А. В. Смирнов

ORCID: 0000-0001-5361-8232
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About
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Research Areas
  • Enzyme function and inhibition
  • Plasma Diagnostics and Applications
  • Protist diversity and phylogeny
  • Material Properties and Applications
  • Chemical Reactions and Mechanisms
  • Synthesis and Catalytic Reactions
  • Industrial Engineering and Technologies
  • Engineering and Environmental Studies
  • Metallurgical Processes and Thermodynamics
  • Diverse Industrial Engineering Technologies
  • Cosmology and Gravitation Theories
  • Microbial Community Ecology and Physiology
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Engineering Technology and Methodologies
  • Cholinesterase and Neurodegenerative Diseases
  • Engineering Diagnostics and Reliability
  • Particle accelerators and beam dynamics
  • Plasma Applications and Diagnostics
  • Laser Design and Applications
  • Iron and Steelmaking Processes
  • Food Industry and Aquatic Biology
  • Magnetic confinement fusion research
  • Material Properties and Failure Mechanisms
  • Black Holes and Theoretical Physics
  • Synthesis and Characterization of Heterocyclic Compounds

All-Russian Research Institute Fisheries and Oceanography
2019-2025

Volgograd State Medical University
2013-2025

Vilnius University
2014-2025

Dagestan State University
2024-2025

Russian Academy of Sciences
2011-2024

Czech Academy of Sciences, Institute of Geology
2024

St Petersburg University
2014-2024

Institute for Nuclear Research
2005-2024

State Research Center of the Russian Federation
2024

Peter the Great St. Petersburg Polytechnic University
2011-2024

Abstract. This revision of the classification unicellular eukaryotes updates that Levine et al. (1980) for protozoa and expands it to include other protists. Whereas previous was primarily incorporate results ultrastructural studies, this incorporates from both research since 1980 molecular phylogenetic studies. We propose a scheme is based on nameless ranked systematics. The vocabulary taxonomy updated, particularly clarify naming groups have been repositioned. recognize six clusters may...

10.1111/j.1550-7408.2005.00053.x article EN Journal of Eukaryotic Microbiology 2005-10-01

Abstract This revision of the classification eukaryotes, which updates that Adl et al. [ J. Eukaryot. Microbiol . 52 (2005) 399], retains an emphasis on protists and incorporates changes since 2005 have resolved nodes branches in phylogenetic trees. Whereas previous was successful re‐introducing name stability to classification, this provides a for lineages were then still unresolved. The supergroups withstood hypothesis testing with some modifications, but despite progress, problematic at...

10.1111/j.1550-7408.2012.00644.x article EN Journal of Eukaryotic Microbiology 2012-09-01

Abstract This revision of the classification eukaryotes follows that Adl et al., 2012 [ J. Euk. Microbiol . 59(5)] and retains an emphasis on protists. Changes since have improved resolution many nodes in phylogenetic analyses. For some clades even families are being clearly resolved. As we had predicted, environmental sampling intervening years has massively increased genetic information at hand. Consequently, discovered novel clades, exciting new genera uncovered a massive species level...

10.1111/jeu.12691 article EN cc-by Journal of Eukaryotic Microbiology 2018-09-26

We report picosecond time-resolved x-ray diffraction from the myoglobin (Mb) mutant in which Leu 29 is replaced by Phe (L29Fmutant). The frame-by-frame structural evolution, resolved to 1.8 angstroms, allows one literally “watch” protein as it executes its function. Time-resolved mid-infrared spectroscopy of flash-photolyzed L29F MbCO revealed a short-lived CO intermediate whose 140-ps lifetime shorter than that found wild-type factor 1000. electron density maps unveil transient...

10.1126/science.1078797 article EN Science 2003-06-19

A random flow generation (RFG) technique is presented, which can be used for initial/inlet boundary in LES (Large-Eddy-Simulations) or particle tracking LES/RANS (Reynolds-Averaged Navier-Stokes) computations of turbulent flows. The based on previous methods synthesizing divergence-free vector fields from a sample Fourier harmonics and allows to generate non-homogeneous anisotropic field representing velocity fluctuations. It was validated the cases layer flat plate Applications are considered.

10.1115/1.1369598 article EN Journal of Fluids Engineering 2001-02-16

A rotation-curvature correction suggested earlier by Spalart and Shur (1997, “On the Sensitization of Turbulence Models to Rotation Curvature,” Aerosp. Sci. Technol., 1(5), pp. 297–302) for one-equation Spalart–Allmaras turbulence model is adapted shear stress transport model. This new version (SST-CC) has been extensively tested on a wide range both wall-bounded free turbulent flows with system rotation and/or streamline curvature. Predictions SST-CC are compared available experimental...

10.1115/1.3070573 article EN Journal of Turbomachinery 2009-07-02

Assembling the global eukaryotic tree of life has long been a major effort Biology. In recent years, pushed by new availability genome-scale data for microbial eukaryotes, it become possible to revisit many evolutionary enigmas. However, some most ancient nodes, which are essential inferring stable tree, have remained highly controversial. Among other reasons, lack adequate genomic datasets key taxa prevented robust reconstruction early diversification events. this context, centrohelid...

10.1098/rspb.2015.2802 article EN Proceedings of the Royal Society B Biological Sciences 2016-01-27

Amoebozoa is the eukaryotic supergroup sister to Obazoa, lineage that contains animals and Fungi, as well their protistan relatives, breviate apusomonad flagellates. extraordinarily diverse, encompassing important model organisms significant pathogens. Although amoebozoans are integral global nutrient cycles present in nearly all environments, they remain vastly understudied. We a robust phylogeny of based on broad representative set taxa phylogenomic framework (325 genes). By sampling 61...

10.1093/molbev/msx162 article EN cc-by-nc Molecular Biology and Evolution 2017-05-12

the origin of echolocation and flight in bats. Nature 403:188– 192. van Rheede, T., T. Bastiaans, D. N. Boone, S. B. Hedges, W. de Jong, O. Madsen. 2006. The platypus its place: nuclear genes indels confirm sister group relation monotremes therians. Mol. Biol. Evol. 23:587–597. Waddell, P. J., H. Kishino, R. Ota. 2001. A phylogenetic foundation for comparative mammalian genomics. Genome Informatics 12:141– 154. Okada, M. Hasegawa. 1999. Towards resolving interordinal relationships placental...

10.1080/10635150701494127 article EN Systematic Biology 2007-07-28

10.1134/s0965542513120129 article EN Computational Mathematics and Mathematical Physics 2013-12-01

Human carbonic anhydrase IX (CA IX) is highly expressed in tumor tissues, and its selective inhibition provides a potential target for the treatment of numerous cancers. Development potent, inhibitors against this remains an unmet need anticancer therapeutics. A series fluorinated benzenesulfonamides with substituents on benzene ring was designed synthesized. Several these exhibited potent profile CA IX. Three fluorine atoms significantly increased affinity by withdrawing electrons lowering...

10.1021/jm501003k article EN Journal of Medicinal Chemistry 2014-10-30

The lifetimes of fluorescent components matrix NADH in isolated porcine heart mitochondria were investigated using time-resolved fluorescence spectroscopy. Three distinct resolved: 0.4 (63%), 1.8 (30%), and 5.7 (7%) ns (% total NADH). lifetime the emission wavelength short component consistent with free NADH. In addition to their longer lifetimes, remaining pools also had a blue-shifted spectrum immobilized On basis frequency data, contributed >80% fluorescence. steady-state kinetics...

10.1021/bi0485124 article EN Biochemistry 2005-01-25

This paper describes a novel idea of fine-grained fully-active plastic scintillator detector made many optically independent $1\times1\times1~\text{cm}^3$ cubes with readout on three orthogonal projections by wavelength shifting fibers. The original purpose this is to serve as an active neutrino target for the detection, measurement and identification final state particles down few tenths MeV kinetic energies. views well fine granularity ensure powerful localization deposited energy combined...

10.1088/1748-0221/13/02/p02006 article EN Journal of Instrumentation 2018-02-02

New species Scoliorhapis stepanovi has been collected from depths of 10-23 m on the sandy bottom Avacha Bay (east coast Kamchatka), Paramushir Island (North Kuril Islands), and Matua (Middle Islands). It is unique in having sigmoid ossicles body wall with points at both ends (without an open-eye, two lying a perpendicular plane). Such sigmoids do not occur any other taeniogyrinid species. The two-pointed are 80-115 µm length, scattered clustered. Probably underdeveloped typical open-eye. In...

10.11646/zootaxa.4337.4.7 article EN Zootaxa 2017-10-20

The current study was performed for the experimental modeling of cyclic steam-air injection in a heavy oil reservoir model dual porosity presence nickel-based catalyst situ upgrading enhanced by simultaneous hydrogen generation. research realized combustion tube setup with sandpack core under conditions due to consistent air followed (ISC) and steam (water) injection. As result, original upgraded regarding fractional composition properties. In addition, simulated heterogeneity stimulation...

10.3390/catal13081172 article EN Catalysts 2023-07-30
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