A5013833954- Breast Cancer Treatment Studies
- Cancer Risks and Factors
- Cell Adhesion Molecules Research
- Global Cancer Incidence and Screening
- Breast Lesions and Carcinomas
- Chronic Lymphocytic Leukemia Research
- Multiple and Secondary Primary Cancers
- Lymphoma Diagnosis and Treatment
- CAR-T cell therapy research
- Urinary and Genital Oncology Studies
- Bladder and Urothelial Cancer Treatments
- Monoclonal and Polyclonal Antibodies Research
- Cutaneous lymphoproliferative disorders research
- CNS Lymphoma Diagnosis and Treatment
- Breast Implant and Reconstruction
- Lung Cancer Diagnosis and Treatment
- Cancer Diagnosis and Treatment
Rigshospitalet
2022-2025
Aarhus University Hospital
2013-2022
Background and purposeTo analyze the long-term risk of second primary solid non-breast cancer in a national population-based cohort 46,176 patients treated for early breast between 1982 2007.Patients methodsAll studied were according to guidelines Danish Breast Cancer Cooperative Group. The cancers was estimated by Standardised incidence ratios (SIRs) multivariate Cox regression models used estimate adjusted hazard (HR) among irradiated women compared non-irradiated. All on linear...
Between 1982 and 1990 the Danish Breast Cancer Cooperative Group (DBCG) conducted a randomized trial in high-risk pre- postmenopausal (<70 years) breast cancer patients comparing mastectomy plus adjuvant systemic therapy alone versus same treatment postoperative irradiation.To present comprehensive analysis of complete DBCG 82bc study with 30-year long-term follow-up therapeutic effect survival, together an additional focus on potential life-threatening morbidity related to cardiac...
Checkpoint inhibitors have changed the treatment landscape of advanced urothelial carcinoma (mUC), and recently, a fibroblast-growth-factor-receptor (FGFR) inhibitor has been introduced. This study aimed at estimating programmed death-ligand 1 (PD-L1) expression in primary tumors (PTs) PD-L1 concordance between PTs paired metastases 100 patients with UC managed real-world setting. Further, aim was to investigate FGFR1-3 aberrations correlation expression. immunohistochemistry performed on...
Clonal hematopoiesis is highly prevalent in elderly patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN), and around 20% of BPDCN have an associated myeloid malignancy. We present a patient localized concomitant myelodysplastic syndrome (MDS), previously followed for several years due to clonal cytopenia unknown significance. Compared targeted next‐generation sequencing (NGS) the skin tumor sequential bone marrow samples showed shared variants ASXL1 TET2 de novo NRAS variant...