A5056359451- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Child and Adolescent Health
- Childhood Cancer Survivors' Quality of Life
- Influenza Virus Research Studies
- Immunodeficiency and Autoimmune Disorders
- Acute Lymphoblastic Leukemia research
- Bacterial Infections and Vaccines
- Neonatal Respiratory Health Research
- Viral gastroenteritis research and epidemiology
- Nutrition and Health Studies
- Vaccine Coverage and Hesitancy
- Streptococcal Infections and Treatments
- Chronic Lymphocytic Leukemia Research
- Kawasaki Disease and Coronary Complications
- Polish Legal and Social Issues
- Hepatitis B Virus Studies
- Ethics and Legal Issues in Pediatric Healthcare
- Cervical Cancer and HPV Research
- Hepatitis Viruses Studies and Epidemiology
- Chemotherapy-induced cardiotoxicity and mitigation
- Thyroid Disorders and Treatments
- Family Support in Illness
- Pediatric Urology and Nephrology Studies
- Acute Myeloid Leukemia Research
Postgraduate School of Molecular Medicine
2015-2024
Centrum Medyczne Kształcenia Podyplomowego
2009-2024
Provincial Polyclinical Hospital in Toruń
2010-2022
Grochowski Hospital
2015-2022
Universidad Autónoma de Santo Domingo
2019
Medical University of Lodz
2016
Centralny Szpital Kliniczny
2013-2015
Szpital Kliniczny Dzieciątka Jezus
2015
Polskie Towarzystwo Gastroenterologii
2014
Institute for Postgraduate Medical Education
2012-2013
Tuberculosis vaccines (Bacillus Calmette-Guérin, BCG) were introduced 100 years ago and are still recommended by the World Health Organization to prevent disease. Studies have shown that BCG vaccination can stimulate non-specific immune responses reduce incidence of certain diseases. At beginning coronavirus disease 2019 (COVID-19) pandemic, it was hypothesised COVID-19 lower in countries with prevention. In an attempt verify this thesis, we conducted a multicenter, randomised, double-blind,...
Background: Global pediatric immunization programs with pneumococcal conjugate vaccines (PCVs) have reduced vaccine-type disease, but a substantial disease burden of non-PCV serotypes remains. Methods: This phase 3, randomized (1:1), double-blind study evaluated safety and immunogenicity 20-valent PCV (PCV20) relative to 13-valent (PCV13) in healthy infants. Participants received 2 infant doses toddler dose PCV20 or PCV13, diphtheria-tetanus-acellular pertussis combination vaccine at all...
Childhood obesity is one of the most important problems public health. Searching was conducted by using PubMed/MEDLINE, Cochrane Library, Science Direct, MEDLINE, and EBSCO databases, from January 2022 to June 2022, for English language meta-analyses, systematic reviews, randomized clinical trials, observational studies all over world. Five main topics were defined in a consensus join statement Polish Society Pediatrics, Pediatric Obesity, Endocrinology Diabetes Association Study on Obesity:...
Background: Respiratory syncytial virus (RSV) is an important cause of childhood hospitalizations. The aim the study was to estimate rates RSV-related hospitalizations in children aged less than 5 years Poland. Methods: This retrospective observational cohort based on data obtained from National Health Fund Poland regarding all acute respiratory tract infections and RSV-coded admissions (age < years) public hospitals between July 2015 June 2023. Patients were stratified following age...
During the winter months of 2020/2021 a wave multisystem inflammatory syndrome in children (MIS-C) emerged Poland. We present results nationwide register aiming to capture and characterise MIS-C with focus on severity determinants. The first Poland was notably high, hence our analysis involved 274 children. group 62.8% boys, median age 8.8 years. Besides one Asian, all were White. Overall, disease course not as severe previous reports, however. Pediatric intensive care treatment required for...
Pediatric inflammatory multisystem syndrome (PIMS) is a new entity in children, likely associated with previous coronavirus disease 19 (COVID-19) infection. Most of the reports about PIMS come from countries particularly hit by COVID-19 pandemic. Our aim was to investigate nature syndromes Poland (country low prevalence) and perceive emergence our country. On 25 May 2020, we launched nationwide survey children for retrospective (since 4 March 2020) prospective data collection. Up 28 July, 39...
The COVID-19 pandemic has been met with an unprecedented response from the scientific community leading to development, study, and authorization of vaccines antivirals, ultimately reducing impact SARS-CoV-2 on global public health. However, is far being eradicated, continues evolve, causes substantial health economic burdens. In this paper, we posit essential points its management during transition acute phase pandemic. As discussed, despite Omicron (sub)variant(s) causing clinically milder...
Abstract Background Clesrovimab is an investigational, long-acting monoclonal antibody (mAb) targeting site IV of the fusion protein for prevention RSV lower respiratory tract infection in infants. Methods This phase 2b/3 double-blind, randomized, placebo-controlled pivotal study enrolled healthy preterm and full-term infants birth to 1 year age entering their first season. Participants (pts) were randomized 2:1 receive clesrovimab (105 mg IM) or placebo on day 1. Safety tolerability a...
Although acute otitis media (AOM) remains a major public health problem worldwide and brings economic burden on care system caregivers, little information is available about its epidemiology in Eastern Europe. We conducted an epidemiological, prospective, observational, multi-centre cohort study (NCT01365390) five East European countries (Estonia, Lithuania, Poland, Romania Slovenia) between June 2011 January 2013 to determine the incidence clinical characteristics of AOM among children aged...
Prophylactic antipyretic use during pediatric vaccination is common. This study assessed whether paracetamol or ibuprofen prophylaxis interfere with immune responses to the 13-valent pneumococcal conjugate vaccine (PCV13) given concomitantly combined DTaP/HBV/IPV/Hib vaccine. Subjects received prophylactic at 0, 6–8, and 12–16 h after vaccination, 6–8 2, 3, 4, 12 months of age. At 5 13 months, were evaluated versus in controls who no prophylaxis. After infant series, recipients had lower...
Background: We evaluated an inactivated quadrivalent influenza vaccine (IIV4) in children 6–35 months of age a phase III, observer-blind trial. Methods: The aim this analysis was to estimate efficacy (VE) preventing laboratory-confirmed each 5 independent seasonal cohorts (2011−2014), as well impact on healthcare utilization 3 study regions (Europe/Mediterranean, Asia-Pacific and Central America). Healthy were randomized 1:1 IIV4 or control vaccines. VE estimated against confirmed by reverse...
Respiratory syncytial virus (RSV) contributes significantly to pediatric hospitalizations. An association between air pollution and an increased number of RSV cases has been suggested. We sought evaluate the short-term impact pollutants on hospitalizations in Polish children period 2010–2019. Daily concentrations PM10 PM2.5 (particulate matter with aerodynamic diameter less than or equal 10 μm 2.5 μm, respectively) nitrogen dioxide (NO2) were analyzed general regression models (GRM)...
Background: RSV often leads to hospitalization, and accurate knowledge of risk factors is crucial. Methods: We retrospectively analyzed laboratory-confirmed hospitalizations regarding pregnancy factors, birth status, cigarette smoke exposure, nutrition, social conditions, clinical presentation, severe disease defined as a need for passive oxygen therapy (pO2Tx), the presence pneumonia, respiratory failure, intensive care unit (ICU) transfer, prolonged hospitalization. Results: A univariate...
Community-acquired pneumonia (CAP) severely affects pediatric hospitalizations. This study assessed the contribution of CAP to hospitalizations, its etiology in relationship with age, and inflammatory markers. Between 2013 2018, 1064 patients were hospitalized diagnosed bacterial/possibly bacterial (BP), viral/possibly viral (VP) atypical (AP). The was confirmed using blood/pleural fluid culture/polymerase chain reaction (PCR), rapid antigen test/PCR nasopharyngeal swabs, or serological...
The aim of this study was to assess humoral response influenza vaccine in children with acute lymphoblastic leukemia.Studies were performed 25 patients previously vaccinated against (Group A) and 20 who had never been immunized before B). In Autumn, 1996, they subunit trivalent containing 15 microg hemagglutinin A/Singapore/6/86, A/Wuhan/359/95 B/Beijing(184/93. Antihemagglutinin (HI) antineuraminidase antibody titers determined immunization 3 weeks 6 months after vaccination by the...
Respiratory tract infections constitute the most frequent manifestation of X-linked agammaglobulinemia (XLA). There are not many papers elucidating gastrointestinal (GI) disorders, including inflammatory bowel disease (IBD), in such patients. The aim study was to evaluate occurrence disorders and IBD compared respiratory XLA individuals.Of 1563 patients with primary immunodeficiencies diagnosed Department Immunology, Children's Memorial Health Institute (CMHI), 66 boys had a provisional...