A5101943663- Bacterial Infections and Vaccines
- Vaccine Coverage and Hesitancy
- Pneumonia and Respiratory Infections
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cytomegalovirus and herpesvirus research
- Viral gastroenteritis research and epidemiology
- Pediatric health and respiratory diseases
- Asthma and respiratory diseases
- Herpesvirus Infections and Treatments
- Heparin-Induced Thrombocytopenia and Thrombosis
- Influenza Virus Research Studies
- Pregnancy and Medication Impact
- Eosinophilic Esophagitis
- Injury Epidemiology and Prevention
- Virology and Viral Diseases
- Infective Endocarditis Diagnosis and Management
- Poxvirus research and outbreaks
- Chronic Obstructive Pulmonary Disease (COPD) Research
GlaxoSmithKline (Spain)
2020-2024
Protection against vaccine-preventable diseases is especially relevant in older adults due to age-related decline immunity (immunosenescence). However, adult vaccination remains a challenge with overall low coverage rates, which has an impact on both the patients who have these and health care system terms of resource use costs derived. This study aimed estimate direct economic herpes zoster, pneumococcal disease, influenza pertussis Spanish 45 years older.Data from 2015 were extracted two...
To analyse the cost-effectiveness of MEP with standard care (SoC) versus other anti-IL-5 therapies approved for treatment severe eosinophilic asthma (SEA) patients, within Spanish National Health System (NHS) perspective.A Markov model a 4-week cycle length was used to compare BEN and RES as added SoC in management SEA, terms cost per QALY gained incremental ratio (ICER). Costs (€2019) were obtained from public sources, while utilities transition probabilities retrieved literature, e.g....
Immunization is the most effective strategy for prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroup B (MenB); however, parents need to weigh risk–benefit and financial impact immunizing their children against MenB in absence a national immunization program (NIP). This study aimed explore societal preferences (of pediatricians) regarding attributes vaccine Spain. A discrete choice experiment (DCE) based on cross-sectional surveys was carried out determine...
The recombinant zoster vaccine (RZV) is included in the Spanish National Immunisation Programme for adults 65 years of age (years), with a potential progressive catch-up program 66–80 years, starting 80 years. However, risk herpes (HZ) increases significantly from 50 We estimated public health impact (PHI) vaccinating ≥50 Spain versus no vaccination, using Markov model adapted to setting. simulated hypothetical cohort over lifetime, inputs publications, databases, or publications other...
Despite its impact on a patient's life, there is paucity of evidence the humanistic burden invasive meningococcal disease (IMD) due to serogroup B (MenB) in Spain. This study estimates total quality-adjusted life-year (QALY) loss MenB-IMD Spain from societal perspective.
Broad benefits of vaccination programs are well acknowledged but difficult to measure, especially when considering all vaccines included in a National Immunization Program (NIP). The aim was conduct cost-benefit analysis the entire NIP Spain, and an expanded including four potential additional programs. A performed Excel assess economic health (€) vaccinating single cohort newborns over lifetime horizon compared no vaccination, from societal perspective: firstly, according 2020 Spain...
Invasive meningococcal disease (IMD) is a severe infectious disease, mainly affecting children under 5 years, associated with long-term physical, neurological and psychological sequelae. In Spain, most IMD cases are caused by serogroup B (MenB). This study estimates its economic burden from societal perspective in Spain.A previously published bottom-up, model-based incidence costing approach Scholz et al. (2019) to estimate the of MenB Germany was adapted Spanish setting. Diagnosis...
<b>Objectives:</b> To describe the burden of eosinophilic COPD (blood eosinophil ≥150 cell/µL) and associated costs from Spanish societal perspective. <b>Methods:</b> Observational, longitudinal, retrospective, multicenter study in Pulmonology Services among patients (≥40 years) with diagnosis confirmed (post-bronchodilator FEV1/FVC<70%), history smoking ≥10 pack-year, receiving triple therapy (ICS/LAMA/LABA), exacerbations 12 months prior to inclusion visit (≥2 moderate or ≥1 severe)...
Background: Invasive meningococcal disease (IMD) remains a public health concern because of its serious consequences, which mainly affect infants and young children. In Spain, Neisseria meningitidis serotype B accounts for >40% IMD cases. The multicomponent serogroup vaccine (4CMenB) is available privately in the absence national funding Spain. This study evaluates whether potential inequities access to 4CMenB exist among families financial disparities. Methods: An ecological correlation...