A5083057834- Advanced biosensing and bioanalysis techniques
- Mass Spectrometry Techniques and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Biosensors and Analytical Detection
- Advanced Proteomics Techniques and Applications
- Radioactivity and Radon Measurements
- Astrophysics and Cosmic Phenomena
- Nanoparticles: synthesis and applications
- Venomous Animal Envenomation and Studies
- Advanced Nanomaterials in Catalysis
- Analytical chemistry methods development
- Ion channel regulation and function
- Radiation Detection and Scintillator Technologies
- Analytical Chemistry and Chromatography
- Neutrino Physics Research
- Nicotinic Acetylcholine Receptors Study
- Electrochemical Analysis and Applications
- Lipid Membrane Structure and Behavior
- Spaceflight effects on biology
- Quantum Dots Synthesis And Properties
- Mercury impact and mitigation studies
- Metabolomics and Mass Spectrometry Studies
- Earth Systems and Cosmic Evolution
- Nanoparticle-Based Drug Delivery
- Space Science and Extraterrestrial Life
Universidad de Oviedo
2017-2024
Canfranc Underground Laboratory
2022-2024
Herein, we introduce the first relative single-particle inductively coupled plasma mass spectrometry (spICP-MS) approach where size calibration is carried out using target NP itself measured under different instrumental conditions without external dependence on complex and prone-to-error determination of transport efficiency or flux calibrations, in contrast to most spICP-MS approaches. The simple proposed allows determining gold nanoparticle (AuNP) sizes, with errors ranging from 0.3 3.1%...
The Laboratorio Subterráneo de Canfranc (LSC) is the Spanish national hub for low radioactivity techniques and associated scientific technological applications. concentration of airborne radon a major component radioactive budget in neighborhood detectors. LSC hosts Radon Abatement System, which delivers suppressed air with 1.1±0.2 mBq/m3 222Rn. content continuously monitored an Electrostatic Monitor. Measurements double beta decay demonstrators NEXT-NEW CROSS gamma HPGe detectors show...
The synthesis and characterization of new engineered structured inorganic nanomaterials is essential in bioanalytical research requires for multidisciplinary analytical platforms.
One of the current challenges in medicine is to achieve a rapid and unequivocal detection quantification extremely low levels disease biomarkers complex biological samples. Here, we present development analytical evaluation low-cost smartphone-based system designed for ultrasensitive prostate-specific antigen (PSA) using two alternatives: electrochemical or optical, by coupling smartphone with portable potentiostat magnifying lenses. An antibody tagged gold nanoparticles (AuNPs), indium tin...
Inductively coupled plasma–mass spectrometry (ICP–MS) has been widely used in Life Sciences for the absolute quantification of biomolecules without specific standards, assuming same response generic compounds including complex biomolecules. However, contradictory results have published on this regard. We present first critical statistical comparison ICP–MS factors obtained 14 different relevant S-containing (three peptides, four proteins, one amino acid, two cofactors, three polyethylene...
A comparative study of the cytotoxicity HgSe nanoparticles and that induced by inorganic mercury methylmercury in two cell lines.
Elemental mass spectrometry is a powerful analytical technique widely established in inorganic analysis. However, despite its quantitative capabilities, it not yet fully integrated or considered Life Sciences fields like proteomics. Whereas true that ICP-MS has suffered from several instrumental and limitations have hindered applicability protein analysis, significant developments during the last decades turned into an interesting and, our opinion, tool to consider for accurate...
A major challenge in the development of bioanalytical methods is to achieve a rapid and robust quantification disease biomarkers present at very low concentration levels complex biological samples. An immunoassay platform presented herein for ultrasensitive fast detection prostate-specific antigen (PSA), well-recognized cancer biomarker. sandwich type immunosensor has been developed employing antibody labeled with inorganic nanoparticles acting as tags further indirect analyte. The required...
Deep underground laboratory infrastructures have extensively been used for exploring rare events, such as proton decay, dark matter searches or neutrino interactions, taking advantage of their large muon flux reduction. However, only very few investigations evaluated the effects low background radiation environments on living organisms. With this purpose, Canfranc Underground Laboratory (LSC) launched Biology Platform in 2021, which provides lab space approved biology experiments. Two...
The Laboratorio Subterra neo de Canfranc (LSC) is the national hub for low radioactivity techniques and associated scientific technological applications. concentration of airborne radon a major component radioactive budget in neighborhood detectors. LSC hosts Radon Abatement System (RAS), which delivers suppressed air with < 1 mBq/m3 222Rn. content continuously monitored an Electrostatic Monitor (ERM). Measurements doble beta decay demonstrators NEXT-NEW CROSS gamma HPGe detectors...