A5033203504- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Retinopathy of Prematurity Studies
- Retinal and Optic Conditions
- Neonatal Respiratory Health Research
- Neonatal and fetal brain pathology
- Retinal Development and Disorders
- Healthcare professionals’ stress and burnout
- Cerebral Venous Sinus Thrombosis
- Workplace Health and Well-being
- Educational Technology and Pedagogy
- Cancer Treatment and Pharmacology
- Virus-based gene therapy research
- Ophthalmology and Eye Disorders
- Chemotherapy-induced cardiotoxicity and mitigation
- Traumatic Brain Injury and Neurovascular Disturbances
- Corneal Surgery and Treatments
- Higher Education and Teaching Methods
- Employment and Welfare Studies
- Education and Work Dynamics
- Colorectal Cancer Treatments and Studies
- Angiogenesis and VEGF in Cancer
Central South University
2024-2025
Sichuan University
2020-2025
West China Second University Hospital of Sichuan University
2020-2025
He Eye Hospital
2022-2024
Guangdong Academy of Medical Sciences
2024
Southern Medical University
2024
Guangdong Provincial People's Hospital
2024
Hunan Provincial Science and Technology Department
2024
Naval University of Engineering
2024
Peking University
2024
Detecting elevated intracranial pressure in children with subacute conditions, such as craniosynostosis or tumor, may enable timely intervention and prevent neurocognitive impairment, but conventional techniques are invasive often equivocal. Elevated leads to structural changes the peripapillary retina. Spectral-domain (SD) optical coherence tomography (OCT) can noninvasively quantify retinal layers a micron-level resolution.To evaluate whether measurements from OCT serve an effective...
Over the last two decades, prevalence of myopia has gradually increased in China. Numerous epidemiological studies suggest that education and inadequate time spent outdoors are major causes current epidemic. China is one few countries begun to address epidemic with a national-level strategy, implementing nationwide reform, cost-reduction measurements, dissemination information on prevention control. These "natural experiments" will provide insights into areas may face similar or potential problems.
Abstract Purpose The purpose of this study was to determine the relationship between macular sensitivity (MS) and posterior staphyloma (PS) in highly myopic eyes. Methods This cross‐sectional, observational included 646 eyes (spherical equivalent (SE) ≤−5.00D international meta‐analysis for pathologic myopia classification grade <2) from 362 participants. MS measured using microperimetry evaluated with without PS. Correlations PS were determined multivariate regression models. Results...
Abstract Reduced time outdoors is an important factor promoting the development of myopia. The spatial frequency spectra man-made indoor and outdoor environments, which are impoverished in high frequencies (HSF), may be a contributor to human myopia development. This randomized clinical trial aimed investigate whether HSF enhancing classroom-- scene classroom (OSC) can arrest children. Here we showed OSC was protective slowing down myopic shift among children who were not at baseline....
To determine recent trends in and sociodemographic/comorbid conditions associated with penetrating keratoplasty (PK) lamellar (LK) for keratoconus (KCN).Patients KCN subsequent PK LK procedures were identified using International Classification of Diseases, 9th revision (ICD-9) Current Procedural Terminology (CPT) billing codes. The change surgical rates was calculated over a decade, multivariate analysis demonstrated factors undergoing surgery.A total 21,588 patients underwent 1306 109...
Abstract Background This study aimed to improve and implement the central sterile supply department (CSSD) training program through action research evaluate its effect. Materials methods The project was underpinned by research. problems that occurred in were identified following scenario analysis, interviews, group discussions, expert consultation develop improvement measures. characterized CSSD developed spiral circular process of “Plan-Act-Observe-Reflect”. Results After two rounds...
Central sterile supply department (CSSD) is an important in the hospital. It can ensure successful sterilization and nosocomial infection control. CSSD staff are often interrupted during cleaning, disinfection, packaging, distribution. This study investigated nursing interruptions CSSDs China, aiming to understand current situations demands of training on interruptions. also examined whether there were differences among nurses with different characteristics, so as provide a reference for...
Purpose To assess the prevalence and risk factors of myopic macular degeneration (MMD) in young middle-aged individuals with high myopia Changsha, central China. Methods A total 445 adults (worse than or equal to −5.0 D) were examined between 2021 2023. Autorefraction biometry using IOLMaster conducted, fundus photos graded for MMD Meta-PM criteria. was diagnosed if category 2, 3, 4 any plus lesion present. Risk such as age, gender, spherical equivalent (SE)/axial length (AL), body mass...
Whereas Alzheimer disease (AD) is associated with inner retina thinning visualized by spectral-domain optical coherence tomography (SD-OCT), we sought to determine if the has a distinguishing biomarker for frontotemporal degeneration (FTD).Using cross-sectional design, examined retinal structure in 38 consecutively enrolled patients FTD and 44 controls using standard SD-OCT protocol. Retinal layers were segmented Iowa Reference Algorithm. Subgroups of highly predictive molecular pathology...
In this article, we propose a regression method for simultaneous supervised clustering and feature selection over given undirected graph, where homogeneous groups or clusters are estimated as well informative predictors, with each predictor corresponding to one node in the graph connecting path indicating priori possible grouping among predictors. The seeks parsimonious model high predictive power through identifying collapsing of coefficients. To address computational challenges, present an...
Applied Genetic Technologies Corporation (AGTC) is developing a recombinant adeno-associated virus (rAAV) vector AGTC-501, also designated rAAV2tYF-GRK1-hRPGRco, to treat X-linked retinitis pigmentosa (XLRP) in patients with mutations the GTPase regulator (RPGR) gene. The contains codon-optimized human RPGR cDNA (hRPGRco) driven by photoreceptor-specific promoter (G protein-coupled receptor kinase 1 [GRK1]), and packaged an AAV2 capsid variant three surface tyrosine residues changed...
Understanding the role of vitamin D-which regulates inflammatory responses-in noninfectious uveitis (an disease) may provide insight into treatment and prevention this disease.To investigate whether there is an association between hypovitaminosis D incident uveitis.In a retrospective case-control study, data from health care claims database containing deidentified medical large private insurer were used to identify 558 adults enrolled January 1, 2000, December 31, 2016, who received...
Objective: While Alzheimer’s disease is associated with inner retina thinning measured by spectral-domain optical coherence tomography (SD-OCT), our previous cross-sectional study suggested outer in frontotemporal degeneration (FTD) patients compared to controls without neurodegenerative disease; we sought evaluate longitudinal changes of this potential biomarker. Methods: SD-OCT retinal layer thicknesses were at baseline and after 1-2 years. Clinical criteria, genetic analysis, a...
SIGNIFICANCE The spatial frequency spectrum of the environment has been proposed as a risk factor for myopia development. However, this hypothesis not yet directly tested in humans. PURPOSE This study aimed to investigate impact on childhood classrooms with properties resembling those outdoor environments. article describes design, baseline characteristics, and acceptability strategy. METHODS Classrooms had custom-made wallpaper installed forest sky scenes that spectra comparable...