- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Cardiac Imaging and Diagnostics
- Radiology practices and education
- Photoacoustic and Ultrasonic Imaging
- Venous Thromboembolism Diagnosis and Management
- Medical Imaging and Analysis
- Vascular Procedures and Complications
- Artificial Intelligence in Healthcare and Education
- Lipid Membrane Structure and Behavior
- Neuroscience and Neuropharmacology Research
- Hydrology and Sediment Transport Processes
- Aortic aneurysm repair treatments
- Cardiac Valve Diseases and Treatments
- Glycosylation and Glycoproteins Research
- Digital Transformation in Industry
- Dam Engineering and Safety
- MRI in cancer diagnosis
- Educational Robotics and Engineering
- Dental Radiography and Imaging
- Hydraulic flow and structures
- Radiomics and Machine Learning in Medical Imaging
- Central Venous Catheters and Hemodialysis
- Spine and Intervertebral Disc Pathology
Goethe University Frankfurt
2014-2020
University Hospital Frankfurt
2014-2018
Justus-Liebig-Universität Gießen
2010
Among the large set of cell surface glycan structures, carbohydrate polymer polysialic acid (polySia) plays an important role in vertebrate brain development and synaptic plasticity. The main carrier polySia nervous system is neural adhesion molecule NCAM. As with chain lengths more than 40 sialic residues was still observed newborn Ncam −/− mice, we performed a glycoproteomics approach to identify underlying protein scaffolds. Affinity purification polysialylated molecules from followed by...
Purpose To evaluate whether a dual-energy (DE) computed tomographic (CT) virtual noncalcium technique can improve the detection rate of acute thoracolumbar vertebral compression fractures in patients with osteoporosis compared that at magnetic resonance (MR) imaging depending on level experience reading radiologist. Materials and Methods This retrospective study was approved by institutional ethics committee. Informed consent obtained from all patients. Forty-nine who were suspected having...
Purpose The aim of this study was to evaluate the diagnostic performance virtual noncalcium (VNCa) dual-energy computed tomography (DECT) reconstructions enabling visualization bone marrow edema for characterization incidental thoracolumbar compression fractures in routine thoracoabdominal staging (CT). Materials and Methods We retrospectively analyzed 51 oncological patients without suspected fracture or indicative complaints presenting at least 1 on DECT who had been examined between...
The purpose of the study was to evaluate 70 kVp dual-source computed tomography pulmonary angiography (CTPA) with reduced iodine load in comparison single-source and 100 CTPA standard regarding image quality radiation dose.Three groups 40 consecutive patients each underwent either (120 mAs; group A), (208 B), or (416 C). A volume mL contrast material 400 mg I/mL (groups A, B) 300 (group C) administered. Chest diameter, dose-length product, intravascular signal attenuation, noise, noise ratio...
The aim of the study was to evaluate objective and subjective image qualities virtual monoenergetic imaging (VMI) in dual-source dual-energy computed tomography (DECT) optimal kiloelectron-volt (keV) levels for lung cancer.Fifty-nine cancer patients underwent chest DECT. Images were reconstructed as VMI series at energy 40, 60, 80, 100 keV standard linear blending (M_0.3) comparison. Objective assessed.Lesion contrast peaked 40-keV reconstructions (2.5 ± 2.9) 60 (1.9 3.0), which superior...
<h3>BACKGROUND AND PURPOSE:</h3> Dose-saving techniques in neck CT cause increased image noise that can be counteracted by iterative reconstruction. Our aim was to evaluate the quality of advanced modeled reconstruction (ADMIRE) contrast-enhanced low-tube-voltage CT. <h3>MATERIALS METHODS:</h3> Sixty-one patients underwent 90-kV(peak) using third-generation 192-section dual-source Image series were reconstructed with standard filtered back-projection and ADMIRE strength levels 1, 3, 5....
Evaluation of latest generation automated attenuation-based tube potential selection (ATPS) impact on image quality and radiation dose in contrast-enhanced chest-abdomen-pelvis computed tomography examinations for gynaecologic cancer staging. This IRB approved single-centre, observer-blinded retrospective study with a waiver informed consent included total 100 patients CT All were examined activated ATPS adaption voltage to body habitus. 50 scanned third-generation dual-source (DSCT),...
Objective To investigate and compare the use of automated tube potential selection (ATPS) with current modulation (ATCM) in high-pitch dual-source computed tomographic angiography (CTA) for imaging whole aorta without electrocardiogram synchronization. Methods Two groups 60 patients underwent CTA on a device mode: ATCM (with 100-kV fixed potential) was used group 1 ATPS same image quality options) 2. For evaluation radiation exposure, CT dose index dose-length product were analyzed. Contrast...
To investigate image quality, and radiation dose between ECG-gated singlesource dual-source CT Angiography (CTA) protocols for planning of Trans-catheter Aortic Valve Implantation (TAVI) with a reference non single-source protocol.A total 120 patients were included in four groups: Non (SS), (SSECG), high-pitch (DSECG), or non-ECG-gated mode (DS). Qualitative quality the aortic annulus, valve, coronary ostia as well presence motion stair-step artefacts thoracic aorta independently assessed by...
The aim of this study was to evaluate the impact automated attenuation-based tube potential selection (ATPS) on image quality and radiation dose exposure parameters at a computed tomography angiography (CTA) lower-extremity runoff.Two hundred forty patients (156 men, 84 women) underwent CTA examinations runoff second-generation dual-source system: 120 fixed kV current 180 reference mAs, another using ATPS. Volume index (CTDIvol), dose-length-product (DLP), body diameters, noise,...
In selected cases, cuffed tunneled catheters via the iliac vein are implanted as a last resort access for hemodialysis. To monitor correct position, sonography of inferior vena cava (IVC) is sufficient in most cases. Position control using an X-ray abdomen not routinely recommended when femoral implanted. this report, we describe case 59-year-old patient on chronic hemodialysis due to granulomatosis with polyangiitis and complex shunt history multiple occlusions revisions. The implantation...
Computed tomography (CT) low-dose (LD) imaging is used to lower radiation exposure, especially in vascular imaging; current literature, this mostly on latest generation high-end CT systems.To evaluate the effects of reduced tube objective and subjective image quality a 15-year-old 16-slice system for pulmonary angiography (CTPA).CTPA scans from 60 prospectively randomized patients (28 men, 32 women) were examined study scanner system. Standard (SD) settings 100 kV 150 mAs, LD 50 mAs....
Purpose: The aim of the present study was to evaluate patient population, different MRI examination protocols and patient's acceptance endorectal coil in diagnosis prostate cancer regarding current discussion PI-RADS v2.1. Material Methods: In our institute, 256 patients were examined with separated into six groups. value identified by analyzing sensitivity, specificity, negative predictive positive value. population tested for statistically significant differences their characteristics...
In dieser Studie sollten objektive Bildqualitätsparameter evaluiert werden hinsichtlich abdomineller Dual-Energy computertomografischer Angiografie (DE-CTA) mithilfe des Monoenergetic Plus (Mono+) Rekonstruktionsalgorithmus im Vergleich zu konventionellen linear blended Bildserien.