- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Influenza Virus Research Studies
- Bacterial Infections and Vaccines
- Helicobacter pylori-related gastroenterology studies
- Pneumonia and Respiratory Infections
- Gastrointestinal Bleeding Diagnosis and Treatment
- Asthma and respiratory diseases
- Bipolar Disorder and Treatment
- Respiratory and Cough-Related Research
- Schizophrenia research and treatment
- Respiratory viral infections research
- Vaccine Coverage and Hesitancy
- Gastrointestinal disorders and treatments
- Esophageal and GI Pathology
- Global Health Care Issues
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Hepatitis Viruses Studies and Epidemiology
- Adipokines, Inflammation, and Metabolic Diseases
- Viral gastroenteritis research and epidemiology
- Health Systems, Economic Evaluations, Quality of Life
- Infective Endocarditis Diagnosis and Management
- Treatment of Major Depression
- Pituitary Gland Disorders and Treatments
- Colorectal Cancer Screening and Detection
GlaxoSmithKline (Belgium)
2014-2022
AstraZeneca (Spain)
2007-2012
AstraZeneca (United Kingdom)
2011-2012
AstraZeneca (Brazil)
2012
Centro Nacional de Epidemiología
2011
Hospital General Universitario Morales Meseguer
2004-2010
The measurement of health-related quality life (HRQoL) is increasingly recognized as an important endpoint, a reflection the effects disease from patient perspective. Our aim was to evaluate factors determining HRQoL in patients with asthma, according EQ-5D questionnaire. Patients were included using multi-stage sampling, Primary Care clinics all Autonomous Communities Spain. were: over 18 years-old, confirmed diagnosis asthma for at least one year, and had visited Health Centre previous 2...
Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a common medical emergency associated with substantial morbidity and mortality. Despite advances in endoscopic pharmacological treatment during the past two decades, incidence of mortality NVUGIB has remained relatively constant.To report outcomes predictive factors for continuation/re-bleeding clinical practice different European countries.This observational, retrospective cohort study (NCT00797641; ENERGIB) was conducted Belgium,...
Although acute otitis media (AOM) remains a major public health problem worldwide and brings economic burden on care system caregivers, little information is available about its epidemiology in Eastern Europe. We conducted an epidemiological, prospective, observational, multi-centre cohort study (NCT01365390) five East European countries (Estonia, Lithuania, Poland, Romania Slovenia) between June 2011 January 2013 to determine the incidence clinical characteristics of AOM among children aged...
Protection against vaccine-preventable diseases is especially relevant in older adults due to age-related decline immunity (immunosenescence). However, adult vaccination remains a challenge with overall low coverage rates, which has an impact on both the patients who have these and health care system terms of resource use costs derived. This study aimed estimate direct economic herpes zoster, pneumococcal disease, influenza pertussis Spanish 45 years older.Data from 2015 were extracted two...
Physicians involved in primary prevention are key players CVD risk control strategies, but the expected reduction that would be obtained if all patients attending care had their factors controlled according to current guidelines is unknown. The objective of this study was estimate excess attributable, firstly, presence and, secondly, lack these across Europe. Cross-sectional using data from European Study on Cardiovascular Risk Prevention and Management Daily Practice (EURIKA), which...
Objective: The aim of this study was to assess the long-term impact quetiapine on sexual functioning patients with schizophrenia treated in a real practice setting. Methods: This multicenter, noncomparative, open-label, and naturalistic conducted outpatients diagnosis or schizophreniform disorder as defined by Diagnostic Statistical Manual Mental Disorders, Fourth Edition. Patients were evaluated at baseline, day 15, end months 1, 3, 6 using Brief Psychiatry Rating Scale, Clinical Global...
Objective. To study asthma-related absenteeism in the asthmatic population Spain and to identify some risk factors for absenteeism. Methods. A cross-sectional was performed on patients who had been diagnosed with asthma primary care setting at least 1 year before start of this study. questionnaire designed that included socio-demographic clinical variables. The time absent from work previous self-reported by patients. Results. More than 25% took sick leave during year. Visits a general...
This multi-center, hospital-based observational study determined the seroprevalence of pertussis antibodies amongst healthcare professionals from three different hospitals in Spain to ascertain health status attending susceptible groups who are at risk contracting and transmitting pertussis.Medical were recruited for this (NCT01706224). Serum samples subjects assessed anti-pertussis by ELISA. The percentage positive age-strata, gender, vaccination status, professional level (physicians,...
Although some studies indicate that bipolar disorder causes high health care resources consumption, no study is available addressing a cost estimation of in Spain. The aim this observational was to evaluate healthcare resource utilization and the associated direct patients with manic episodes Spanish setting. Retrospective descriptive carried out consecutive sample DSM-IV diagnosis type I or without psychotic symptoms, aged 18 years older, who were having an active episode at time inclusion....
Pertussis (whooping cough) is well known to be underreported, particularly among adults, who can act as an infectious reservoir, potentially putting susceptible newborns at risk of serious illness. The purpose this study was estimate the seroprevalence pertussis in adults Hungary. This epidemiological, cross-sectional conducted five general practitioners' practices Serum anti-pertussis toxin immunoglobulin G (anti-PT IgG) antibody levels were analyzed using enzyme-linked immunosorbent assay....
Objective:To describe the management of gastro-oesophageal reflux disease (GERD) in primary care, as part RANGE (Retrospective ANalysis GERD) study.Methods:Over 4 months, at 134 care practices six European countries, 12 815 patients consulted for GERD-related reasons. A random selection these was invited to enter study. Data were then collected retrospectively (from initial consultation) and prospectively a follow-up visit). This included information on GERD diagnosis, symptoms...
Response to treatment among primary care patients with gastro-oesophageal disease (GERD) is variable.The GERD Management Project (GMP) evaluated the effectiveness of a structured management approach vs. standard (usual care).Data from five cluster-randomised clinical trials in adult symptoms were pooled. The pathway was based on self-administered Questionnaire (GerdQ) and compared treatment.1734 enrolled (structured treatment, n=834; n=900). difference mean GerdQ score change baseline...
Objective. To report on the primary care consultation rates and clinical characteristics of patients with gastro-oesophageal reflux disease (GERD) as part RANGE (Retrospective ANalysis GERD) observational study. Methods. was conducted at 134 centres across six European countries. All subjects who consulted their physician during a 4-month identification period were screened retrospectively. Those consulting for GERD-related reasons identified, randomly selected cohort underwent interview....
This multicentre, observational, prospective, nonrandomized study compared the effectiveness and tolerability of quetiapine risperidone in acute long-term treatment schizophrenia a clinical setting. Patients admitted to an unit with schizophrenia, schizophreniform or schizoaffective disorder (DSM-IV), who were prescribed (3 : 1 ratio) within first week treatment, according physician's usual practice, recruited. In total, 492 patients (quetiapine: 367; risperidone: 125) followed up at weeks...
To report on the primary care consultation rates and clinical characteristics of patients with gastro-oesophageal reflux disease (GERD) as part RANGE (Retrospective ANalysis GERD) observational study.RANGE was conducted at 134 centres across six European countries. All subjects who consulted their physician during a 4-month identification period were screened retrospectively. Those consulting for GERD-related reasons identified, randomly selected cohort underwent interview.Out 373,610...
Background: The measurement of health-related quality life (HRQoL) is increasingly recognized as an important endpoint, a reflection the effects disease from patient perspective. Our aim was to evaluate factors determining HRQoL in patients with asthma, according EQ-5D questionnaire. Methods: Patients were included using multi-stage sampling, Primary Care clinics all Autonomous Communities Spain. were: over 18 years-old, confirmed diagnosis asthma for at least one year, and had visited...