Liqiang Chen

ORCID: 0000-0001-5430-4585
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About
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Research Areas
  • Nanoparticles: synthesis and applications
  • Advanced biosensing and bioanalysis techniques
  • Environmental Toxicology and Ecotoxicology
  • Fish Ecology and Management Studies
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Microplastics and Plastic Pollution
  • Mercury impact and mitigation studies
  • Advanced Nanomaterials in Catalysis
  • Electrochemical sensors and biosensors
  • Fish Biology and Ecology Studies
  • Heavy metals in environment
  • Nanocluster Synthesis and Applications
  • Graphene and Nanomaterials Applications
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Conducting polymers and applications
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Corrosion Behavior and Inhibition
  • Polyoxometalates: Synthesis and Applications
  • biodegradable polymer synthesis and properties
  • Biosensors and Analytical Detection
  • Quantum Dots Synthesis And Properties
  • Prion Diseases and Protein Misfolding
  • Metal-Organic Frameworks: Synthesis and Applications
  • Hydrogen embrittlement and corrosion behaviors in metals
  • Hydrology and Sediment Transport Processes

Yunnan University
2016-2025

Fuyang Normal University
2023-2024

Shenyang Agricultural University
2022-2024

BOE Technology Group (China)
2021-2024

Yunnan Institute of Environmental Sciences
2017-2024

Powerchina Huadong Engineering Corporation (China)
2023-2024

PowerChina (China)
2023-2024

Guilin University of Technology
2023-2024

Zhejiang Wanli University
2023

China Meteorological Administration
2023

Silver nanoparticles (AgNPs) are increasingly being used as antimicrobial agents and drug carriers in biomedical fields. However, toxicological information on their effects red blood cells (RBCs) the mechanisms involved remain sparse. In this article, we examined size dependent nanotoxicity of AgNPs using three different characteristic sizes 15 nm (AgNPs15), 50 (AgNPs50), 100 (AgNPs100) against fish RBCs. Optical microscopy transmission electron observations showed that exhibited a effect...

10.1021/tx500479m article EN Chemical Research in Toxicology 2015-01-20

Although holding the advantages of both an aptamer and a molecular beacon (MB), (MAB) needs complicated expensive modifications at its ends usually has high background signal because low energy transfer efficiency between donor acceptor. To overcome these shortcomings, in this study, we develop long-range resonance (LrRET) system by separating from acceptor, wherein only one end MAB is fluorescently labeled acts as multiwalled carbon nanotubes (MWCNTs) are introduced test feasibility newly...

10.1021/ac100709s article EN Analytical Chemistry 2010-09-20

Aptamer-adapted silver nanoparticles (Apt-AgNPs) were developed as a novel optical probe for simultaneous intracellular protein imaging and single nanoparticle spectral analysis, wherein AgNPs act an illuminophore the aptamer biomolecule specific recognition unit, respectively. It was found that streptavidin-conjugated aptamer-functionalized show satisfactory biocompatibility stability in cell culture medium, thus not only can high contrast agent both dark-field light scattering microscope...

10.1021/jp9104618 article EN The Journal of Physical Chemistry B 2010-01-29

Abstract Freshwater fishes worldwide face an array of threats from dam construction, river fragmentation, pollution, over‐exploitation and interactions with introduced species. Such impacts are especially prevalent in densely populated countries undergoing rapid development, their effects felt most strongly where regional fish diversity is high. We reviewed studies the distribution freshwater species throughout China to map a biogeographical pattern ascertain environmental factors...

10.1111/faf.12011 article EN Fish and Fisheries 2013-01-10

The major challenge of prion disease diagnosis at the presymptomatic stage is how to sensitively or selectively discriminate and detect minute quantity disease-associated protein isoform (PrPRes) in complex biological systems such as serum brain homogenate. In this contribution, we developed a dual-aptamer strategy by taking advantages aptamers, excellent separation ability magnetic microparticles (MMPs), high fluorescence emission features quantum dots (QDs). Two aptamers (Apt1 Apt2), which...

10.1021/ac101865s article EN Analytical Chemistry 2010-11-01

Although nanoparticles have been widely used as optical contrasts for cell imaging, the complicated prefunctionalized steps and low labeling efficiency of nanoprobes greatly inhibit their applications in cellular protein imaging. In this study, we developed a novel general strategy that employs an aptamer not only recognizer recognition but also linker nanoreporter targeting to specifically label membrane proteins interest track endocytic pathway. With strategy, three kinds nanoparticles,...

10.1021/ac202810b article EN Analytical Chemistry 2012-02-27

Terrestrial microbial communities may take advantage of running waters and runoff to enter rivers mix with aquatic microorganisms. However, the environmental factors governing interchange community within a watercourse its surrounding environment composition resulting are often underestimated. The present study investigated effect flow rate on mixing water, soil, sediment biofilm at four sites along Lancang River one branch river in winter summer and, turn, resultant changes each habitat....

10.1093/femsec/fiaa132 article EN FEMS Microbiology Ecology 2020-06-28

Six new macrocyclic sesquiterpene pyridine alkaloids (SPAs) derivatives, named triptocumines A–F (1–6), as well eighteen known analogs, were isolated from Tripterygium hypoglaucum. The structures assigned based on analysis of spectroscopic data and electron circular dichroism (ECD) calculations. Furthermore, compounds 1-6, 8, 24 could effectively inhibit adenosine diphosphate-induced platelet aggregation, alleviate thrombosis oxidative stress in zebrafish, reduce endothelin-1 level, protect...

10.2139/ssrn.5065318 preprint EN 2025-01-01

Dam removal is becoming an effective approach for aquatic biodiversity restoration in damming river order to balance the ecosystem conservation with large-scale cascade damming. However, effects of dam on fish communities Asian mountainous rivers, which are dominated by Cypriniformes fishes, still not well known. To determine whether a benefit diversity, we investigated response assemblage using before- after-control-impact design two tributaries Lancang River (dam river: Jidu River, and...

10.1007/s11769-018-0995-x article EN Chinese Geographical Science 2018-09-05
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