital
1979-2020
Auckland City Hospital
1979-2020
New Zealand Brain Research Institute
2020
Aintree University Hospital
2011-2020
University of Liverpool
2011-2020
Canterbury District Health Board
2020
Dicerna Pharmaceuticals (United States)
2016
Baxalta (United States)
2016
Abstract A new monoclonal antibody (mAb), named 3.9, is described that specific for the p150,95 molecule, a member of LFA‐1, CR3, family human leukocyte differentiation antigens. The LFA‐1 molecule participates in variety T cell interactions and CR3 receptor complement component iC3b, but little known about molecule. Here we show expression confined to myeloid cells. mAb 3.9 reacts variably with neutrophils, more strongly monocytes most expressed on tissue macrophages. Using this others,...
The properties of the mononuclear phagocyte (Mph) high-affinity Fc receptor, FcRI, were investigated using a novel monoclonal antibody (mAb) designated 10.1. This receptor was shown to be protein 71 kDa, presented chiefly on monocytes and myeloid cell lines U937 HL60. mAb 10.1 inhibited binding Mph erythrocytes opsonized with rabbit IgG or human IgG3. It also blocked T proliferation induced by murine CD3 IgG2a but not IgG1 subclass. These results suggest that IgG, IgG3 all bind FcRI in...
Para-articular and extra-articular cystic swellings arising from bursae, tendon sheaths, joints in rheumatoid disease were examined by contrast radiography. The complications that may follow these lesions are discussed. relationship occult popliteal cysts have to discomfort behind the knee is noted.
Abstract Background Functional neurological disorders (FND) represent a significant proportion of presentations to outpatient adult neurology services. There is little information relating patients presenting acute inpatient care. Methods We identified as admissions with FND Christchurch Hospital, Christchurch, New Zealand, from 2016 2018. analyzed relevant demographic and clinical data electronic records measured incidence presentation secondary care healthcare utilization. Results One...
Journal Article CLINICAL AND MORPHOLOGICAL FEATURES OF GOLD NEUROPATHY Get access S. M. KATRAK, KATRAK From the Divisions of Neurology and Rheumatology, Department Medicine, University Otago Medical SchoolDunedin, New Zealand Search for other works by this author on: Oxford Academic PubMed Google Scholar POLLOCK, POLLOCK C. P. O' BRIEN, BRIEN H. NUKADA, NUKADA ALLPRESS, ALLPRESS CALDER, CALDER D. G. PALMER, PALMER GRENNAN, GRENNAN L. MCCORMACK, MCCORMACK R. LAURENT Brain, Volume 103, Issue...
Functional neurological disorder (FND) is a disabling condition which has poor prognosis without treatment. This study aimed to evaluate the effectiveness of an outpatient integrated multidisciplinary intervention for condition.
Many different techniques for ankle arthrodesis have been described. Experience at our institution with crossed screws internal fixation has not met the 90+% union rate reported in literature. A compression blade plate is one technique which evaluated biomechanically. biomechanical study comparing two groups of sawbone fusion constructs fixed and plates was performed order to evaluate stiffness rigidity these techniques. The construct demonstrated superior during dorsiflexion (p < 0.001)...
1. Joint compliance estimations were made on the knee joints of fourteen patients with rheumatoid arthritis, three osteoarthritis and healthy volunteers. 2. Diminishing values for capsular found in normal volunteers, under age thirty-five years over forty arthritis respectively. 3. In young adult volunteers average was 8·1 cubic centimetres per millimetre mercury at an intra-articular pressure 5 millimetres 0·7 centimetre 50 mercury. older disease 2·1 0·4 4. Both effects ageing appeared to...
Journal Article Total Leukocyte Enumeration in Pathologic Synovial Fluids Get access D. G. Palmer, M.D. Rheumatism Research Laboratories, Wellcome Medical Institute, University of Otago School, Dunedin, New Zealand Search for other works by this author on: Oxford Academic Google Scholar American Clinical Pathology, Volume 49, Issue 6, 1 June 1968, Pages 812–814, https://doi.org/10.1093/ajcp/49.6.812 Published: 01 1968 history Received: July 1967
Sequential nailfold capillary microscopy was carried out monthly for seven months in patients (four with scleroderma, one dermatomyositis, mixed connective tissue disease, and limited disease). Progressive enlargement of some loops observed, a number becoming obliterated, leaving avascular areas. Extravasation from capillaries usually preceded loss. These observations have shown the progressive nature abnormalities associated these disorders suggest that is result injury, rather than compensation
Abstract In long‐established rheumatoid nodules, monocytes continue to be recruited and migrate from the outer vascular zone toward palisade central necrotic area. Maturation of these cells is shown take place during tissue migration. We found that great majority express exclusive mononuclear phagocyte phenotypes. Among this population are many bear receptor for iC3b (CR3), but few C3b (CR1). HLA–D region molecule expression intense widespread.
Abstract A study has been made of some the factors involved in production joint effusions. The intra‐articular hydrostatic pressure appeared to be best measure disturbance fluid balance across damaged synovio‐capillary barrier. colloidal osmotic pressures effusion fluids were not related pressures. There was a non‐linear relationship between protein content and synovial fluids. level nature importance promoting passage from cavity. Preliminary observations indicated that it should prove...
Anti-N-methyl-D-aspartate receptor encephalitis is a recently discovered disease entity of paraneoplastic limbic encephalitis. It largely affects young women and often associated with an ovarian teratoma. serious yet treatable condition if diagnosed early. Its remedy involves immunotherapy surgical removal the teratoma ovaries. This case anti-N-methyl-D-aspartate early intervention bilateral oophorectomy, despite negative imaging evidence teratoma.A 25-year-old white woman presented...