Shirley Lewis

ORCID: 0000-0001-5306-1649
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About
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Research Areas
  • Advanced Radiotherapy Techniques
  • Head and Neck Cancer Studies
  • Colorectal and Anal Carcinomas
  • Management of metastatic bone disease
  • Endometrial and Cervical Cancer Treatments
  • Oral health in cancer treatment
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cancer Genomics and Diagnostics
  • Colorectal Cancer Surgical Treatments
  • Gastric Cancer Management and Outcomes
  • Lung Cancer Diagnosis and Treatment
  • Advances in Oncology and Radiotherapy
  • Pancreatic and Hepatic Oncology Research
  • Radiation Therapy and Dosimetry
  • Esophageal Cancer Research and Treatment
  • Cancer survivorship and care
  • Breast Cancer Treatment Studies
  • Brain Metastases and Treatment
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Economic and Financial Impacts of Cancer
  • COVID-19 and healthcare impacts
  • Spinal Fractures and Fixation Techniques
  • Gallbladder and Bile Duct Disorders
  • Glioma Diagnosis and Treatment
  • Spine and Intervertebral Disc Pathology

Manipal Academy of Higher Education
2020-2025

Kasturba Medical College, Manipal
2015-2025

University of Huddersfield
2024

Max Super Speciality Hospital
2023

University Health Network
2014-2022

University of Toronto
2014-2022

Princess Margaret Cancer Centre
2022

Tata Memorial Hospital
2014-2021

Homi Bhabha National Institute
2019-2021

Melaka Manipal Medical College
2019

Abstract Quality attributes in health care setting include safety, effectiveness, patient centeredness, timeliness, efficiency, and equity. of outcomes depend not only on the clinical interactions between clinicians patients but also effective alignment integration team efforts, logistics, processes. The National Cancer Grid (NCG), with its mandate to facilitate promote quality standards across India, facilitated improvement (QI) training as a key initiative order develop competencies within...

10.1055/s-0045-1806837 article EN cc-by Indian Journal of Medical and Paediatric Oncology 2025-03-25

Spiritual well-being and fatigue are key parameters in assessing health related quality of life that determine treatment tolerance, outcomes reflect patient's coping ability the illness-wellness disease trajectory.A total 200 patients on active cancer were enrolled to study. Functional assessment chronic illness therapy-spirituality (FACIT-Sp) FACIT-Fatigue scales used assess spiritual scores during their treatment. Data analyzed using one-way analysis variance bivariate relationships...

10.4103/0973-1482.138125 article EN Journal of Cancer Research and Therapeutics 2014-01-01

There are various drugs tried for relieving pain associated with radiation-induced mucositis. This paper aims to study role of honey in due radiation induced mucositis head and neck cancer patients receiving concomitant chemoradiation.A randomized controlled trial on 78 subjects (40 test group 38 control group) was undertaken the analgesic effect honey, but analysis 69 done as nine (four five were lost follow-up or left treatment between study. All advised do salt-soda benzydamine mouth...

10.4103/0973-1075.164892 article EN Indian Journal of Palliative Care 2015-01-01

Distress is commonly seen in head and neck cancer patients undergoing radiotherapy. Causal factors of distress are multifactorial; which encompasses physical, psychological, spiritual, existential with complex interrelationship among the factors.Thirty radiotherapy were included study. Patients screened for pain scores, physical psychological symptoms, spiritual emotional distress.Significant increasing trend score, total number symptoms during 2(nd) week, 4(th) on completion treatment (all...

10.4103/0973-1075.116703 article EN Indian Journal of Palliative Care 2013-01-01

Abstract Background Women who use or are in treatment for drug during the perinatal period often have complex needs and presenting comorbidity. opioids pregnancy, their infants, experience poor outcomes. Drug by women pregnancy is a public health priority. This scoping review aimed to (1) map clinical guidelines, protocols good practice guidance across UK period, (2) identify recommended best social care optimising outcomes reducing inequalities these (3) potential gaps within guidance....

10.1186/s12884-023-06172-6 article EN cc-by BMC Pregnancy and Childbirth 2024-01-25

Introduction Neoadjuvant chemotherapy (NACT) is considered the current standard for locally advanced gallbladder cancer (GBC). There no consensus on optimal neoadjuvant approach. A pilot study from our institution has shown improved overall survival (OS) and progression-free (PFS) with chemoradiation (NACRT). The present randomised phase III trial designed to compare NACRT NACT alone will test superiority of in terms tumour downstaging improvement OS. Methods analysis Patients biopsy-proven...

10.1136/bmjopen-2018-028147 article EN cc-by-nc BMJ Open 2019-06-01

Fiducial markers are utilized for image guided radiotherapy (IGRT) alignment during the delivery of liver stereotactic body radiosurgery (SBRT). There limited data demonstrating impact matching fiducials on accuracy SBRT. This study quantifies benefit fiducial-based and improvements in inter-observer reliability. Nineteen patients with 24 lesions were treated Target localization was performed using fiducial cone-beam computed tomography (CBCT). Each CBCT procedure retrospectively realigned...

10.3390/curroncol30050382 article EN cc-by Current Oncology 2023-05-16

Palliation of dysphagia is a challenge in advanced esophageal cancer. The addition external beam radiotherapy (EBRT) to intraluminal brachytherapy (ILBT) has shown significant improvement relief and symptom scores. aim the present study was evaluate efficacy combined use ILBT EBRT.The medical records 148 patients with advanced/metastatic cancer were screened from January 2008 April 2014, 74 found eligible for analysis. All received two fractions 8 Gy each ILBT, followed by EBRT. Patients...

10.5114/jcb.2015.56765 article EN cc-by-nc-sa Journal of Contemporary Brachytherapy 2015-01-01

To estimate the prevalence of baseline clinically significant distress (distress score ≥ 4) in head and neck cancer patients planned treated with radical intent radiotherapy using National Comprehensive Cancer Network Distress Thermometer (DT) assess factors predictive distress.Cross-sectional study.This was a cross-sectional study evaluating 600 undergoing radiation therapy. The DT used to screen for at before radiotherapy.The median entire cohort 4 interquartile range (IQR) (IQR: 3-5), 340...

10.1002/lary.29491 article EN The Laryngoscope 2021-03-15

To report acute hematological toxicity (HT) in patients receiving post-operative bowel sparing intensity-modulated radiotherapy (IMRT) and cisplatin its dosimetric predictors.Clinical database of Phase III trial (NCT01279135), that randomized to conformal or intensity modulated radiation therapy, was searched select patient strata received IMRT (50 Gy/25#/5 wks) concurrent (40 mg m-2). Pelvic bone marrow (BM) retrospectively delineated two sets: whole (WB), freehand (FH) inner cavity bone....

10.1259/bjr.20180005 article EN British Journal of Radiology 2018-09-04

The rising cost of cancer treatment causes out-of-pocket spending among patients or caregivers in lower-middle-income countries, resulting acute misery and insolvency. This study aimed to assess the financial toxicity associated with coping strategies for adopted a tertiary care center.

10.1200/go.23.00397 article EN cc-by-nc-nd JCO Global Oncology 2024-07-01

Background and Purpose: Although there is a strong biological rationale to electively treat the pelvic nodes during bladder preservation, its clinical benefit uncertain. This may be explained by incidental dose received nodal regions when treating alone. study was conducted investigate doses different alone treated standard conformal radiotherapy. Methods Materials: The computed tomography data sets of 20 patients with node-negative muscle-invasive cancer in preservation protocol were...

10.1177/1533034617691409 article EN cc-by-nc Technology in Cancer Research & Treatment 2017-02-07
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