A5049415543- Global Maternal and Child Health
- Advanced Causal Inference Techniques
- Reproductive Health and Contraception
- COVID-19 epidemiological studies
- Statistical Methods and Bayesian Inference
- Reproductive Health and Technologies
- SARS-CoV-2 detection and testing
- Gestational Diabetes Research and Management
- Healthcare Systems and Reforms
- Child Nutrition and Water Access
- SARS-CoV-2 and COVID-19 Research
- Poverty, Education, and Child Welfare
- Pregnancy and preeclampsia studies
- COVID-19 Impact on Reproduction
- Vaccine Coverage and Hesitancy
- Statistical Methods and Inference
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 and healthcare impacts
- Ectopic Pregnancy Diagnosis and Management
- Birth, Development, and Health
- Maternal and Perinatal Health Interventions
- Statistical Methods in Clinical Trials
- Endometriosis Research and Treatment
- Ethics and Legal Issues in Pediatric Healthcare
- Biosensors and Analytical Detection
Planned Parenthood
2019-2025
Harvard University
2016-2024
Harvard University Press
2021-2024
Right to Care
2024
Harvard Global Health Institute
2017-2024
D-Tree International
2023
University of Hawaiʻi at Mānoa
2022
University of Hawaii System
2022
The University of Texas Southwestern Medical Center
2022
Brigham and Women's Hospital
2019-2022
Objective To examine changes in vaccination of children younger than 1 year during the coronavirus disease 2019 (COVID-19) pandemic (March 2020-August 2021) Haiti, Lesotho, Liberia and Malawi.Methods We used data from health management information systems on aged 12 months or districts supported by Partners In Health.We January 2016 to February 2020 a linear model with negative binomial distribution estimate expected immunization counts for March 2021 95% prediction intervals, assuming no...
OBJECTIVE: To compare immediate initiation with delayed of medication abortion among patients an undesired pregnancy unknown location. METHODS: This retrospective cohort study used electronic medical record data from the Planned Parenthood League Massachusetts (2014–2019) for who requested a last menstrual period (LMP) 42 days or less and location (no gestational sac) on initial ultrasonogram. Clinicians could initiate mifepristone followed by misoprostol while simultaneously excluding...
Methods for inferring average causal effects have traditionally relied on two key assumptions: (i) the intervention received by one unit cannot causally influence outcome of another; and (ii) units can be organized into nonoverlapping groups such that outcomes in separate are independent. In this article, we develop new statistical methods inference based a single realization network connected which neither assumption nor holds. The proposed approach allows both arbitrary forms interference,...
Objectives. To measure the effect of ROE Act on abortion timing for adolescents aged 16 to 17 years in Massachusetts. Methods. The primary outcome was gestational duration at individuals 19 Planned Parenthood League Massachusetts from 2017 2022. Our control group included 18 undergoing abortions. In our analysis, we used a comparative interrupted time series with linear model capture temporal trends, seasonality, whether an undergone during acute phase COVID-19 pandemic, previous abortion,...
The COVID-19 pandemic has disrupted health services worldwide, which may have led to increased mortality and secondary disease outbreaks. Disruptions vary by patient population, geographic area, service. While many reasons been put forward explain disruptions, few studies empirically investigated their causes. We quantify disruptions outpatient services, facility-based deliveries, family planning in seven low- middle-income countries during the relationships between intensity of national...
Abstract Background Many children in low- and middle-income countries fail to reach their cognitive potential, with experiences before age 3 critical shaping long-term development. Zanzibar’s Jamii ni Afya program is the first national, digitally enabled community health volunteer (CHV) promoting early childhood development (ECD) following Nurturing Care Framework within an integrated maternal child healthcare package. Using baseline data, we explored home environment, caregivers’ parenting,...
Recent advances in causal mediation analysis have formalized conditions for estimating direct and indirect effects various contexts. These approaches been extended to a number of models survival outcomes including accelerated failure time models, which are widely used broad range health applications given their intuitive interpretation. In this setting, it has suggested that under standard assumptions, the "difference" "product" methods produce equivalent estimates effect exposure on...
To describe individual-level delay in obtaining abortion associated with use of the Massachusetts judicial bypass system, which legal minors (aged 17 years or younger) to obtain without consent a parent guardian setting Massachusetts' parental law for abortion.We conducted retrospective cohort study 2,026 abortions among at large, statewide network clinics between 2010 and 2016. Delay was defined as number calendar days minor's first call clinic schedule an abortion, day received.In...
Uncovering and addressing disparities in infectious disease outbreaks require a rapid, methodical understanding of local epidemiology. We conducted seroprevalence study SARS-CoV-2 infection Holyoke, Massachusetts, majority Hispanic city with high levels socio-economic disadvantage to estimate identify infection. invited 2000 randomly sampled households between 11/5/2020 12/31/2020 complete questionnaires provide dried blood spots for antibody testing. calculated based on the presence IgG...
Summary Standard methods for inference about direct and indirect effects require stringent no-unmeasured-confounding assumptions which often fail to hold in practice, particularly observational studies. The goal of the paper is introduce a new form effect, population intervention that can be non-parametrically identified presence an unmeasured common cause exposure outcome. This type effect captures extent mediated by intermediate variable under holds component directly influencing outcome...
Early detection of SARS-CoV-2 circulation is imperative to inform local public health response. However, it has been hindered by limited access diagnostic tests and testing infrastructure. In regions with capacity, routinely collected data might be leveraged identify geographical locales experiencing higher than expected rates COVID-19-associated symptoms for more specific activities.We developed syndromic surveillance tools analyse aggregated facility on COVID-19-related indicators in seven...
The use of causal mediation analysis to evaluate the pathways by which an exposure affects outcome is widespread in social and biomedical sciences. Recent advances this area have established formal conditions for identification estimation natural direct indirect effects. However, these typically involve stringent assumptions no unmeasured confounding that mediator has been measured without error. These may fail hold many practical settings where methods are applied. goal article two-fold....
Background Our objective was to assess differences in TB treatment outcomes between individuals who were HIV negative, positive on anti-retroviral (ART) and not ART, at initiation a rural district hospital Eastern Cape, South Africa. Methods This retrospective cohort study of diagnosed with January 2017 April 2020 hospital. Adults 15 years over reported status outcome included (N = 711). A categorical three levels considered: unfavorable, down referral, success. We report descriptive...
Background Maternal and neonatal health outcomes in low- middle-income countries (LMICs) have improved over the last two decades. However, many pregnant women still deliver at home, which increases risks for both mother child. Community worker programs been broadly employed LMICs to connect antenatal care delivery locations. More recently, employment of digital tools maternal resulted better served as a routine mode data collection. Despite availability rich, patient-level within these...
Mexico is one of the countries with greatest excess death due to COVID-19. Chiapas, poorest state in country, has been particularly affected. Faced an exacerbated shortage health professionals, medical supplies, and infrastructure respond pandemic, non-governmental organization Compañeros En Salud (CES) implemented a COVID-19 infection prevention control program limit impact pandemic region. We evaluated CES's implementation community worker (CHW)-led contact tracing intervention eight rural...
Abstract User engagement with remote blood pressure monitoring during pregnancy is critical to optimize the associated benefits of control and early detection hypertensive disorders pregnancy. In our study population pregnant individuals, we found that connected cuffs, which automatically sync measures a platform or health record, increase (2.13 [95% CI 1.36‐3.35] times more per day) compared unconnected cuffs require manual entry measures.
Abstract Background Most maternal health programs in low- and middle- income countries estimate gestational age to provide appropriate antenatal care at the correct times throughout pregnancy. Although various dating methods have been validated research studies, performance of these has not evaluated on a larger scale, such as within systems. The objective this was investigate magnitude impact errors estimated delivery dates facility among women enrolled program Zanzibar. Methods This study...
Abstract The utilization of community health worker (CHW) programmes to improve maternal and neonatal outcomes has become widely applied in low- middle-income countries. While current research focused on discerning the effect these interventions, documenting process implementing, scaling sustaining been largely ignored. Here, we implementation Safer Deliveries CHW programme Zanzibar, a designed address high rates mortality by increasing facility delivery postnatal care visits. was...