Zhiwen Chen

ORCID: 0000-0002-0268-5942
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About
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Research Areas
  • Research in Cotton Cultivation
  • Plant Virus Research Studies
  • Plant Molecular Biology Research
  • Graphene and Nanomaterials Applications
  • Plant tissue culture and regeneration
  • Carbon and Quantum Dots Applications
  • Photosynthetic Processes and Mechanisms
  • Plant and Fungal Interactions Research
  • Plant Reproductive Biology
  • CRISPR and Genetic Engineering
  • Nanoparticles: synthesis and applications
  • Particle accelerators and beam dynamics
  • Magnetic confinement fusion research
  • Luminescence Properties of Advanced Materials
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Aquaculture Nutrition and Growth
  • Perovskite Materials and Applications
  • Multimodal Machine Learning Applications
  • Plant Physiology and Cultivation Studies
  • Medicinal Plants and Bioactive Compounds
  • Advancements in Battery Materials
  • Light effects on plants
  • Video Analysis and Summarization
  • Human Pose and Action Recognition

Shanxi Datong University
2020-2025

Hefei University of Technology
2025

University of Toronto
2025

Chinese Academy of Sciences
2011-2024

Shenzhen Institutes of Advanced Technology
2024

National Animal Husbandry Service
2024

South China Normal University
2024

Wuhan University
2023-2024

IRD Fuel Cells (Denmark)
2024

Jinan University
2024

Serine/arginine-rich splicing factor 3 (SRSF3) regulates mRNA alternative of more than 90% protein-coding genes, providing an essential source for biological versatility. This study finds that SRSF3 expression is associated with drug resistance and poor prognosis in pancreatic cancer. We also find ANRIL m6A modification cancer cells. More importantly, we demonstrate methylation on lncRNA the splicing. Moreover, our results show promotes gemcitabine by regulating ANRIL's ANRIL-208 (one...

10.1016/j.celrep.2022.110813 article EN cc-by-nc-nd Cell Reports 2022-05-01

Mitochondria are responsible for providing energy currency to life processes in the molecular form of ATP and therefore typically referred as power factories cells. Plant mitochondria also relevant common phenomenon cytoplasmic male sterility, which is agronomically important various crop species. Cytoplasmic sterility (CMS) a complex trait that may be influenced by patterns mitochondrial genome evolution, intergenomic gene transfer among organellar nuclear compartments plant Here, we review...

10.1080/07352689.2017.1327762 article EN cc-by-nc-nd Critical Reviews in Plant Sciences 2017-01-02

Pancreatic cancer (PC) is the fourth most common cause of cancer-related deaths in United States, suggesting that designing novel therapeutic strategy required to improve survival outcome patients diagnosed with PC. Recently, microRNAs (miRNA) have been found be involved regulation multiple aspects tumor development and progression including In this study, we investigate whether miR-34a plays a critical role control cell growth apoptosis PC cells. We Re-expression (forced expression)...

10.2174/138945012804545597 article EN Current Drug Targets 2012-12-18

Significance Plants recognize insect-derived molecules and make the accurate defense response during herbivory. However, insects release effectors that disturb host plant responses for fitness. Effectors are crucial components in biotic interactions. We identified a caterpillar-derived effector (HARP1) from oral secretion of cotton bollworm, devastating agricultural pest. HARP1 is released larvae to leaves feeding able migrate wounding site into cells automatically. interacts with...

10.1073/pnas.1905471116 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2019-06-20

Plant cell growth involves a complex interplay among cell-wall expansion, biosynthesis, and, in specific tissues, secondary wall (SCW) deposition, yet the coordination of these processes remains elusive. Cotton fiber cells are developmentally synchronous, highly elongated, and contain nearly pure cellulose when mature. Here, we report that transcription factor GhTCP4 plays an important role balancing cotton elongation synthesis. During development expression miR319 declines while transcript...

10.1016/j.molp.2020.05.006 article EN cc-by-nc-nd Molecular Plant 2020-05-16

Significance Cotton is an important crop, and terpenoids form the largest group of natural products. Gossypol related sesquiterpene aldehydes in cotton function as phytoalexins against pathogens pests but pose human health concerns, oil still widely used vegetable oil. We report isolation identification four enzymes recharacterization one previously reported P450. are now close to completion gossypol pathway, progress agricultural plant sciences, data beneficial improving food safety. Among...

10.1073/pnas.1805085115 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2018-05-21

Abstract Silicon‐carbon composites (Si/C) with multistage structures enable structural integrity during cycling. However, the lack of controllable structure preparation on a large scale hinders stability improvement in practical applications. Herein, new strategy is proposed to synthesize kilogram‐scale Si/C (PySi/C) featuring dual‐model carbon one step. The combination an onion‐like coating Si surface independent pyrolytic accomplished through precise adjustment pyrolysis temperature....

10.1002/adfm.202423700 article EN Advanced Functional Materials 2025-01-12

Curcumin has been reported to inhibit cell growth and induce apoptosis in oral cancer cells. Although many studies have done uncover the mechanisms by which curcumin exerts its antitumor activity, precise molecular remain be unclear. In present study, we assessed effects of on viability cancer. For mechanistic studies, used multiple cellular approaches such as gene transfection, real-time RT-PCR, Western blotting, invasion assay, ELISA. first time, found a significant reduction...

10.1002/jcb.23019 article EN Journal of Cellular Biochemistry 2011-01-18

Cotton cultivars have evolved to produce extensive, long, seed-born fibers important for the textile industry, but we know little about molecular mechanism underlying spinnable fiber formation. Here, report how PACLOBUTRAZOL RESISTANCE 1 (PRE1) in cotton, which encodes a basic helix-loop-helix (bHLH) transcription factor, is target gene of evolution. Differential expression homoeologous genes polyploids thought be plant adaptation and novel phenotypes. PRE1 specific cotton cells, upregulated...

10.1111/nph.15063 article EN cc-by New Phytologist 2018-02-21

Metastasis, in which cancer cells detach from the original site and colonise other organs, is primary cause of death induced by bladder (BCa). Epithelial Membrane Protein 1 (EMP1) dysregulated many human cancers, its clinical significance biological function diseases, including BCa, are largely unclear. Here, we demonstrated that EMP1 was downregulated BCa cells. The deficiency promotes migration confers resistance to ferroptosis/oxidative stress cells, favouring tumour cell metastasis....

10.1016/j.freeradbiomed.2022.06.247 article EN cc-by-nc-nd Free Radical Biology and Medicine 2022-07-16

Abstract The recently discovered human enzyme DNA polymerase ι (pol ι) has been shown to have an exceptionally high error rate on artificial templates. Although there is a considerable body of in vitro evidence for role pol lesion bypass, no vivo confirm this action. We report here that expression elevated breast cancer cells and correlates with significant decrease replication fidelity. also demonstrate UV treatment additionally increases peak occurring between 30 min 2 h after cellular...

10.1158/0008-5472.can-04-0603 article EN Cancer Research 2004-08-15

The mitochondrial genome from upland cotton, G. hirsutum, was previously sequenced. To elucidate the evolution of genomic diversity within a single genus, we sequenced Sea Island cotton (Gossypium barbadense L.). Mitochondrial DNA week-old etiolated seedlings extracted isolated organelles using discontinuous sucrose density gradient method. with Solexa paired-end, 90 bp read. clean reads were assembled into contigs ABySS and finished via additional fosmid BAC sequencing. Finally, annotated...

10.1186/s12864-015-1988-0 article EN cc-by BMC Genomics 2015-10-12

The cotton genus (Gossypium spp.) contains 8 monophyletic diploid genome groups (A, B, C, D, E, F, G, K) and a single allotetraploid clade (AD). To gain insight into the phylogeny of Gossypium molecular evolution chloroplast in this group, we performed comparative analysis 19 genomes, six reported here for first time. Nucleotide distance non-coding regions was about three times that coding regions. As expected, distances were smaller within than among groups. Phylogenetic topologies based on...

10.1371/journal.pone.0157183 article EN cc-by PLoS ONE 2016-06-16

Graphene reportedly exerts positive effects on plant root growth and development, although the corresponding molecular response mechanism remains to be elucidated. Maize seeds were randomly divided into a control experimental group, roots of Zea mays L. seedlings watered with different concentrations (0–100 mg/L) graphene explore development Z . Upon evaluating indices, 50 mg/L remarkably increased total length, volume, number tips forks maize compared those group. We observed that contents...

10.1371/journal.pone.0244856 article EN cc-by PLoS ONE 2021-01-04

Abstract Background Cotton fiber is a model system for studying plant cell development. At present, the functions of many transcription factors in cotton development have been elucidated, however, roles auxin response factor (ARF) genes need be further explored. Results Here, we identify three species: tetraploid upland G. hirsutum , which has 73 ARF genes, and its putative extent parental diploids arboreum raimondii 36 35 ARFs, respectively. Ka Ks analyses revealed that undergone asymmetric...

10.1186/s12864-021-07504-6 article EN cc-by BMC Genomics 2021-03-22

Salt stress is an environmental factor that limits plant seed germination, growth, and survival. We performed a comparative RNA sequencing transcriptome analysis during germination of the seeds from two cultivars with contrasting salt tolerance responses. A transcriptomic comparison between salt-tolerant cotton cv Jin-mian 25 salt-sensitive Su-mian 3 revealed both similar differential expression patterns genotypes stress. The genes related to aquaporins, kinases, reactive oxygen species...

10.3390/ijms26010329 article EN International Journal of Molecular Sciences 2025-01-02

This experiment aimed to study the effects of methionine (Met) on growth performance, intestinal structure and transport, Met metabolism TOR signaling pathway in golden pompano (Trachinotus ovatus). Fish (9.12 ±0.03 g) were fed with six diets added 0.10%, 0.20%, 0.30%, 0.40% 0.50% DL-Met for 8 weeks. Our showed that supplementation significantly increased fish growth, villus length, crypt depth mRNA levels amino acid transporters including asc-1, asct2, cat1 (P < 0.05). Liver histological...

10.2139/ssrn.5074228 preprint EN 2025-01-01

Luminescence thermometry (LT) has emerged as a valuable technique for noncontact temperature sensing, with applications in real-time monitoring, microelectronics thermal management, and health surveillance. In this work, we developed temperature-sensitive material, potassium chloride(KCl):Sb3+, investigated its luminescent properties. The results indicated that the material exhibited broad excitation spectra within 250–400 nm wavelength range maximum at 366 showed band emission 590 upon...

10.1021/acsaom.4c00530 article EN ACS Applied Optical Materials 2025-02-17
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