A5065065656- Cardiac pacing and defibrillation studies
- Bipolar Disorder and Treatment
- Cardiac electrophysiology and arrhythmias
- Adolescent and Pediatric Healthcare
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac Arrest and Resuscitation
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Coffee research and impacts
- Venous Thromboembolism Diagnosis and Management
- Dialysis and Renal Disease Management
- Iron Metabolism and Disorders
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiomyopathy and Myosin Studies
- Cardiac and Coronary Surgery Techniques
- Cardiac Health and Mental Health
- ECG Monitoring and Analysis
- Electroconvulsive Therapy Studies
- Schizophrenia research and treatment
- Blood transfusion and management
- Erythropoietin and Anemia Treatment
- Receptor Mechanisms and Signaling
- Family Caregiving in Mental Illness
- Sleep and Work-Related Fatigue
Johns Hopkins University
2012-2024
Johns Hopkins Medicine
2004-2023
NorthEast Regional Epilepsy Group
2016
Research Network (United States)
2016
University of Maryland, Baltimore
2014
MedStar Washington Hospital Center
2014
Virginia Commonwealth University Medical Center
2014
Background: Blacks have a higher incidence of out-of-hospital sudden cardiac death (SCD) in comparison with whites. However, the racial differences cumulative risk SCD and reasons for these not been assessed large-scale community-based cohorts. The objective this study is to compare lifetime among blacks whites, evaluate factors that may explain general population. Methods: This cohort 3832 11 237 whites participating Atherosclerosis Risk Communities Study (ARIC). Race was self-reported....
<h3>Background</h3>Extreme prolongation or reduction of the QT interval predisposes patients to malignant ventricular arrhythmias and sudden cardiac death, but association variations in within a reference range with mortality end points general population is unclear.<h3>Methods</h3>We included 7828 men women from Third National Health Nutrition Examination Survey. Baseline was measured via standard 12-lead electrocardiographic readings. Mortality were assessed through December 31, 2006 (2291...
Background:The risks associated with the use of combination aspirin and clopidogrel before surgery are incompletely understood.Pharmacologic suppression platelet function may increase risk postoperative infection by inhibiting hemostasis, immunity, or both. Methods:We performed a retrospective cohort study 1677 patients undergoing coronary artery bypass to determine relationship preoperative plus vs alone 30-day incidence surgical site bacteremia. Results:The cumulative at 30 days was 23.1%...
Background— Primary prevention implantable cardioverter defibrillators (ICDs) reduce all-cause mortality, but the benefits are heterogeneous. Current risk stratification based on left ventricular ejection fraction has limited discrimination power. We hypothesize that biomarkers for inflammation, neurohumoral activation, and cardiac injury can predict appropriate shocks mortality in patients with primary ICDs. Methods Results— The Prospective Observational Study of Implantable Cardioverter...
Abnormalities in the electrocardiographic QT interval duration have been associated with an increased risk of ventricular arrhythmias and sudden cardiac death. However, there is substantial uncertainty about effect modifiable factors such as coffee intake, cigarette smoking, alcohol consumption, physical activity on duration.We studied 7795 men women from Third National Health Nutrition Survey (NHANES III, 1988-1994). Baseline was measured standard 12-lead electrocardiogram. Coffee tea...
Physicians involved in primary prevention are key players CVD risk control strategies, but the expected reduction that would be obtained if all patients attending care had their factors controlled according to current guidelines is unknown. The objective of this study was estimate excess attributable, firstly, presence and, secondly, lack these across Europe. Cross-sectional using data from European Study on Cardiovascular Risk Prevention and Management Daily Practice (EURIKA), which...
To identify baseline patient characteristics associated with increased susceptibility to surgical site infection (SSI) after elective surgery.The Center for Medicare and Medicaid Services considers SSI be preventable through adherence current control practices; however, the etiology of wound is incompletely understood.Prospective cohort study involving patients undergoing cardiac, vascular, craniotomy, spinal surgery at 2 academic medical centers in Baltimore, MD. A comprehensive history was...
Disturbances in 25-hydroxyvitamin D, calcium, and phosphorus concentrations have been associated with increased risks of total cardiovascular mortality. It is possible that changes electrocardiographic QT interval duration may mediate these effects, but the association phosphorus, calcium has not evaluated general population samples. The objective study was to evaluate two large samples U.S. population. This included cross-sectional analyses Third National Health Nutrition Survey (NHANES...
Abstract Background Studies in bipolar disorder (BD) to date are limited their ability provide a whole-disease perspective - scope has generally been confined single disease phase and/or specific treatment. Moreover, most clinical trials have focused on the manic of disease, and not depression, which is associated with greatest burden. There few longitudinal studies covering both types patients BD (I II) whole course regardless patients' symptomatology. Therefore, Wide AmbispectiVE study...
Introduction Altered thyroid status exerts a major effect on the heart. Individuals with hypo- or hyperthyroidism showed various changes in electrocardiograms. However, little is known about how variations hormone levels within normal range affect electrical activities of heart general population. Methods and Results We conducted cross-sectional analysis 5,990 men women from Third National Health Nutrition Examination Survey. Serum total T4 was measured by immunoassay TSH chemiluminescent...
Introduction Individuals with systolic heart failure are at risk of ventricular arrhythmias and all-cause mortality. Little is known regarding the mechanisms underlying these events. We sought to better understand if oxylipins, a diverse class lipid metabolites derived from oxidation polyunsaturated fatty acids, were associated outcomes in recipients primary prevention implantable cardioverter defibrillators (ICDs). Methods Among 479 individuals PROSE-ICD study, baseline serum analyzed...
Blasco-Colmenares, Elena; Farag, Youssef M. K.; Zhao, Di; Guallar, Eliseo; Finkelstein, Fredric O. Author Information
Key Points In a large sample representative of the US adult noninstitutionalized population, among participants with CKD stages 3–5, anemia was associated significantly lower level physical activity. The presence and showed positive interaction on functioning outcomes. Among CKD, worse in patients compared those without anemia. Background is major public health problem worldwide. Anemia, frequent treatable complication decreased objective this study to evaluate joint association activity...
Cardiac resynchronization therapy (CRT) devices reduce mortality through pacing-induced cardiac and implantable cardioverter defibrillator (ICD) for ventricular arrhythmias (VAs). Whether certain factors can predict if patients will benefit more from implantation of CRT pacemakers (CRT-P) or defibrillators (CRT-D) remains unclear.We followed 305 primary prevention CRT-D recipients the two outcomes HF hospitalization ICD VAs. Serum biomarkers, electrocardiographic clinical variables were...