A5101958204- Bone Tissue Engineering Materials
- Traditional Chinese Medicine Analysis
- Hydrogels: synthesis, properties, applications
- Crystallization and Solubility Studies
- Influenza Virus Research Studies
- Polysaccharides Composition and Applications
- X-ray Diffraction in Crystallography
- Nanocomposite Films for Food Packaging
- Polysaccharides and Plant Cell Walls
- 3D Printing in Biomedical Research
- Toxin Mechanisms and Immunotoxins
- Tissue Engineering and Regenerative Medicine
- Simulation and Modeling Applications
- Telomeres, Telomerase, and Senescence
- Respiratory viral infections research
- Animal Virus Infections Studies
- Ginseng Biological Effects and Applications
- Electrospun Nanofibers in Biomedical Applications
- Immune Response and Inflammation
- Antioxidants, Aging, Portulaca oleracea
- Biological and pharmacological studies of plants
- Phytochemistry and Bioactive Compounds
- Medicinal Plants and Bioactive Compounds
- Wnt/β-catenin signaling in development and cancer
- Innovative Educational Techniques
Lanzhou University of Technology
2011-2021
State Key Laboratory of Complex Electromagnetic Environment Effects on Electronics and Information System
2016
National Engineering Research Center of Electromagnetic Radiation Control Materials
2016
People's Liberation Army No. 150 Hospital
2012
Gansu Agricultural University
2008-2009
Chinese Academy of Agricultural Sciences
2009
This study aimed to investigate the effects of polysaccharide from Angelica and Astragalus (AAP) on carbon tetrachloride (CCl 4 ) induced liver damage in mice. A total 120 Kunming mice were randomly distributed among 6 groups comprising (i) normal control mice, (ii) CCl treatment group, (iii) bifendate (iv) AAP (v) sinensis (ASP) (vi) membranaceus (AMP) group. AAP, ASP AMP administered treated with . The activities alanine transaminase (ALT) aspartate (AST) serum, superoxide dismutase (SOD)...
The application of pulsed electromagnetic fields (PEMFs) in the prevention and treatment osteoporosis has long been an area interest. However, clinical PEMFs remains limited because poor understanding PEMF action mechanism. Here, we report that promote bone formation by activating soluble adenylyl cyclase (sAC), cyclic adenosine monophosphate (cAMP), protein kinase A (PKA), cAMP response element-binding (CREB) signaling pathways. First, it was found 50 Hz 0.6 millitesla (mT) promoted...
High rate of platelet adhesion and limited biocompatibility were regarded as the chief weaknesses vascular tissue engineering scaffolds. The objective this research was to overcome these drawbacks by ultilizing coaxial electrospinning combine CDPS with PLA. PLA located at inner external layer respectively so that a "core-sheath" structure formed. properties scaffolds tested methods such mechanical testing, MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] assay subcutaneous...
Hypericum perforatum L., a plant used in Chinese herbal medicine, has been proven effective against many viral diseases. In the present study, therapeutic efficacy of an extract H. (HPE) influenza A virus (IAV) was investigated mice. Whether HPE would be promising agent for treatment evaluated by measuring protection rate, mean survival days, lung index, and titer, as well secretion IL-6, interleukin-10 (IL-10), tumour necrosis factor-α (TNF-α), interferon-gamma (IFN-γ) tissue serum on days...
Porous composite scaffold with Ligusticum wallichii polysaccharide and squid skin collagen was synthesized characterized. The showed good phosphate buffer solution (PBS) retention ability, slow biodegradation rate, high mechanical strength, superb cell proliferation promoting ability. PBS content value increased from 433.40% to 571.05%; the weight lost in seven days decreased 95.41% 34.35%; tensile strength of sample 0.19 0.81 MPa; seven-day relative growth rate (polysaccharide:collagen =...
The stiffness and gelation temperature of thermo-responsive chitosan (CS), glycerophosphate (GP) hydrogel is not enough for differentiation BMSCs injecting use in bone defect repair. To improve these weaknesses, a kind injectable (PMCG) was prepared with Chitosan (GP), polygonatum polysaccharide modified montmorillonite (PMMT). CS/GP (CG) 42 °C, the maximum mechanical strength 1061 Pa. amount PMMT increased, decreased to 28 increased 6789 At same time, addition PMMT, swelling property...
Abstract The purpose of this investigation was to develop the feasibility utilizing Angelica polysaccharide in vascular tissue engineering area. and poly lactic acid (PLA) microfibrous mixed different ratios were prepared with electrospinning apparatus. A series detection technology (SEC-LLS, SEM, MTT, paraffin sections, mechanical test) used characterize determine property composite scaffold such as molecular weight, biomechanical, bioactivity, cytotoxicity, biocompatibility,...
Angelica and Astragalus, Chinese herbal medicine, are used as immunostimulants for enriching the blood, anti-tumor antioxidation effects. However, synergistic mechanisms of antioxidant antitumor effects have long been object intensive study. We investigated deferring senile effect polysaccharides from Astragalus (AAP) on aging mice by determination contents monoamine oxidase (MAO) in brain, hydroxyproline (Hyp) skin. In addition, KM with murine H22 hepatocarcinoma cell model were to study...
Scaffolds made from single hydroxyapatite (HAp) possess neither biological properties of bone nor functions promoting vascularization and inhibiting immune rejection. To overcome these drawbacks HAp, Angelica sinensis polysaccharide (ASP)/HAp composite scaffolds were prepared its application possibility in tissue engineering was studied. The examined by mechanical test, releasing degradation histological evaluation. results showed that the had good ASP releasing. examination indicated...
Abstract To study the extraction technology of polysaccharides (AAP) from Chinese herbal medicine formula and its mechanism delaying aging. First, L9(3)4 orthogonal test was used to optimize optimal enzyme-assisted parameters polysaccharides. And anti-aging effects evaluated by detecting mitochondrial function, protein, DNA, adhesion molecules cell cycle in aging rats. The process were cellulase concentration 1.5%, pH at 5, enzyme temperature 50°C time 180 min. results showed that AAP can...
In order to improve the fidelity and controllable of electromagnetic environment(EME) building, build realistic EME for testing researching complex effect on electronic information systems, this paper puts forward Equivalent building methods based meta-elements. First, analysis domestic foreign research which presents current situation demand, then expounds core idea basing meta-elements realize equivalent building. Further it introduces extraction method signal environment meta-elements,...
Angelica and Astragalus, Chinese herbal medicine, are used as immunostimulants for enriching the blood, anti-tumor antioxidation effects. However, synergistic mechanisms of antioxidant effect have long been object intensive study. We investigated deferring senile AAP on aging mice by determination contents monoamine oxidase (MAO) in brain, hydroxyproline (Hyp) skin, hydrogen peroxide (H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O )...