- Obesity, Physical Activity, Diet
- Birth, Development, and Health
- Child and Adolescent Health
- Nutrition and Health Studies
- Regulation of Appetite and Obesity
- Protein Structure and Dynamics
- Diabetes Management and Research
- Nutritional Studies and Diet
- Adolescent and Pediatric Healthcare
- Children's Physical and Motor Development
- Health and Lifestyle Studies
- Diet and metabolism studies
- Carbohydrate Chemistry and Synthesis
- Adipose Tissue and Metabolism
- Diabetes and associated disorders
- Chemical Synthesis and Analysis
- Biochemical Analysis and Sensing Techniques
- Childhood Cancer Survivors' Quality of Life
- Human Health and Disease
- Diet, Metabolism, and Disease
- Eating Disorders and Behaviors
- Global Health Care Issues
- Child Nutrition and Water Access
- Obesity and Health Practices
- Metabolism and Genetic Disorders
Rzeszów University
2016-2025
Jiangsu Province Hospital
2024
Instytut Lotnictwa
2024
Łukasiewicz Research Network
2024
Medical University of Vienna
2024
Leibniz Institute for Prevention Research and Epidemiology - BIPS
2024
University Medical Center Groningen
2024
University of Crete
2024
Ruhr University Bochum
2024
Consiglio per la ricerca in agricoltura e l’analisi dell’economia agraria
2024
Significance Invading pathogens and other danger-associated signals are recognized by the innate immune system. Subsequently, eukaryotic protein ASC [apoptosis-associated speck-like containing a caspase-recruitment domain (CARD)] assembles to long filaments, which might serve amplify signal activate an inflammatory response. We have determined structure of mouse filament at atomic resolution. The pyrin forms helical core, CARD, thus far elusive experimental observation, is flexibly unfolded...
Abstract In Bacteroidetes, one of the dominant phyla mammalian gut, active uptake large nutrients across outer membrane is mediated by SusCD protein complexes via a “pedal bin” transport mechanism. However, many features function in glycan remain unclear, including ligand binding, role SusD lid and size limit for substrate transport. Here we characterise β2,6 fructo-oligosaccharide (FOS) importing from Bacteroides thetaiotaomicron (Bt1762-Bt1763) to shed light on function. Co-crystal...
Tuberculosis vaccines (Bacillus Calmette-Guérin, BCG) were introduced 100 years ago and are still recommended by the World Health Organization to prevent disease. Studies have shown that BCG vaccination can stimulate non-specific immune responses reduce incidence of certain diseases. At beginning coronavirus disease 2019 (COVID-19) pandemic, it was hypothesised COVID-19 lower in countries with prevention. In an attempt verify this thesis, we conducted a multicenter, randomised, double-blind,...
Together we are strong: A new, robust method allows the measurement of residual chemical shift anisotropies for determination conformation and configuration molecules in organic solvents. The power is shown by example estrone 13-epi-estrone (see structures), where only combined use dipolar couplings leads to distinction two diastereomers. Detailed facts importance specialist readers published as "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset. They made...
Abstract Around one in ten adolescents suffer from chronic conditions and disabilities, the transition paediatric to adult care can be particularly challenging. Unplanned transfers complicate education, work health result patients being lost follow‐up, poor treatment adherence more frequent hospitalisation. The Adolescent Health Medicine Working Group of European Academy Paediatrics has developed a consensus statement for successful transition. Conclusion: This will help paediatricians,...
Conformation and dynamics of a chaperone-client interaction at the atomic level show basic underlying mechanism.
The chaperone Trigger Factor (TF) from Escherichia coli forms a dimer at cellular concentrations. While the monomer structure of TF is well known, spatial arrangement this dimeric storage form has remained unclear. Here, we determine its by combination high-resolution NMR spectroscopy and biophysical methods. symmetric head-to-tail dimer, where ribosome binding domain in contact with substrate domain, while peptidyl-prolyl isomerase contributes only slightly to affinity. highly dynamic, two...
The aim of this study was to evaluate the prevalence overweight, obesity and underweight in children from Ukraine. A cross-sectional performed on data collected a representative sample Ukraine (13,739 (boys 48%, girls 52%) aged 6.0-18.9 years). measurement body weight with medical scales height measured using stadiometer. Based results obtained, mass index (BMI) calculated. Three criteria were used define childhood underweight, overweight obesity: International Obesity Task Force (IOTF)...
Abstract Background The outbreak of the Covid-19 pandemic has created a number obstacles to daily functioning, which have led need for major changes in lifestyles. aim study was assess whether and what extent affected health behaviours young adults. Methods 506 people aged 18 34 ( $$ \overline{x} <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mover> <mml:mi>x</mml:mi> <mml:mo>¯</mml:mo> </mml:mover> </mml:math> =24.67 years ±4.23 years) who filled an online survey were...
Childhood obesity is one of the most important problems public health. Searching was conducted by using PubMed/MEDLINE, Cochrane Library, Science Direct, MEDLINE, and EBSCO databases, from January 2022 to June 2022, for English language meta-analyses, systematic reviews, randomized clinical trials, observational studies all over world. Five main topics were defined in a consensus join statement Polish Society Pediatrics, Pediatric Obesity, Endocrinology Diabetes Association Study on Obesity:...