A5015000084- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Biology and Fertility
- Ovarian function and disorders
- Reproductive Health and Technologies
- Reproductive System and Pregnancy
- Ectopic Pregnancy Diagnosis and Management
- Genetic Syndromes and Imprinting
- Sperm and Testicular Function
- Parvovirus B19 Infection Studies
- Genomic variations and chromosomal abnormalities
- Endometriosis Research and Treatment
- Celiac Disease Research and Management
- Gynecological conditions and treatments
- Endometrial and Cervical Cancer Treatments
- Pregnancy and preeclampsia studies
- Family Dynamics and Relationships
- Epigenetics and DNA Methylation
- Diversity and Career in Medicine
- Birth, Development, and Health
- Reproductive Health and Contraception
- Ovarian cancer diagnosis and treatment
- Uterine Myomas and Treatments
- Fetal and Pediatric Neurological Disorders
- Cystic Fibrosis Research Advances
Duke University Health System
2024
Children's Mercy Hospital
2023
SUNY Morrisville
2023
Duke University
2023
Duke University Hospital
2023
Duke Medical Center
2023
Thomas Jefferson University
2016-2021
Reproductive Medicine Associates of New Jersey
2014-2020
Medical University of South Carolina
2014-2018
MUSC Hollings Cancer Center
2017
Do infertile women aged <38 years with quantitative evidence of diminished ovarian reserve and/or poor response to stimulation also exhibit oocyte quality as measured by blastulation rates, aneuploidy and live birth rates?Young accelerated follicular depletion, either precycle testing or postcycle low yield, equivalent rates per euploid embryo transfer age-matched controls normal parameters.Previous studies are conflicted whether at increased risk exhibiting quality. Most prior have failed...
The purpose of the study is to validate a method that provides opportunity distinguish balanced translocation carrier embryo from truly normal in parallel with comprehensive chromosome screening (CCS). A series couples underwent IVF single nucleotide polymorphism (SNP) array-based CCS on 148 embryos were included. Predictions or status each made based upon embryonic SNP genotypes. In one case, microdeletion was used designate whether normal. 10 additional cases, conventional karyotyping...
The objectives of this study were (1) to assess the prevalence ultrasound (US) features adenomyosis in an infertile population undergoing in-vitro fertilization (IVF), (2) define inter- and intrarater agreement three-dimensional (3D) US assessment adenomyosis, (3) evaluate sonographic with respect pregnancy outcome following transfer a single thawed euploid blastocyst.This was prospective cohort study. Subjects scheduled undergo blastocyst between April December 2017 at large IVF center...
To determine whether differences exist in rates of subchromosomal abnormalities, mosaicism, and "no call" results among embryologists performing loading trophectoderm biopsies for preimplantation genetic testing aneuploidy (PGT-A).Retrospective cohort.Large infertility center.All patients undergoing vitro fertilization with PGT-A.The NexCCS next generation sequencing platform was used PGT-A. The χ2 assessed primary outcomes between embryologists. Intraclass correlation coefficients evaluated...
African American (AA) females with endometrial carcinoma have a significantly worse prognosis regard to disease-free survival and overall than their European (EA) counterparts this finding is true across all stages grades. The presence of tumor-infiltrating lymphocytes (TILs) has been demonstrated be prognostic significance in variety malignancies, including cancers. This study aims determine whether clinically significant differences levels CD8+ cytotoxic T lymphocytes, FoxP3+ regulatory...
Advanced subspecialty training in reproductive endocrinology and infertility (REI) entails a competitive application process with many data points considered. It is not known what components weigh more heavily for applicants. Thus, we sought to study the REI fellow applicant compare 1) those who apply but do receive an interview, 2) interview match, 3) successfully match. This retrospective cohort was conducted at single fellowship program from 2013 2017. Academic variables assessed included...
In mammals, the oxygen (O2) tension in uterus is lower (2%) than oviduct (5-7%). This fits with a shift metabolic strategy of embryo after compaction and may have implications for EC clinical IVF. Indeed, recent study utilizing discarded human embryos, blastulation rates were superior when cultured 2% compared to 5% day (d) 3. However, it exceedingly difficult control myriad factors impacting employing material. Thus, this sought gain further insight into impact ultra-low O2 using...
To determine if trophectoderm (TE) grade or inner cell mass (ICM) have predictive value after euploid frozen embryo transfer (euFET) among RPL patients.Retrospective cohort study.Single fertility center, 2012-2018.Patients with ≥ 2 prior pregnancy losses performing PGT-A ≥1 for transfer.All patients underwent ICSI, biopsy, blastocyst grading and vitrification, single euFET. Outcome of the first was recorded.Live birth (LB) clinical miscarriage (CM) rates.660 euFET were included. In a...