A5077524418- Natural product bioactivities and synthesis
- Alkaloids: synthesis and pharmacology
- Phytochemistry and Bioactive Compounds
- Berberine and alkaloids research
- Phytochemistry and Biological Activities
- Botanical Research and Chemistry
- Oral microbiology and periodontitis research
- Phytochemical Studies and Bioactivities
- Bariatric Surgery and Outcomes
- Traditional and Medicinal Uses of Annonaceae
- Ziziphus Jujuba Studies and Applications
- Advanced Drug Delivery Systems
- Pharmacogenetics and Drug Metabolism
- Gallbladder and Bile Duct Disorders
- Bioactive natural compounds
- PARP inhibition in cancer therapy
- Underground infrastructure and sustainability
- Proteins in Food Systems
- Chemical Analysis and Environmental Impact
- Photodynamic Therapy Research Studies
- Advancements in Semiconductor Devices and Circuit Design
- Natural Compound Pharmacology Studies
- Carbohydrate Chemistry and Synthesis
- Body Contouring and Surgery
- Ovarian cancer diagnosis and treatment
Yunnan University of Traditional Chinese Medicine
2024-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Yunnan University
2018-2024
Yunnan Provincial Department of Education
2024
Kunming Institute of Botany
1990-2023
Chinese Academy of Sciences
2018-2023
University of Chinese Academy of Sciences
2015-2023
Beijing Obstetrics and Gynecology Hospital
2023
Capital Medical University
2023
Ningbo No. 2 Hospital
2020-2022
Clerodendranthus spicatus, popularly known as "kidney tea" in China, is consumed traditionally a functional food for treatment of renal inflammation, dysuria, and gout. We evaluated the effects C. spicatus on gout by assessing activities antihyperuricemia, anti-gouty arthritis, analgesia vivo, results indicated that ethyl acetate fraction shows potential activities. Subsequent phytochemical investigation this led to isolation 32 compounds, consisting 20 diterpenoids (including new...
Six new macrocyclic sesquiterpene pyridine alkaloids (SPAs) derivatives, named triptocumines A–F (1–6), as well eighteen known analogs, were isolated from Tripterygium hypoglaucum. The structures assigned based on analysis of spectroscopic data and electron circular dichroism (ECD) calculations. Furthermore, compounds 1-6, 8, 24 could effectively inhibit adenosine diphosphate-induced platelet aggregation, alleviate thrombosis oxidative stress in zebrafish, reduce endothelin-1 level, protect...
The fruits of Lycium barbarum have a long history as an edible and medicinal food in Asian regions multiple consumption methods; the polysaccharides (LBPs) are commonly considered their major immunological constituents. current study revealed that total phenolic amide moieties from L. showed greater potential immunomodulatory activity vivo than did LBPs. Through subsequent investigation on bioactive amides, three new lyciumamides L–N (1–3), well 12 analogues, were obtained fraction....
Summary The equilibrium solubility of sucrose in methyl stearate, oleate and laurate with or without the addition surfactants was investigated. side reactions, pyrolysis sucrose, glucose fructose, are also discussed through studying their data differential thermal analysis gravimetric analysis. Results show that solubilities esters fatty acids range from 0.01 g/100 g to 0.21 a surfactant‐free system temperature 40–140 °C. increased acid esters. Under strict anhydrous conditions, soap...
Purpose: To prepare and characterise ciprofloxacin mucoadhesive buccal films for localised, improved drug delivery in periodontitis.Methods: Ciprofloxacin-loaded containing 50 mg were prepared polymers sodium cellulose (SCMC) alginate, using a solvent evaporation method. The evaluated terms of thickness, weight, folding endurance, surface pH, content, swelling, properties, release characteristics, vivo anti-periodontitis activity, ampicillin as the standard.Results: showed good loading...
Objectives: Ovarian cancer is the most lethal gynecologic malignancy, and targeted therapy for different pathological types molecular phenotypes urgent to be studied. Studies have shown that MicroRNA-592 (miR-592) plays an important negative regulatory role in occurrence of gastrointestinal malignancies, breast cancer, non-small cell lung glioma, but expression miR-592 ovarian mechanism action are still unclear. Methods: The expressions were examined by RT-PCR Western Blot. Cell viability...
Abstract Hemoporfin is a novel second‐generation porphyrin‐related photosensitizer for ovarian cancer photodynamic treatment (PDT). The purpose of this study was to investigate the molecular mechanisms Hemoporfin‐mediated photocytotoxicity. Human epithelial cell line 3AO incubated with different concentrations Hemoporfin, and phototoxic effects on cells were determined using Cell Viability Analyzer. Apoptosis or necrosis by flow cytometry analysis Annexin V‐FITC apoptosis kit. Cellular...
Abstract Phytochemical investigation on the roots of Asparagus cochinchinensis led to isolation one new furostanol saponin, named 26- O - β d -glucopyranosyl-22 α -hydroxyl-(25 R )-Δ 5(6) -furost-3 ,26-diol-3- l -rhamnopyranosyl-(1 → 2)-[ -glucopyranosyl-(1 4)- 4)]- -glucopyranoside ( 1 ), along with three known congeners 2 ‒ 4 ). The structure saponin was elucidated via comprehensive inspection its HRMS and NMR spectral data as well chemical technology, whereas those ones were identified by...
Sixteen new quinolizidine alkaloids (QAs), named ormosianines A–P (1–16), and 18 known congeners (17–34) were isolated from the stems leaves of Ormosia yunnanensis. The structures elucidated based on spectroscopic analyses electron circular dichroism (ECD) calculations. Structurally, A (1) B (2) are first examples cytisine Ormosia-type with cleavage piperidine ring. Results acetylcholinesterase (AChE) inhibitory assay revealed that pentacycline QAs, including 1, 16, 24, 27–29, good AChE...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTwo New Pregnane Oligoglycosides from Dregea sinensis var. corrugataQ. D. Jin, Q. L. Zhou, and Z. MuCite this: J. Nat. Prod. 1989, 52, 6, 1214–1220Publication Date (Print):November 1, 1989Publication History Published online1 July 2004Published inissue 1 November 1989https://pubs.acs.org/doi/10.1021/np50066a003https://doi.org/10.1021/np50066a003research-articleACS PublicationsRequest reuse permissionsArticle Views94Altmetric-Citations10LEARN ABOUT...