A5038263287- Computational Drug Discovery Methods
- Synthesis and biological activity
- Multicomponent Synthesis of Heterocycles
- Synthesis of heterocyclic compounds
- Quinazolinone synthesis and applications
- Synthesis and Characterization of Heterocyclic Compounds
- Click Chemistry and Applications
- Chemistry and Chemical Engineering
Sidi Mohamed Ben Abdellah University
2022-2025
The synthesis of 5,6,7,8-tetrahydro-[1,2,4]triazolo[5,1-b]quinazolin-9(4H)-one (THTQ), a potentially biologically active compound, was pursued, and its structure determined through sequence spectral analysis, including 1H-NMR, 13C-NMR, IR, HRMS. Four bacterial four fungal strains were evaluated for their susceptibility to the antibacterial antifungal properties THTQ compound using well diffusion method. impact on corrosion mild steel in 1 M HCl solution various methods such as weight loss,...
Background/Objectives: Antimicrobial resistance and oxidative stress are major global health challenges, necessitating the development of novel therapeutic agents. Pyrazole derivatives, known for their diverse pharmacological properties, hold promise in addressing these issues. This study aimed to synthesize new mono- bis-pyrazole derivatives using an eco-friendly, catalyst-free approach evaluate antioxidant, antibacterial, antifungal activities, supported by silico ADMET profiling,...