A5087018239- Global Maternal and Child Health
- Healthcare Systems and Reforms
- COVID-19 epidemiological studies
- Food Security and Health in Diverse Populations
- Emergency and Acute Care Studies
- Pneumonia and Respiratory Infections
- COVID-19 Impact on Reproduction
- Global Public Health Policies and Epidemiology
- Immune responses and vaccinations
- Global Health Workforce Issues
- Maternal and Perinatal Health Interventions
- Vaccine Coverage and Hesitancy
- COVID-19 and Mental Health
- Mental Health Treatment and Access
- Chronic Disease Management Strategies
- Primary Care and Health Outcomes
- Health, psychology, and well-being
- COVID-19 Digital Contact Tracing
- Diabetes Management and Education
- Maternal and Neonatal Healthcare
- Family and Patient Care in Intensive Care Units
- Community Health and Development
- Public Health Policies and Education
- Mental Health and Patient Involvement
- Social Issues and Sustainability
Partners In Health
2022-2024
El Colegio de la Frontera Sur
2022-2023
Brown University
2022
Duke Institute for Health Innovation
2022
Hofstra University
2022
Impact
2022
Departamento de Salud
2022
University College London
2020
Centre for Genomic Regulation
2016
Barcelona Institute for Science and Technology
2016
Huntington's disease (HD) is a polyglutamine disorder caused by CAG expansion in the Huntingtin (HTT) gene exon 1. This encodes mutant protein whose abnormal function traditionally associated with HD pathogenesis; however, recent evidence has also linked pathogenesis to RNA stable hairpins formed HTT expansion. Here, we have shown that locked nucleic acid-modified antisense oligonucleotide complementary repeat (LNA-CTG) preferentially binds without affecting mRNA or levels. LNA-CTGs produced...
The COVID-19 pandemic has disrupted health services worldwide, which may have led to increased mortality and secondary disease outbreaks. Disruptions vary by patient population, geographic area, service. While many reasons been put forward explain disruptions, few studies empirically investigated their causes. We quantify disruptions outpatient services, facility-based deliveries, family planning in seven low- middle-income countries during the relationships between intensity of national...
Appropriate and timely care seeking can reduce pneumonia deaths, but are influenced by caregivers community norms of health illness. We explore caregiver perceptions, care-seeking experience, childhood pneumonia, to understand contexts that drive pediatric service uptake in Nigeria.Community group discussions qualitative interviews with Lagos Jigawa states were completed between 1 November 2018 31 May 2019. Participants recruited from purposively sampled facility catchment areas assistance...
Abstract Background Case fatality rates for childhood pneumonia in Nigeria remain high. There is a clear need improved case management of pneumonia, through the sustainable implementation Integrated Management Childhood Illnesses (IMCI) diagnostic and treatment algorithms. We explored barriers opportunities Lagos Jigawa states, Nigeria. Methods A mixed‐method analysis was conducted to assess current health system capacity deliver quality care. This done audits 16 facilities 14 Lagos,...
Mexico is one of the countries with greatest excess death due to COVID-19. Chiapas, poorest state in country, has been particularly affected. Faced an exacerbated shortage health professionals, medical supplies, and infrastructure respond pandemic, non-governmental organization Compañeros En Salud (CES) implemented a COVID-19 infection prevention control program limit impact pandemic region. We evaluated CES's implementation community worker (CHW)-led contact tracing intervention eight rural...
Interventions to reduce pneumonia mortality exist; however, stakeholder engagement is needed prioritize these. We explored diverse opinions on current policy challenges and priorities for pediatric in Nigeria.We conducted a mixed-methods study, with web-survey semi-structured interviews, explore roles, barriers, opportunities, priorities. Web-survey participants were identified through mapping, including researchers' networks, academic grey literature, "Every Breath Counts" coalition...
Following the first COVID-19 case in Chiapas, Mexico March 2020, non-governmental organisation Compañeros En Salud (CES) and state's Ministry of Health (MOH) decided to join forces respond global pandemic. The collaboration was built over 8 years partnership bring healthcare underserved populations Sierra Madre region. response consisted a comprehensive SARS-CoV-2 infection prevention control programme, which included through communication campaigns combat misinformation stigma related...
Background The COVID-19 pandemic has stricken mental health worldwide. Marginalized populations in low- and middle-income countries have been the most affected, as they were already experiencing barriers to accessing care prior are unequally exposed stressors associated with emergency, such economic ravages or increased risk of complicated disease outcomes.Objective aim this paper is describe a comprehensive initiative resulting from public-civil partnership address burden illness rural...
Background Global prevalence of diabetes is increasing, causing widespread morbidity, mortality and increased healthcare costs. Providing quality care in a timely fashion to people with low-resource settings can be challenging. In the underserved state Chiapas, Mexico, which has some lowest detection control rates country, there need implement strategies that improve for patients diabetes. One such strategy shared medical appointments (SMAs), patient-centred approach proven effective...
Many Mexicans face barriers to receive delivery care from qualified professionals, especially indigenous and poor sectors of the population, which represent most population in state Chiapas. When access institutional is an option, experiences with childbirth are often poor. This underscores need for evidence improve quality services user's perspective. The present study was conceived objective understanding how non-clinical aspects shape women's birthing public health institutions
The model of obstetric care predominant in Mexico most public and private healthcare institutions is particularly focused on a physiological perspective the female body that does not respond to women's need for emotional comfort satisfaction. In last decade, however, various initiatives provide centered rights have emerged.
Globally, obstetric emergencies majorly account for maternal morbidity and mortality. Guerrero, Oaxaca Chiapas accounted more than 13% of deaths in the country 2021. Obstetric haemorrhage was leading cause death after COVID-19 infection hypertensive disorders. This case highlights clinical course social determinants health that limited access to services a young woman with an emergency rural southern Mexico. The describes common challenges during resource-poor settings, such as timely...