A5010600416- Assisted Reproductive Technology and Twin Pregnancy
- Prenatal Screening and Diagnostics
- Reproductive Biology and Fertility
- Ovarian function and disorders
- Reproductive Health and Technologies
- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Ectopic Pregnancy Diagnosis and Management
- Gynecological conditions and treatments
- Uterine Myomas and Treatments
- Pregnancy and preeclampsia studies
- Genetic Syndromes and Imprinting
- Gestational Trophoblastic Disease Studies
- Genomic variations and chromosomal abnormalities
- Reproductive Health and Contraception
- Maternal and fetal healthcare
- Sexual Differentiation and Disorders
- Preterm Birth and Chorioamnionitis
- Sperm and Testicular Function
- Grief, Bereavement, and Mental Health
- Sexual function and dysfunction studies
- Pregnancy and Medication Impact
- Congenital Anomalies and Fetal Surgery
- Ovarian cancer diagnosis and treatment
- Renal and related cancers
Stanford University
2016-2025
Stanford Medicine
2015-2025
Stanford Health Care
2012-2024
Lucile Packard Children's Hospital
2024
Northwestern University
2018
Stanford Blood Center
2016
Palo Alto University
2007-2016
Natera (United States)
2014
Columbia University
2014
American Society of Human Genetics
2014
In Brief OBJECTIVE: To report the full cohort of identifiable anomalies, regardless known clinical significance, in a large-scale postmiscarriage products-of-conception samples analyzed using high-resolution single-nucleotide polymorphism (SNP)–based microarray platform. High-resolution chromosomal analysis allows for identification visible and submicroscopic cytogenomic imbalances; specific use SNPs permits detection maternal cell contamination, triploidy, uniparental disomy. METHODS:...
In an intent to treat analysis, are clinical outcomes improved in recurrent pregnancy loss (RPL) patients undergoing IVF and preimplantation genetic screening (PGS) compared with who expectantly managed (EM)?Among all attempts at PGS or EM among RPL patients, including rate, live birth (LB) rate miscarriage (CM) were similar.The standard of care for management is EM. Due the prevalence aneuploidy CM, has been proposed as alternate strategy reducing CM rates improving LB rates.Retrospective...
No AccessJournal of UrologyAdult Urology1 Mar 2013Frequency the Male Infertility Evaluation: Data from National Survey Family Growth Michael L. Eisenberg, Ruth B. Lathi, Valerie Baker, Lynn M. Westphal, Amin A. Milki, and Ajay K. Nangia EisenbergMichael Eisenberg Department Urology, Stanford, California Obstetrics Gynecology, , LathiRuth Lathi BakerValerie Baker WestphalLynn Westphal MilkiAmin Milki NangiaAjay Kansas University School Medicine, City, View All Author...
Recurrent pregnancy loss (RPL) occurs in ∼5% of women. However, the etiology is still poorly understood. Defects decidualization endometrium during early contribute to several complications, such as pre-eclampsia and intrauterine growth restriction (IUGR), are believed be important pathogenesis idiopathic RPL. We performed microarray analysis identify gene expression alterations deciduas RPL patients. Control patients had one antecedent term delivery, but were undergoing dilation curettage...
The field of reproductive endocrinology and infertility (REI) is at a crossroads; there mismatch between demand for endocrinology, assisted technology (ART) services, availability care. This document's focus to provide data justifying the critical need increased provision fertility services in United States now into future, offer approaches rectify developing physician shortage problem, suggest framework discussion on how meet that increase demand. Society REI recommend following: 1. Our...
Obesity has been identified as a risk factor for spontaneous miscarriage although the mechanism is unclear. The purpose of this study to better understand effect obesity on early pregnancy success by examining cytogenetic results miscarriages in women with normal and elevated body mass index (BMI).We conducted retrospective case-control an academic infertility practice. Medical records ages <40 years first trimester missed abortion (n = 204), who underwent dilatation curettage between 1999...
ObjectiveTo compare chromosome testing of miscarriage specimens between traditional cytogenetic analysis and molecular karyotyping using single nucleotide polymorphism microarrays (SNP) array comparative genomic hybridization (aCGH).DesignProspective blinded cohort study.SettingUniversity–based practice.Patient(s)Women undergoing dilation curettage for first-trimester March 2014 December 2015.Intervention(s)None.Main Outcome Measure(s)Chromosome from chorionic villi separated equally...
Abstract Purpose Miscarriage, often resulting from a variety of genetic factors, is common pregnancy outcome. Preconception carrier screening (PGCS) identifies at-risk partners for newborn disorders; however, PGCS panels currently lack miscarriage-related genes. In this study, we evaluated the potential impact both known and candidate genes on prenatal lethality effectiveness in diverse populations. Methods We analyzed 125,748 human exome sequences mouse gene function databases. Our goals...