A5006628293- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Glioma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Global Cancer Incidence and Screening
- Economic and Financial Impacts of Cancer
- Gastric Cancer Management and Outcomes
- Lung Cancer Research Studies
- Pluripotent Stem Cells Research
- Respiratory Support and Mechanisms
- Cancer Immunotherapy and Biomarkers
- Anesthesia and Pain Management
- Brain Metastases and Treatment
- COVID-19 and healthcare impacts
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Epigenetics and DNA Methylation
- Genomics and Chromatin Dynamics
- Health Systems, Economic Evaluations, Quality of Life
- Chromatin Remodeling and Cancer
- MicroRNA in disease regulation
- Cancer-related gene regulation
- Cancer, Lipids, and Metabolism
- Sarcoma Diagnosis and Treatment
- Neutropenia and Cancer Infections
- Healthcare Systems and Challenges
Washington University in St. Louis
2023-2024
VA St. Louis Health Care System
2024
Case Western Reserve University
2020
University School
2020
Cleveland Clinic
2020
Center for Cancer Research
2014-2017
Massachusetts General Hospital
2014-2017
Harvard University
2014-2017
Broad Institute
2014
Surgical resection remains the preferred treatment for functionally fit patients diagnosed with early-stage non-small cell lung cancer (NSCLC). Process-based intraoperative quality metrics (QMs) are important optimizing long-term outcomes following curative-intent resection.
Medulloblastoma is the most frequent malignant pediatric brain tumor and divided into at least four subgroups known as WNT, SHH, Group 3, 4. Here, we characterized gene regulation mechanisms in aggressive subtype, 3 tumors, through genome-wide chromatin expression profiling. Our results show that active distal sites these tumors are occupied by transcription factor OTX2. Highly OTX2-bound enhancers often arranged clusters of adjacent peaks also bound NEUROD1. These responsive to OTX2 NEUROD1...
Background: Lung function is routinely assessed prior to surgical resection for non-small cell lung cancer (NSCLC). Further assessment of chronic obstructive pulmonary disease (COPD) using inhaled COPD medications determine severity, a readily available metric burden, may predict postoperative outcomes and overall survival (OS) in patients undergoing surgery. Methods: We retrospectively evaluated clinical stage I NSCLC receiving treatment within the Veterans Health Administration from...
Abstract Objective: Socioeconomic deprivation (SED) has been associated with higher lung cancer risk and mortality. However, the effects of SED on outcomes in an integrated, single-payer healthcare system, such as Veterans Health Administration (VHA), remains unknown. We sought to examine impact area-level access care veterans early-stage non-small cell (NSCLC). Methods: conducted a retrospective cohort study patients clinical stage I NSCLC receiving definitive surgical treatment VHA from...
Currently, there is no consensus on how to comprehensively assess comorbidities in lung cancer patients the clinical setting. Prescription medications may be a preferred comorbidity assessment tool and provide simple mechanism for predicting postoperative outcomes cancer. We examined relationship between prescription early-stage non-small cell (NSCLC).
: Socioeconomic deprivation has been associated with higher lung cancer risk and mortality in non-Veteran populations. However, the impact of socioeconomic on outcomes for non-small cell (NSCLC) an integrated equal-access healthcare system, such as Veterans Health Administration (VHA), remains unclear. Hence, we investigated area-level access to care postoperative early-stage NSCLC United States Veterans.