A5100396445- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Alkaloids: synthesis and pharmacology
- Berberine and alkaloids research
- Natural product bioactivities and synthesis
- Traditional and Medicinal Uses of Annonaceae
- Phytochemistry and Biological Activities
- Pharmacological Effects of Natural Compounds
- Traditional Chinese Medicine Analysis
- Microbial Natural Products and Biosynthesis
- Supercapacitor Materials and Fabrication
- Biochemical and Molecular Research
- Fungal Biology and Applications
- Quantum Chromodynamics and Particle Interactions
- Particle physics theoretical and experimental studies
- Enzyme Structure and Function
- Plant-Microbe Interactions and Immunity
- Drug-Induced Hepatotoxicity and Protection
- Advancements in Battery Materials
- Catalytic Processes in Materials Science
- Plant Pathogens and Fungal Diseases
- Crystallography and molecular interactions
- Advanced Battery Materials and Technologies
- Phytochemical compounds biological activities
- Phytochemicals and Antioxidant Activities
Duquesne University
2018-2025
Wenzhou Medical University
2017-2025
Kunming Institute of Zoology
2022-2025
Zhejiang University
2023-2025
Lishui Central Hospital
2017-2025
Lishui University
2025
Chinese Academy of Sciences
2014-2025
Sun Yat-sen University
2023-2025
Yunnan University
2016-2025
Sun Yat-sen University Cancer Center
2024-2025
Recently emerged electronic skins with applications in on-body sensing and human–machine interfaces call for the development of high-performance skin-like electrodes. In this work, we report a highly robust, transparent, breathable epidermal electrode composed scaffold-reinforced conductive nanonetwork (SRCN). Solution-dispersed Ag nanowires, through facile vacuum filtration, are embedded into scaffold made polyamide nanofibers. Optical transmittance 84.9% at 550 nm wavelength is achieved...
Rheumatoid arthritis (RA) is one of the most common chronic autoimmune diseases. Despite considerable advances in clinical treatment RA, suboptimal response to therapy and discontinuation are still unresolved challenges due systemic toxicity. It crucial importance actively target deliver therapeutic agents inflamed joints order promote situ activity decrease In this study, we found that SPARC (secreted protein acidic rich cysteine) was overexpressed synovial fluid synovium RA patients as...
The polyketides are a diverse group of natural products with great significance as human and veterinary pharmaceuticals. A significant barrier to the production novel genetically engineered has been lack available heterologous expression systems for functional polyketide synthases (PKSs). Herein, we report an intact PKS in Escherichia coli Saccharomyces cerevisiae . fungal gene encoding 6-methylsalicylic acid synthase from Penicillium patulum was expressed E. S. (6-MSA) produced. In both...
The new melokhanines A–J (1–10) and 22 known (11–32) alkaloids were isolated from the twigs leaves of Melodinus khasianus. compounds their absolute configurations elucidated by extensive analysis spectroscopic, X-ray diffraction, computational data. Melokhanine A (1), composed a hydroxyindolinone linked to an octahydrofuro[2,3-b]pyridine moiety, is unprecedented monoterpenoid indole alkaloid. Melokhanines B–H (2–8) possess 6/5/5/6/6 pentacyclic alkaloid skeleton. Alkaloids 1–16, 25–27, 31,...
Abstract Metabolites from marine organisms have proven to be a rich source for the discovery of multiple potent bioactive molecules with diverse structures. In recent years, we initiated program investigate diversity secondary metabolites invertebrates and their symbiotic microorganisms collected South China Sea. this review, representative cases are summarized focusing on molecular diversity, mining, application natural products these organisms. To provide comprehensive introduction field...
Open AccessCCS ChemistryRESEARCH ARTICLES15 Mar 2024Imidazole-Linked Fully Conjugated Covalent Organic Framework for High-Performance Sodium-Ion Battery Lu Liu†, Yu Gong†, Yifan Tong, Hao Tian, Xubo Wang, Yiming Hu, Shaofeng Huang, Weiwei Sandeep Sharma, Jingnan Cui, Yinghua Jin, Weitao Gong and Wei Zhang Liu† State Key Laboratory of Fine Chemicals, School Chemical Engineering, Dalian University Technology, 116024 Department Chemistry, Colorado Boulder, 80309 , Gong† Tong Hebei Applied...
Abstract Inflammation in the testes induced by infection and autoimmunity contributes significantly to male infertility, a public health issue. Current therapies using antibiotics broad-spectrum anti-inflammatory drugs are ineffective against non-bacterial orchitis induce side effects. This highlights need explore pathogenesis of develop alternative therapeutic strategies. In this study, we demonstrated that Gasdermin D (GSDMD) was activated during uropathogenic Escherichia coli...
Elucidating the inherent origins of sluggish hydrogen evolution reaction (HER) kinetics in alkaline media and developing high-performance electrocatalysts are fundamental for advances conventional water electrolyzers emerging anion exchange membrane (AEM) electrolyzers. Here we present a facile electrochemical modification strategy synthesis bi-component Co–Mo(18%)/A-Co(OH)2 catalyst toward efficient HER catalysis media. Porous Co–Mo alloys with adjustable Mo/Co atomic ratio first prepared...
Efficient small interfering RNA (siRNA) delivery in the presence of serum is crucial importance for effective gene therapy. Fluorinated vectors are considered to be attractive candidates siRNA-mediated therapy because their efficacy serum-containing media. However, mechanisms driving superior transfection behavior fluorinated still not well-understood, and comprehensive investigations warranted. Herein, we fabricated a library perfluorooctanoyl fluoride-fluorinated (PFF-fluorinated)...
Article11 May 2020Open Access Source Data Blocking interaction between SHP2 and PD-1 denotes a novel opportunity for developing inhibitors Zhenzhen Fan MOE Key Laboratory of Tumor Molecular Biology Functional Protein Research Guangdong Higher Education Institutes, Institute Life Health Engineering, Jinan University, Guangzhou, China Search more papers by this author Yahui Tian Zhipeng Chen Lu Liu Qian Zhou Jingjing He Sun Yat-Sen University Cancer Center, James Coleman...