Functional magnetic resonance imaging (MRI) showed that the superior temporal and occipital cortex are involved in multisensory integration. Probabilistic fiber tracking based on diffusion-weighted MRI suggests processing is supported by white matter connections between auditory lobe. Here, we present a combined functional probabilistic study reveals mechanisms remained undetected either technique alone. Ten healthy participants passively observed visually presented lip or body movements,...

Patients with age-related macular degeneration (AMD) or hereditary dystrophies (JMD) rely on an efficient use of their peripheral visual field. We trained eight AMD and five JMD patients to perform a texture-discrimination task (TDT) at preferred retinal locus (PRL) used for fixation. Six training sessions approximately one hour duration were conducted over period 3 weeks. Before, during after twelve age-matched controls (the data from two had be discarded later) took part in three...

Introduction Macular degeneration (MD) can cause a central visual field defect. In previous study, we found volumetric reductions along the entire pathways of MD patients, possibly indicating inactive neuronal tissue. This may have important implications. particular, new therapeutic strategies to restore retinal function rely on intact and cortex reestablish function. Here reanalyze data our study using surface-based morphometry (SBM) rather than voxel-based (VBM). help determine robustness...

Patients with age-related macular degeneration (AMD) are reliant on their peripheral visual field. Oculomotor training can help them to find the best area intact retina and efficiently stabilize eccentric fixation. In this study, nine patients AMD were trained over a period of 6 months using oculomotor protocols improve fixation stability. They followed an additional months, where they completed auditory memory as sham training. cross-over design five started four Seven healthy age-matched...

Abstract Multisensory integration assists us to identify objects by providing multiple cues with respect object category and spatial location. We used a semantic audiovisual matching task determine the effect of congruency on response behavior fMRI brain activation. Fifteen subjects responded in four‐alternative paradigm, which visual quadrant contained best matched sound presented. Realistic sounds based head‐related transfer functions were presented binaurally simulated source...

Aging and central vision loss are associated with cortical atrophies, but little is known about the relationship between thinning underlying cellular structure. We compared macro- micro-structure of gray superficial white matter 38 patients juvenile (JMD) or age-related (AMD) macular degeneration healthy humans (19–84 years) by multimodal MRI including diffusion-tensor imaging (DTI). A factor analysis showed that thickness, tissue-dependent measures, DTI-based measures were sensitive to...

In patients with central visual field scotomata a large part of cortex is not adequately stimulated.We investigated evidence for possible upregulation in cortical responses 22 (8 females, 14 males; mean age 41.5 years, range 12-65 years) loss due to hereditary retinal dystrophies (Stargardt's disease, other forms macular and cone-rod dystrophy) compared their results those age-matched controls (11 11 age, 42.4 range, 13-70 years).Using functional magnetic resonance imaging (fMRI) we recorded...

In patients with central visual field scotomata, a large part of cortex is not adequately stimulated. Patients often use new eccentric fixation area on intact peripheral retina ("preferred retinal locus"-PRL) that functions as pseudo-fovea. We used functional magnetic resonance imaging (fMRI) to examine whether stimulating this pseudo-fovea leads increased activation or altered patterns in comparison comparable the opposite hemifield (OppPRL).Nineteen binocular scotomata caused by hereditary...

We manipulated the sense of body ownership with Rubber Hand Illusion (RHI) to determine if perception a potentially painful threat rubber hand can modify mechanical pain threshold (MPT). Simultaneous tactile stimulation subject's concealed and appropriately positioned visible generated illusion false ownership. The MPT was recorded on left subjects before after induction RHI, as well during phase in which model pricked sharp knife or touched by blunt handle. results indicate that RHI could...

Purpose: One of the diagnostic features visual crowding, radial–tangential anisotropy, has been observed both in behavioral experiments as well responses blood-oxygenation-level-dependent (BOLD) functional magnetic resonance imaging (fMRI) signal. As shown previously, crowding is stronger for radially arranged flankers, and this tendency reflected BOLD signal suppression. In current study, we examined effect practice on neural correlates crowding. We expected that training a task would cause...

In addition to gustatory, olfactory and somatosensory input, visual information plays a role in our experience of food drink. We asked whether colour this context has an effect at the perceptual level via multisensory integration or if higher cognitive factors are involved. Using articulatory suppression task, comparable Stevenson Oaten, processes should be interrupted during flavour discriminatory so that any residual effects would traceable low-level integration. Subjects judged...

A laboratory experiment was conducted to determine the maximum speeds of robot arm motion considered by subjects as safe for human operators working in a close proximity robot's envelope. Twenty-nine college students (16 males and 13 females) participated study monitors simulated assembly tasks performed two industrial robots different size work capabilities. The results show that speed selection process depends on physical its initial at start adjustment process. Subjects selected higher...

Functional magnetic resonance imaging (fMRI) is a valuable tool in the clinical routine of neurosurgery when planning surgical interventions and assessing risk postoperative functional deficits. Here, we examined how presence brain tumor or lesion area occipital lobe affects results fMRI retinotopic mapping. data were evaluated on retrospectively selected sample 12 patients with tumors, 7 lesions 19 control subjects. Analyses cortical activation, percent signal change, cluster size activated...

Retinal diseases like age-related macular degeneration (AMD) or hereditary juvenile dystrophies (JMD) lead to a loss of central vision. Many patients compensate for this with pseudo fovea in the intact peripheral retina, so-called “preferred retinal locus” (PRL). How extensive eccentric viewing associated vision (CVL) affects brain structures responsible visual perception and visually guided eye movements remains unknown. CVL results reduction cortical gray matter “lesion projection zone”...

Visual crowding refers to the impairment of recognizing peripherally presented objects flanked by distractors. Crowding effects, exhibiting a certain spatial extent between target and flankers, can be reduced perceptual learning. In this experiment, we investigated learning-induced reduction in normally sighted participants tested if learning on one optotype (Landolt-C) transfers another (Tumbling-E) or vice versa. Twenty-three (18–42 years) trained task right-upper quadrant (target at 6.5...

This study aimed to investigate the impact of eccentric-vision training on population receptive field (pRF) estimates provide insights into brain plasticity processes driven by practice. Fifteen participants underwent functional magnetic resonance imaging (fMRI) measurements before and after behavioral a visual crowding task, where relative orientation opening (gap position: up/down, left/right) in Landolt C optotype had be discriminated presence flanking ring stimuli. Drifting checkerboard...

Previous functional magnetic resonance imaging (MRI) found various brain areas in the temporal and occipital lobe involved integrating auditory visual object information. Fiber tracking based on diffusion-weighted MRI suggested neuroanatomical connections between cortex sub-regions of lobe. However, relationship activity white-matter tracks remained unclear. Here, we combined probabilistic order to reveal structural related auditory–visual perception. Ten healthy people were examined by MRI....