- Advanced Cellulose Research Studies
- Lignin and Wood Chemistry
- biodegradable polymer synthesis and properties
- Polysaccharides Composition and Applications
- Nanocomposite Films for Food Packaging
- Phytochemicals and Antioxidant Activities
- Natural Fiber Reinforced Composites
- Adsorption and biosorption for pollutant removal
- Wound Healing and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Polymer composites and self-healing
- Fermentation and Sensory Analysis
- Microencapsulation and Drying Processes
- Biochemical and biochemical processes
- Polysaccharides and Plant Cell Walls
- Hydrogels: synthesis, properties, applications
- Pickering emulsions and particle stabilization
- Advancements in Transdermal Drug Delivery
- Medicinal plant effects and applications
- Pharmacological Effects of Natural Compounds
- Tendon Structure and Treatment
- Phytochemical and Pharmacological Studies
- Polymer-Based Agricultural Enhancements
- Light effects on plants
- Ginger and Zingiberaceae research
Grigore T. Popa University of Medicine and Pharmacy
2022-2023
Institute of Macromolecular Chemistry
2022
Spitalul Clinic Judeţean de Urgenţe "Sf. Spiridon" Iaşi
2022
Institutul de Chimie Macromoleculară Petru Poni
2011-2022
Gheorghe Asachi Technical University of Iași
2019
Romanian Academy
2019
The study reported here presents a comparative screening of three medicinal plants including oregano (Origanum vulgare L.), lavender (Lavandula angustifolia) and lemon balm (Melissa officinalis) having the same geographical origin, Southeast region Romania, growing in natural conditions. contents total phenolics flavonoids for extracts these were determined. Furthermore, antioxidant capacity was also evaluated. It found that Origanum Melissa officinalis present most effective scavenging DPPH...
Biopolymeric drug delivery systems enhance the bioavailability and therapeutic efficacy of poorly soluble bioactive compounds. In this study, chitosan (Chi), dextran (Dex), carboxymethyl (mDex), lignin (L), curcumin (Cu) were combined to develop materials with controlled release, antioxidant, anti-inflammatory properties. The mechanical evaluation showed that Chi-mDex-L-Cu exhibited highest diametral tensile strength (2.40 MPa), a 1233% increase compared Chi-mDex-L, due strong hydrogen...
Here we present a new biomaterial based on cellulose, collagen and polyurethane, obtained by dissolving in butyl imidazole chloride. This material served as matrix for the incorporation of tannin lipoic acid, well bioactive substances with antioxidant properties. The introduction these principles into base led to an increase compressive strength range 105-139 kPa. An 29.85% mucoadhesiveness film containing tannin, compared reference, prolongs bioavailability active substance; fact also...
This study presents the development of new formulations consisting dextran (Dex) and chitosan (Ch) matrices, with fillings such as stearate (MCh), citric acid, salicylic or ginger extract. These materials were characterized using Fourier-Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM), mechanical tests, evaluated for antioxidant properties, including scavenging activities, metal chelation, ferric ion reducing power, well anti-inflammatory measuring binding affinity...
β-Cyclodextrin was attached to lignin/lignin crosslinked by epichlorohydrin and served as a drug delivery matrix. Ketoconazole piroxicam were added into the polymeric matrix antifungal anti-inflammatory agents, respectively. The percentage of retained ranged from 48.4% 58.4% for ketoconazole piroxicam, It found that their tensile strengths increased with decreasing particle size, ranging between 59% 71% lignin β-cyclodextrin base (LCD). Depending on matrix, release kinetics fit well in...
Designing composites based on natural polymers has attracted attention for more than a decade due to the possibility manufacture medical devices which are biocompatible with human body. Herein, we present some biomaterials made up of collagen, polyurethane, and cellulose doped lignin lignin-metal complex, served as transcutaneous drug delivery systems. Compared base material, compressive strength elastic modulus biocomposites comprising or complex were significantly enhanced; thus, increased...
Polylactic acid (PLA) was used as partial replacement for conventional thermoplastic matrix, new composites comprising cellulose, polypropylene (PP), and PLA being realized. In order to obtain a compatible interface between cellulosic pulp polymeric two chemical modifications of cellulose with stearoyl chloride toluene di-isocyanate (TDI) were performed, structural changes evidenced by X-ray photoelectron spectroscopy Fourier transform infrared spectroscopy. The composite materials...
Two polysaccharides (cellulose and chitosan) polyurethane dissolved in 1-ethyl-3-methylimidazolium chloride represented the matrix for obtainment of new composite formulations comprised lignin, ferrite-lignin hybrid ketoconazole. The mechanical performances (Young's modulus compressive strength) increased with filler addition. nature used studied influenced both bioadhesion mucoadhesion parameters. It was found that incorporation lignin into has vitro rate ketoconazole release, which is...
The present work is focused on developing new eco‐friendly materials based xanthan gum (XG) and cobalt ferrite (CF) nanoparticles with adsorptive properties. CF powder was prepared by the co‐precipitation method. Esterification of XG performed in order to improve its hydrophobic character, resulting acrylate (XGAC). Thin films were characterized. influence pH materials' composition their water uptake capacity investigated. Batch adsorption experiments evaluate dye materials. Materials...
ABSTRACT The esterification of cellulose hydroxyl groups with natural carboxylic acids in mild conditions represents an adequate pathway obtaining derivatives different useful properties. In this article, authors report the synthesis new mixed ester and acetate nicotinate (CAN) , a homogenous medium using DMF as solvent, (CA) starting cellulosic material, nicotinic acid agent presence p‐toluenesulfonyl chloride pyridine. FTIR NMR techniques were used to prove binding nicotinoyl group at free...
Adsorption of heavy metals (Pb, Zn, and Cu) on a new bioadsorbent based starch reinforced with modified cellulose toluene‐diisocyanate has been studied using batch‐adsorption technology. The study was carried out in order to find if this bio material, designed for seedling pots manufacture, is able act like barrier between soil pollutants plants. influence contact time, pH, adsorbent dose, salt concentrations also evaluated. obtained data were examined the Langmuir Freundlich adsorption...
This study focuses on the development of adsorptive materials to retain degraded 5w40 motor oil. The were prepared using xanthan (XG) and XG esterified with acrylic acid (XGAC) as polymeric matrix. LignoBoost lignin (LB), LB oleic (LBOL), stearic (LBST) montmorillonite (CL) added into XGAC matrices obtain adsorbents. Adsorption experiments revealed that XG/CL/LBOL had highest adsorption capacity at 46.80 g/g, followed by XGAC/CL 45.73 XG/CL 37.58 g/g. kinetic studies, employing...
The aims of this study were to develop composite films based on potato starch and cellulose modified with toluenediisocyanate, investigate their morphology structure, evaluate behavior enzymatic hydrolysis potential use manufacture biodegradable seedling pots. effects cellulosic fibers upon mechanical properties biodegradability materials matrix investigated by tensile strength tests, Fourier infrared spectroscopy, X‐ray diffraction, dynamic vapor sorption. the amylase cellulase was studied;...
Herbs have been used as food and for medicinal purposes centuries.In recent years, natural compounds such phenolic acids, diterpenes triterpenes, present in various plants, the subject of intense research due to their potential benefits human health.It has demonstrated that antioxidant radical scavenge activities are main properties these compounds.The difficulties using products a source pharmaceutical lead involve separating from original extract, well cost time money invested an activity...
The purpose of this study was to obtain and characterize some cellulose/collagen biocomposites comprising different antioxidant anti-inflammatory substances.The structure the obtained materials investigated using scanning electron microscopy (SEM) attenuated total reflection infrared spectroscopy (FTIR).Additionally, mechanical biological characteristics were evaluated in order identify potential applications.The properties studied suggest that they may potentially be applied as skin care...
Here we present a new drug delivery system based on xanthan esterified with acrylic acid. This material served as matrix for the incorporation of bioactive substances antimicrobial and anti-inflammatory properties. The materials were characterized by Fourier Transform Infrared Spectroscopy (FTIR), Nuclear Magnetic Resonance (NMR) Scanning Electron Micrography (SEM). Mechanical strength tests showed substantial improvement in resilience flexibility polymer modified esterification under...
Heparin (Hep), with its anticoagulant activity, antiangiogenic and apoptotic effects, growth factor binding, plays an important role in various biological processes. Formulations as drug delivery systems protect limit the potential side effects of faulty administration. The objective this study was to develop novel xanthan-based materials a carrier for heparin. exhibited remarkable elastic behavior toughness without any crack development within network, which also support their application...