A5008864933- Laser-Plasma Interactions and Diagnostics
- Laser Design and Applications
- Laser-induced spectroscopy and plasma
- Advancements in Transdermal Drug Delivery
- Nuclear Physics and Applications
- Bee Products Chemical Analysis
- Laser-Matter Interactions and Applications
- Atomic and Subatomic Physics Research
- Orbital Angular Momentum in Optics
- Advanced Fiber Laser Technologies
- Gyrotron and Vacuum Electronics Research
- Quantum, superfluid, helium dynamics
- Terahertz technology and applications
- 3D Printing in Biomedical Research
- Dermatology and Skin Diseases
- Spectroscopy and Laser Applications
- Solid State Laser Technologies
- Mass Spectrometry Techniques and Applications
- Plasma Diagnostics and Applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Nonlinear Optical Materials Studies
- High-pressure geophysics and materials
- Particle accelerators and beam dynamics
- Microfluidic and Capillary Electrophoresis Applications
- Laser Material Processing Techniques
Optical Sciences (United States)
2016-2019
University of Michigan–Ann Arbor
2012-2019
Cockcroft Institute
2018
University of York
2018
Rutherford Appleton Laboratory
2018
Imperial College London
2018
TIFR Centre for Interdisciplinary Sciences
2018
Tata Institute of Fundamental Research
2018
Raja Ramanna Centre for Advanced Technology
2018
Deutsches Elektronen-Synchrotron DESY
2018
We describe the use of a genetic algorithm to apply active feedback laser wakefield accelerator at higher power (10 TW) and lower repetition rate (5 Hz) than previous work. The temporal shape drive pulse was adjusted automatically optimize properties electron beam. By changing software configuration, different could be improved. This included total accelerated charge per bunch, which doubled, average energy, increased from 22 27 MeV. Using experimental measurements directly provide allows...
We describe how active feedback routines can be applied at limited repetition rate (5 Hz) to optimize high-power $>10$ TW) laser interactions with clustered gases. Optimization of x-ray production from an argon cluster jet, using a genetic algorithm, approximately doubled the measured energy through temporal modification 150 mJ driving pulse. This approach achieved increased radiation yield exploration multi-dimensional parameter space, without requiring detailed priori knowledge complex...
We have investigated a new micro drug jet injector using laser pulse energy. An infrared beam of high energy (∼3 J/pulse) is focused inside driving fluid in small chamber. The then induces various releasing processes, and generates fast microjets through micronozzle. elastic membrane this system plays an important role transferring mechanical pressure protecting from heat release. In paper, we offer the sequential images microjet generation taken by speed camera as evidence multiple...
We demonstrate a repetitive, high flux, short-pulsed laser-driven neutron source using heavy-water jet target. measure generation at 1/2 kHz repetition rate several-mJ pulse energies, yielding time-averaged flux of 2 × 105 neutrons s−1 (into 4π steradians). Deuteron spectra are also measured in order to understand characteristics. Analyses time-of-flight indicate that two separate populations neutrons, 'prompt' and 'delayed', generated different locations. Gamma-ray emission from capture...
Using several-mJ energy pulses from a high-repetition rate (1/2 kHz), ultrashort (35 fs) pulsed laser interacting with ∼10 μm diameter stream of free-flowing heavy water (D2O), we demonstrate 2.45 MeV neutron flux 105/s. Operating at high intensity (of order 1019 W/cm2), pulse is efficiently absorbed in the pre-plasma, generating energetic deuterons. These collide deuterium nuclei both bulk target and large volume low density D2O vapor surrounding to generate neutrons through d(d,n)3He...
We apply active feedback optimization methods to pyroelectric measurements of a THz signal generated by four wave mixing in air using 1 mJ 12 mJ, 35 fs laser pulses operating at kHz repetition rate. A genetic algorithm, the as figure merit, determines voltage settings deformable mirror and results up 6 fold improvement compared with optimized for best focus. It is possible optimize different generation processes this technique.
레이저 기반의 무바늘 액체 약물전달장치는 계속해서 개발되어왔다. 빔이 고무 챔버 내부의 액체에 모이게 된다. 초점이 맞춰진 빔은 공기방울을 생성시키고 급격히 팽창하게 밀봉된 안쪽에서의 급격한 부피변화는 액체약물을 마이크로 노즐을 통해 빠르게 밀어내어 약물젯을 생성한다. 노즐의 출구지름은 100 ㎛ 이하이며 본 연구팀은 생성된 약물젯의 속도가 인체의 연조직으로 침투시키기에 충분함을 확인하였다. 이 실험에서는 사람의 혈전을 모사한 무게 비 5%의 젤라틴 수용액을 냉각시킨 샘플과 돼지 지방층을 사용하여 침투실험을 수행하였다.
Views Icon Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Twitter Facebook Reddit LinkedIn Tools Reprints and Permissions Cite Search Site Citation Jack J. Yoh, Hun-jae Jang, Mi-ae Park, Tae-hee Han, Jung-moo Hah; A laser syringe aimed at delivering drug into the outer layer of human skin. AIP Conference Proceedings 30 July 2012; 1464 (1): 524–531. https://doi.org/10.1063/1.4739906 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends...
We present results from experimental investigations to generate a high flux source of energetic neutrons using short pulse rep rate laser system. Interactions the with heavy water stream target allowed generation ~105 neutrons/second at an energy ~2.45 MeV. used liquid scintillators shape analysis along bubble detectors confirm neutron production. Further optimization as well increase in such systems has potential enable development driven portable source.