A5010239137- Advanced Proteomics Techniques and Applications
- Carcinogens and Genotoxicity Assessment
- Glycosylation and Glycoproteins Research
- Pharmacogenetics and Drug Metabolism
- Drug Transport and Resistance Mechanisms
- Liver physiology and pathology
- Molecular Biology Techniques and Applications
- Diversity and Career in Medicine
- Cancer-related Molecular Pathways
- Body Image and Dysmorphia Studies
- Genomics, phytochemicals, and oxidative stress
- Byzantine Studies and History
- Drug-Induced Hepatotoxicity and Protection
- Digital Imaging in Medicine
- Ubiquitin and proteasome pathways
- Breast Implant and Reconstruction
- Enzyme Structure and Function
- Glutathione Transferases and Polymorphisms
- Reconstructive Surgery and Microvascular Techniques
- Mass Spectrometry Techniques and Applications
- Breast Cancer Treatment Studies
- Liver Disease Diagnosis and Treatment
- Pesticide Exposure and Toxicity
- Monoclonal and Polyclonal Antibodies Research
- Anesthesia and Pain Management
University of Wisconsin–Madison
2021-2025
Energy Center of Wisconsin
2024
Highland Community College - Illinois
2024
Alice Springs Hospital
2024
UW Health University Hospital
2022-2024
Creative Commons
2019-2023
Madison Group (United States)
2023
Leibniz Institute of Ecological Urban and Regional Development
2021
Georgetown University
2019-2020
Washington Center
2020
An endothelial cell inhibitor was purified from supernatant of an Epstein-Barr virus–immortalized line and identified as fragments calreticulin. The recombinant NH2-terminal domain calreticulin (amino acids 1–180) inhibited the proliferation cells, but not cells other lineages, suppressed angiogenesis in vivo. We have named this vasostatin. When inoculated into athymic mice, vasostatin significantly reduced growth human Burkitt lymphoma colon carcinoma. Compared with inhibitors angiogenesis,...
The human laminin receptor was purified and molecularly cloned to investigate its biosynthetic regulation. Laminin from normal neoplastic tissue preparatively affinity homogeneity based on the high of for laminin. apparent molecular weight different carcinoma sources placental is in range 68-72 kDa. Isoelectric focusing two-dimensional gel electrophoresis indicated that protein consists one major polypeptide chain with a pI value 6.4 +/- 0.2. cDNA clones were isolated after screening...
Summary: Integration of artificial intelligence (AI), specifically with natural language processing and machine learning, holds tremendous potential to enhance both clinical practices administrative workflows within plastic surgery. AI has been applied various aspects patient care in surgery, including postoperative free flap monitoring, evaluating preoperative risk assessments, analyzing documentation. Previous studies have demonstrated the ability interpret current procedural terminology...
The Ames bacterial mutagenesis system was used to evaluate the role of deacetylase and sulfotransferase in mutagenic activation N-hydroxy-2-acetylaminofluorene. mutagenicity N-hydroxy-2-acetylaminofluorene mediated by liver or kidney microsomes independent treatment mice rats with microsomal enzyme inducers and, at equivalent protein concentrations, same whether mouse were used. N-Hydroxy-2-acetylaminofluorene rat completely inhibited 0.1 mM paraoxon partially addition 39-phosphoadenosine...
Background: Current recommendations suggest that patient education materials (PEMs) be written at or below the sixth-grade reading level. In a 2010 study, average readability of PEMs on American Society Plastic Surgeons (ASPS) and The Aesthetic (AS) websites was found to 11th-grade level higher. We sought assess progress made toward providing accessible PEMs. Methods: were obtained from ASPS AS websites. entered into an online scoring tool. scored 3 common indices: Flesch–Kincaid, Simple...
Summary: Understanding the anatomy of an employment contract in plastic surgery is essential for achieving financial stability and advancing career goals. The lack formal training residents on contracts can make it challenging to secure favorable terms postgraduation, potentially leading dissatisfaction increased risk burnout. This review aimed provide a comprehensive overview key elements empower surgeons effective negotiation. It covers critical components, including compensation models,...
Animal thioredoxin reductases (TRs) are selenocysteine-containing flavoenzymes that utilize NADPH for reduction of thioredoxins and other protein nonprotein substrates. Three types mammalian TRs known, with TR1 being a cytosolic enzyme, TR3, mitochondrial enzyme. Previously characterized TR3 occurred as homodimers 55–57-kDa subunits. We report here isolated from mouse liver, liver tumor, human T-cell line exhibited extensive heterogeneity detected by electrophoretic, immunoblot, mass...
Two-dimensional gel electrophoresis with subsequent analysis by mass spectrometry was applied to study differences in protein expression between benign and malignant solid tumors from human beast, lung ovary cells. Cells freshly resected clinical material were lysed the extracts subjected isoelectric focusing immobilized pH gradients followed second-dimensional separation on 10—13% sodium dodecyl sulfate (SDS)/polyacrylamide gels. Polypeptides identified using matrix-assisted laser...
The mutageicity of phenacetin and acetaminophen their respective N-hydroxylated metabolites was determined in Salmonella typhimurium tester strains TA 98 100 both the presence absence liver kidney metabolic activating systems from rat, mouse, hamster, man. In neither phenacetin, acetaminophen, nor N-hydroxyacetaminophen mutagenic either or S-9 fractions 3-methylcholanthrene (3-MC)-induced rat untreated hamster microsomes. inclusion NADPH with S9 microsomal had no effect on any these...
The 2-hydroxyamino-3-methylimidazolo[4,5- f ]quinoline ( N hydroxy-IQ), a metaholite of the food mutagen-carcinogen IQ, was mutagenic to Salmonella TA98 (nitroreductase deficient). When either rat hepatic cytosol, NADPH (1 mM) or ascorbate (0.5 wasadded mutagenicity assay, increased up 15-, 10- and 50-fold respectively. In light effects NADPH, it appears likely that cytosol may contain factors protect -hydroxy-IQ from oxidative decomposition. contrast, monooxygenase metabolism decreased...
Abstract Historically, demand for plastic surgery has been associated with the performance of US economy. This study evaluates relationship between economic indicators and popularity profitability aesthetic from 2006 to 2022, considering several recessions rise social media. The data were collected Aesthetic Society's (AS) Plastic Surgery National Databank American Society Surgeons’ (ASPS) Statistics Report 2022. Procedures analyzed included most performed cosmetic surgeries, as well...