Xiaoyan Cai

ORCID: 0000-0002-8351-4837
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Research Areas
  • Research in Cotton Cultivation
  • Plant Virus Research Studies
  • Plant Molecular Biology Research
  • Plant Stress Responses and Tolerance
  • Plant and Fungal Interactions Research
  • Photosynthetic Processes and Mechanisms
  • Plant tissue culture and regeneration
  • Plant Gene Expression Analysis
  • Plant nutrient uptake and metabolism
  • Chromosomal and Genetic Variations
  • Plant Reproductive Biology
  • Cancer-related molecular mechanisms research
  • Genetic Mapping and Diversity in Plants and Animals
  • Animal Genetics and Reproduction
  • Rice Cultivation and Yield Improvement
  • Genetic diversity and population structure
  • Plant and animal studies
  • MicroRNA in disease regulation
  • Plant-Microbe Interactions and Immunity
  • Cancer Research and Treatments
  • Plant Water Relations and Carbon Dynamics
  • Bacteriophages and microbial interactions
  • Cancer, Hypoxia, and Metabolism
  • Plant biochemistry and biosynthesis
  • Blood Pressure and Hypertension Studies

Air Force Medical University
2025

Cotton Research Institute
2015-2024

Chinese Academy of Agricultural Sciences
2015-2024

Ningxia University
2020-2024

Sanya University
2023-2024

Zhangzhou Municipal Hospital of Fujian Province
2023

Fujian Medical University
2023

University of California, Davis
2022

Zhengzhou University
2019-2022

McGill University
2022

Late embryogenesis abundant (LEA) proteins are large groups of hydrophilic with major role in drought and other abiotic stresses tolerance plants. In-depth study characterization LEA protein families have been carried out plants, but not upland cotton. The main aim this research work was to characterize the late carry gene expression analysis determine their potential stress Increased cotton production face declining precipitation availability fresh water for agriculture use is focus...

10.1186/s12863-017-0596-1 article EN cc-by BMC Genomic Data 2018-01-15

Cotton is a pioneer of saline land crop, while salt stress still causes its growth inhibition and fiber production decrease. Phenotype identification showed better tolerance wild diploid cotton species Gossypium klotzschianum. To elucidate the salt-tolerant mechanisms in G. klotzschianum, we firstly detected changes hormones, H2O2 glutathione (GSSH GSH), then investigated gene expression pattern roots leaves treated with 300 mM NaCl for 0, 3, 12, 48 h, each time control by RNA-seq on...

10.1371/journal.pone.0178313 article EN cc-by PLoS ONE 2017-05-26

Abiotic stresses have negative effects on plants growth and development. Plants, being sessile, developed specific adaptive strategies that allow them to rapidly detect respond abiotic stress factors. The detoxification efflux carriers (DTX)/multidrug toxic compound extrusion (MATE) transporters are of significance in the translocation abscisic acid (ABA), a phytohormone with profound role under various conditions. ABA signaling cascades core regulators responses plants, triggering major...

10.3389/fpls.2019.00299 article EN cc-by Frontiers in Plant Science 2019-03-12

Allotetraploid cotton (Gossypium) species represents a model system for the study of plant polyploidy, molecular evolution, and domestication. Here, chromosome-scale genome sequences were obtained assembled two recently described wild tetraploid cotton, Gossypium ekmanianum [(AD)6, Ge] stephensii [(AD)7, Gs], one early form domesticated hirsutum, race punctatum [(AD)1, Ghp]. Based on phylogenomic analysis, we provide dated whole-genome level perspective evolution clade resolved evolutionary...

10.1073/pnas.2208496119 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2022-09-19

The diploid wild cotton species Gossypium australe possesses excellent traits including resistance to disease and delayed gland morphogenesis, has been successfully used for distant breeding programmes incorporate into domesticated cotton. Here, we sequenced the G. genome by integrating PacBio, Illumina short read, BioNano (DLS) Hi-C technologies, acquired a high-quality reference with contig N50 of 1.83 Mb scaffold 143.60 Mb. We found that 73.5% is composed various repeat sequences,...

10.1111/pbi.13249 article EN cc-by Plant Biotechnology Journal 2019-09-03

Cotton (Gossypium spp.) is the number one crop cultivated for fiber production and cornerstone of textile industry. Drought salt stress are major abiotic stresses, which can have a huge economic impact on cotton production; this has been aggravated with continued climate change, compounded by pollution. Various survival strategies evolved plants include induction various responsive genes, such as cyclin dependent kinases (CDKs). In study, we performed whole-genome identification analysis CDK...

10.3390/ijms19092625 article EN International Journal of Molecular Sciences 2018-09-05

Auxins play an important role in plant growth and development; the auxins responsive gene; auxin/indole-3-acetic acid (Aux/IAA), small auxin-up RNAs (SAUR) Gretchen Hagen3 (GH3) control their mechanisms. The GH3 genes function homeostasis by catalytic activities auxin conjugation bounding free indole-3-acetic (IAA) to amino acids.In our study, we identified three cotton species; Gossypium hirsutum, arboreum raimondii, analyzed chromosomal distribution, phylogenetic relationships,...

10.1186/s12863-019-0756-6 article EN cc-by BMC Genomic Data 2019-07-23

Increasing soil salinization has led to severe losses of plant yield and quality. Thus, it is urgent investigate the molecular mechanism salt stress response. In this study, we took systematically analyzed cotton root response by single-cell transcriptomics technology; 56,281 high-quality cells were totally obtained from 5-days-old lateral tips Gossypium arboreum under natural growth different salt-treatment conditions. Ten cell types with an array novel marker genes synthetically identified...

10.1016/j.xplc.2023.100740 article EN cc-by-nc-nd Plant Communications 2023-10-29

Abstract The extrusion of toxins and substances at a cellular level is vital life process in plants under abiotic stress. multidrug toxic compound (MATE) gene family plays large role the exportation other substrates. We carried out genome-wide analysis MATE families Gossypium raimondii arboreum assessed their expression levels salt, cadmium drought stresses. identified 70 68 genes G. arboreum, respectively. majority were predicted to be localized within plasma membrane, with some distributed...

10.1534/g3.118.200232 article EN cc-by G3 Genes Genomes Genetics 2018-05-24

Abstract Late embryogenesis abundant (LEA) proteins play key roles in plant drought tolerance. In this study, 157, 85 and 89 candidate LEA2 were identified G. hirsutum, arboreum raimondii respectively. genes classified into 6 groups, designated as group 1 to 6. Phylogenetic tree analysis revealed orthologous gene pairs within the cotton genome. The specific motifs E, R D addition Y, K S motifs. distributed on all chromosomes. LEA2s found be highly enriched non-polar, aliphatic amino acid...

10.1534/g3.118.200423 article EN cc-by G3 Genes Genomes Genetics 2018-06-22

Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1), also known as cluster of differentiation (CD)39, is the rate-limiting enzyme in generation immunosuppressive adenosine and important tumor progression. The present study evaluated expression CD39+ forkhead box P3 (FoxP3)+ regulatory T (Treg) cells gastric cancer (GC), determined their prognostic roles patients with GC following radical resection. It was observed that CD39 expressed at significantly higher rates tissues compared...

10.3892/ol.2016.5189 article EN Oncology Letters 2016-09-26

We identified 102, 51 and proteins encoded by the trihelix genes in Gossypium hirsutum, arboreum raimondii, respectively. RNA sequence data real-time quantitative polymerase chain reaction analysis showed that Gh_A05G2067 (GT-2) was highly upregulated under drought salt stress conditions. Transient expression of GT-2-green fluorescent protein fusion protoplast GT-2 localized nucleus. The overexpression conferred an enhanced tolerance to cotton, with lower malondialdehyde, hydrogen peroxide...

10.1111/ppl.12920 article EN cc-by Physiologia Plantarum 2019-01-10

Verticillium wilt that is caused by dahliae, does result in massive annual yield losses and fiber quality decline cotton. Control conventional mechanisms not possible due to a wide host range the longevity of dormant fungi soil case absence suitable host. Plants have developed various boost their immunity against diseases, one through induction genes. In this research, we carried out RNA sequencing then identified members adenosine triphosphate (ATP)-binding cassette (ABC) proteins be...

10.3390/genes10020110 article EN Genes 2019-02-01

The cotton genus (Gossypium spp.) contains 8 monophyletic diploid genome groups (A, B, C, D, E, F, G, K) and a single allotetraploid clade (AD). To gain insight into the phylogeny of Gossypium molecular evolution chloroplast in this group, we performed comparative analysis 19 genomes, six reported here for first time. Nucleotide distance non-coding regions was about three times that coding regions. As expected, distances were smaller within than among groups. Phylogenetic topologies based on...

10.1371/journal.pone.0157183 article EN cc-by PLoS ONE 2016-06-16

We identified 672, 374, and 379 CYPs proteins encoded by the genes in Gossypiumhirsutum, Gossypiumraimondii, Gossypiumarboreum, respectively. The were found to be distributed all 26 chromosomes of tetraploid cotton, with chrA05, chrA12, their homeolog harboring highest number genes. physiochemical properties CYP450 varied terms protein lengths, molecular weight, isoelectric points (pI), even grand hydropathy values (GRAVY). However, over 99% cotton had GRAVY below 0, which indicated that...

10.3390/genes10030226 article EN Genes 2019-03-18

Cotton production is on the decline due to ever-changing environmental conditions. Drought and salinity stress contribute over 30% of total loss in cotton production, situation has worsened more narrow genetic base cultivated upland cotton. The diversity been eroded years intense selection inbreeding. To break bottleneck, wild progenitors offer unique traits which can be introgressed into cotton, thereby improving their performance. In this research, we developed a BC₂F₂ population between...

10.3390/ijms19061614 article EN International Journal of Molecular Sciences 2018-05-30

Reactive oxygen species (ROS) are important molecules in the plant, which involved many biological processes, including fiber development and adaptation to abiotic stress cotton. We carried out transcription analysis determine evolution of ROS genes analyzed their expression levels various tissues cotton plant under conditions. There were 515, 260, 261 network that identified

10.3390/ijms20081863 article EN International Journal of Molecular Sciences 2019-04-15

Cotton grows in altering environments that are often unfavorable or stressful for its growth and development. Consequently, the plant must cope with abiotic stresses such as soil salinity, drought, excessive temperatures. Alkali-salt stress response remains a cumbersome biological process is regulated via multifaceted transcriptional regulatory network cotton.To discover molecular mechanisms of alkali-salt cotton, comprehensive transcriptome analysis was carried out after treatment three...

10.1186/s12864-019-6375-9 article EN cc-by BMC Genomics 2020-01-06

As one of the pioneer crops widely planted in saline-alkaline areas, Gossypium provides daily necessities, including natural fiber, vegetable proteins, and edible oils. However, cotton fiber yield quality are highly influenced by salt stress. Therefore, elucidating molecular mechanisms response to salinity stress is importance breed new cultivars with high tolerance. In this study, we first developed a method for single-cell RNA-seq based on isolating protoplast from root tips; then, studied...

10.3390/ijms23052845 article EN International Journal of Molecular Sciences 2022-03-05

To explore the distribution characteristics of glioma-associated oncogene homolog 1 (Gli1) positive cells during orthodontic tooth movement process and conduct a proteomic analysis these cells.

10.3760/cma.j.cn112144-20240509-00192 article EN PubMed 2025-01-02
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