A5010526590- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Advanced Malware Detection Techniques
- Security and Verification in Computing
- AI in cancer detection
- Digital and Cyber Forensics
- Legume Nitrogen Fixing Symbiosis
- 3D Shape Modeling and Analysis
- Nematode management and characterization studies
- Protein Structure and Dynamics
- Embedded Systems Design Techniques
- Advanced Neural Network Applications
- Medical Image Segmentation Techniques
- International Law and Aviation
- Computational Drug Discovery Methods
- Advanced X-ray and CT Imaging
- Smart Grid Security and Resilience
- Computer Graphics and Visualization Techniques
- Early Childhood Education and Development
- Bone and Joint Diseases
- Software System Performance and Reliability
- HER2/EGFR in Cancer Research
- Ferroptosis and cancer prognosis
- Single-cell and spatial transcriptomics
- Block Copolymer Self-Assembly
Florida Department of Citrus
2009-2022
University of Florida
2009-2022
FuelCell Energy (United States)
2022
Roswell Park Comprehensive Cancer Center
2020
University of Louisville
2004-2019
University of Southampton
2016-2019
University of Manchester
2016
Madigan Army Medical Center
2013
Loughborough University
2012
University of Louisville Hospital
2007
Development of coarse-grained (CG) molecular dynamics models is often a laborious process which commonly relies upon approximations to similar models, rather than systematic parametrization. PyCGTOOL automates much the construction CG via calculation both equilibrium values and force constants internal coordinates directly from atomistic simulation trajectories. The derivation bespoke parameters simulations improves quality model compared use generic derived other molecules, while automation...
The majority of patients with idiopathic pruritus ani respond favorably to conservative treatment. Moreover, response specific medical therapy is almost always favorable in certain dermatologic diseases such as psoriasis, mycotic dermatitis, and contact dermatitis. When surgery performed for anorectal disorders hemorrhoids fistulas, or potentially malignant entities extramammary Paget's disease, the accompanying invariably improves well. Only chronic intractable are included current study....
This paper examines the effectiveness of geometric feature descriptors, common in computer vision, for false positive reduction and classification lung nodules low dose CT (LDCT) scans. A data-driven nodule modeling approach creates templates types, using active appearance models (AAM); which are then used to detect candidate based on optimum similarity measured by normalized cross-correlation (NCC). Geometric descriptors (e.g., SIFT, LBP SURF) applied output detection step, order extract...
The vulnerability of industrial control systems (ICS) to electronic intrusion and malware has recently been well documented in both the technical popular press. Despite significant attention much progress over past 15 years, threats continue evolve about as fast preventive solutions. This paper reviews root causes ICS cybersecurity vulnerabilities, looks at some common defensive measures then discusses a new approach field device cybersecurity, security preprocessor. offers advanced...
1. The early signs of Paget's disease the acetabulum and femur are described. 2. pattern arthritis is presented in 199 hips which bone occurred either femur, or both bones. Distinct patterns occur with different involvement. 3. Selective narrowing medial segment joint common particularly associated pelvic disease. Why occurs here preferentially unexplained. 4. Protrusio acetabuli only 25 per cent usually when were involved. This may be due to presence simultaneously weakened coxa vara,...
Defect engineering at the surface of zinc oxide sub-5 nm nanoparticles provides a systemic nanotherapeutic with significant field efficacy against citrus HLB disease.
Abstract Laboratory experiments were conducted to study the effects of various trapping and endoparasitic nematophagous fungi (NF) isolated from Florida citrus orchards on five entomopathogenic nematode (EPN) species that show distributions across Florida's industry. Four NF (Arthrobotrys oligospora, A. dactyloides, musiformis Gamsylella gephyropaga) two (Catenaria sp. Myzocytium sp.) tested against Steinernema diaprepesi (Sd), S. glaseri (Sg), riobrave (Sr), Heterorhabditis zealandica (Hz)...
In this paper we propose an educational robotic system for teaching kids at nursery schools how to write and draw simple shapes. Our uses the humanoid robot NAO shapes appearing on a computer screen. The light polarization property fast detection of screen despite its content. We also mapping from image domain space.
Recently, several approaches for pedestrian detection have been investigated using discriminatively trained part based models with which Histogram of Oriented Gradients (HOG) showed to be a robust feature. In this paper, we propose new feature on HOG used the framework detection. Our method is computing image mixed partial derivatives redefine gradients some pixels and reweigh vote at all respect original HOG. approach was tested PASCAL2007 INRIA person dataset an outstanding performance.
In a mature fortune 500 manufacturing company, such as 3M Company, many processes and procedures for developing products have been put in place over the years. Many of these tools are very formal with focus on releasing that to be mass manufactured worldwide by thousands. Software development at has traditionally force fit into less than optimal success. This paper outlines our experience introducing Scrum technique agile software formalized environment.
This paper deals with segmentation of the lung tissues from low dose CT (LDCT) scans chest. Goal is correct as well maintaining details region in chest cavity. In particular, it essential that nodules inside lungs on boundary regions be maintained for subsequent steps aim at automatic detection and classification LDCT scanning; a step early diagnosis cancer. An approach based combination EM algorithm morphological operations presented. compared respect two other approaches are level sets...
This paper presents a new system for parallel inductive logic search pharmacophores which can potentially accelerate the chemical evaluation phase of drug design process. has been tested on Beowulf cluster and an IBM SP2 supercomputer with promising results.
Purpose – Two studies examined the relationship between employee satisfaction and customer in two service organizations.
In this, paper a new approach for lung nodules detection from LDCT scans is proposed. Intensity models of the are generated using an active appearance model formulation. Template matching used to compute similarity score between AAM template and input image. The goal maximize measure at different image pixels increase nodule detection. Conventional does not account rotation variations. Our proposed formulated as energy optimization problem that computes transformation includes rotation(s)...
Lung nodules from low dose CT (LDCT) scans may be used for early detection of lung cancer. However, these vary in size, shape, texture, location, and suffer occlusion within the tissue. This paper presents an approach segmentation detected by a prior step. First, regions around are segmented; using automatic seed point placement levels sets. The outline nodule region is further improved curvature characteristics boundary. We illustrate effectiveness this method Juxta-pleural nodules.
The quality of the lung nodule models determines success detection. This paper describes aspects our data-driven approach for modeling nodules using texture and shape properties real to form an average model template per type. ELCAP low dose CT (LDCT) scans database is used create required statistics based on modern computer vision techniques. These suit various machine learning approaches detection including Bayesian methods, SVM Neural Networks, computations may be enhanced through genetic...
This work presents a novel approach in automatic detection of the lung nodules and is compared with respect to parametric nodule models terms sensitivity specificity. A Statistical method used for generating data driven appearing low dose CT (LDCT) scans human chest. Four types common are analyzed using Procrustes based AAM create descriptive nodules. Performance new on clinical datasets significant over both The modeling also applicable classification into pathologies given database. major...
Accurate 3D modeling of the human teeth/jaw helps patients avoid discomfort mold process, and improves data accuracy for oral orthodontists dental care personnel. Since surface tooth is almost textureless, Shape from Shading (SFS) has been successfully adopted in solving this problem. In paper, we attempt to improve limitations previous reconstruction algorithms by developing a new approach shape single image shading with Two-Dimensional Principle Component Analysis (2D-PCA) priors. The...
<h3>Background</h3> General controlled nonderepressible 2 (GCN2) is a central kinase in the integrated stress response (ISR) that responds to amino acid deprivation. Cancer cells can utilize ISR for survival, but prolonged or hyperactivation of reduces proliferation and induces apoptosis. We are developing HC-7366, First-in-Class, First-in-Human GCN2 modulator activates GCN2, resulting anti-tumor activity. currently phase 1 trial (NCT05121948), has demonstrated robust efficacy multiple...