A5081285529- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Gastrointestinal Bleeding Diagnosis and Treatment
- Diverticular Disease and Complications
- Congenital gastrointestinal and neural anomalies
- Pelvic floor disorders treatments
- Anorectal Disease Treatments and Outcomes
- Appendicitis Diagnosis and Management
- Gastrointestinal disorders and treatments
- Helicobacter pylori-related gastroenterology studies
- Abdominal Surgery and Complications
- Colorectal Cancer Surgical Treatments
- Intraperitoneal and Appendiceal Malignancies
- Mycobacterium research and diagnosis
- Esophageal Cancer Research and Treatment
- AI in cancer detection
- Surgical Simulation and Training
- Intestinal and Peritoneal Adhesions
- Microscopic Colitis
- Traumatic Brain Injury and Neurovascular Disturbances
- Abdominal Trauma and Injuries
- Colorectal and Anal Carcinomas
- Gynecological conditions and treatments
- Spinal Fractures and Fixation Techniques
- Neurosurgical Procedures and Complications
University of Southern Denmark
2020-2025
Odense University Hospital
2016-2025
Svendborg Sygehus
2020-2024
Slagelse Hospital
2013
Holbæk Sygehus
2012-2013
To investigate whether the prokinetic prucalopride increases completion rate of colon capsule endoscopy (CCE). Secondary outcomes included demographic distribution, polyp detection (PDR), distribution Leighton-Rex grade, and adverse events.In a nested cohort within CareForColon2015 trial, subgroup 406 individuals underwent CCE in 2021. The first half (control) received standard bowel preparation second (prucalopride) was supplemented with 2 mg prucalopride. Transit times preparations were...
Background Colonoscopy is among the standard tests for colorectal cancer (CRC) screening. However, uptake varies, and alternatives such as colon capsule endoscopy (CCE) are available. The detection rate of clinically significant neoplasia with CCE, compared colonoscopy, remain unclear in this setting. Objective primary objective study was to compare rates advanced between CCE using a pathway which group could choose two procedures, while control offered only colonoscopy. Design A randomised,...
Background and study aims The Danish CareForColon2015 trial, launched in 2020 as part of the Colorectal Cancer Screening program, is largest randomized controlled trial to date on colon capsule endoscopy (CCE). This paper presents interim analysis with objective ensuring safety patients intervention group evaluating clinical performance trial's predefined parameters. Patients methods We evaluated initial 234 CCEs according quality, safety, completion. participation rates preference...
Introduction The use of capsule endoscopy has become an approved method in small bowel diagnostics, but the same level integration is not seen large diagnostics. We will colon (CCE) as a filter test colorectal cancer (CRC) screening between faecal immunochemical (FIT) and colonoscopy. aim to investigate clinical performance, population acceptability, economic implications procedure large-scale trial. Methods analysis randomly allocate 124 214 Danish citizens eligible for participation...
BackgroundPopulation-based screening for colorectal cancer by a faecal immunochemical test (FIT) is recommended the European Union. Detectable haemoglobin can indicate neoplasia as well other conditions. A positive FIT predicts an increased risk of death from but might also predict all-cause mortality.MethodsA cohort participants was followed using Danish National Register Causes Death. Data were retrieved Colorectal Cancer Screening Database supplemented with concentrations. specific and...
Abstract Purpose When an optical colonoscopy is carried out, Scope Guide can assist the endoscopist in determining localization. In colon capsule endoscopy (CCE), this support not available. To our knowledge, interobserver agreement on landmark identification has never been studied. This study aims to investigate CCE. Methods An was out comparing (the ileocecal valve, hepatic flexure, splenic and anus) CCE investigations between external private contractor three in-house readers with...
Abstract Anorectal malformations (ARM) are a spectrum of anomalies the rectum and anal canal affecting 1 in 2500 to 5000 live births. Functional problems common related type ARM associated malformations. We aimed evaluate results Three-dimensional High Resolution Manometry (3D-HRAM) long-term follow-up after surgical correction with special reference fecal incontinence. Twenty-one patients anorectal primary repair at our center consented participate study. Pressures sphincter muscles defects...
Abstract We aimed to evaluate the etiologies of constipation in patients with anorectal malformations having a good prognosis for bowel control but high risk constipation. included twenty-five from Odense university hospital Denmark. Patients were subjected colon transit time examination and resolution manometry (HRAM). The median age was 18 (14–24) 48% (12/25) females. Fifty-two % (13/25) diagnosed Types malformation perineal fistula (9/25), rectovestibular (8/25), rectourethral bulbar...
Abstract Background Colorectal cancer (CRC) screening reduces all-cause and CRC-related mortality. New research demonstrates that the faecal haemoglobin concentration (f-Hb) may indicate presence of other serious diseases not related to CRC. We investigated association between f-Hb, measured by a immunochemical test (FIT), both mortality cause death in population-wide cohort participants. Methods Between 2014 2018, 1,262,165 participants submitted FIT for Danish CRC programme. followed these...
Abstract Aim In the Danish Colorectal Cancer Screening Program (DCCSP), 37% of participants undergoing colonoscopy have a negative result with no obvious findings that can be attributed to positive faecal immunochemical test (FIT). The aim this work was identify predictors for in DCCSP FIT. Method We included 73 655 FIT‐positive using Database and linked their screening results data from several other national health registers. stratified by all predictors, compared them multivariate...
Colon capsule endoscopy (CCE) was introduced nearly two decades ago. Initially, it limited by poor image quality and short battery time, but due to technical improvements, has become an equal diagnostic alternative optical colonoscopy (OC). Hastened the coronavirus disease 2019 pandemic, CCE been in clinical practice relieve overburdened units move investigations out-patient clinics. A wider adoption of would be bolstered positive patient experience, as offers a investigation that is not...
Prompted by the core idea of wireless capsule endoscopy as a painless gastrointestinal examination, and easy adoption small bowel endoscopy, armamentarium capsule-based imaging platforms has grown to include colon devices well [...]
Background and AimsColon capsule endoscopy (CCE) faces substantial challenges, one of which is achieving adequate colon cleansing. Furthermore, the interobserver agreement on bowel-cleansing quality varies. To address this issue, we developed an artificial intelligence algorithm (AIA) to evaluate quality. The aim study was estimate bowel cleansing between a group experienced CCE readers AIA examine whether percentiles overall are suitable way reporting results generated by...
Follow-up after an episode of colonic diverticulitis is a common indication for colonoscopy, even though studies have shown low risk positive findings in this population. Our objective to investigate colon capsule endoscopy (CCE) as follow-up examination patients with compared particularly regarding patient satisfaction and clinical performance.We will conduct single-centre prospective randomised controlled trial. Patients seen at Odense University Hospital acute confirmed by CT be included...