A5032586512- Retinal Diseases and Treatments
- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Retinal Imaging and Analysis
- Aquaculture Nutrition and Growth
- Genomics and Rare Diseases
- Optical Coherence Tomography Applications
- Retinal Development and Disorders
- Genetics and Neurodevelopmental Disorders
- Global Cancer Incidence and Screening
- Retinal and Optic Conditions
- Aquaculture disease management and microbiota
- Biological and pharmacological studies of plants
- Epilepsy research and treatment
- Gut microbiota and health
- EEG and Brain-Computer Interfaces
- Retinopathy of Prematurity Studies
- Genomic variations and chromosomal abnormalities
- Ginseng Biological Effects and Applications
- Functional Brain Connectivity Studies
- Medicinal Plants and Neuroprotection
- Clostridium difficile and Clostridium perfringens research
- Fungal Biology and Applications
- Cerebral Palsy and Movement Disorders
Affiliated Eye Hospital of Wenzhou Medical College
2020-2025
Wenzhou Medical University
2015-2025
National Clinical Research
2022-2025
Nanchang University
2025
South China Normal University
2021-2024
PLA Academy of Military Science
2022-2024
Peking University Shenzhen Hospital
2022-2024
Chinese PLA General Hospital
2022-2024
Chinese People’s Liberation Army 263 hospital
2021-2024
Shanghai University
2024
Myopia is the most common cause of visual impairment worldwide,1Holden B.A. Fricke T.R. Wilson D.A. et al.Global prevalence myopia and high temporal trends from 2000 through 2050.Ophthalmology. 2016; 123: 1036-1042Abstract Full Text PDF PubMed Scopus (2814) Google Scholar younger age at onset may progress to myopia.2Gwiazda J. Hyman L. Dong L.M. al.Factors associated with after 7 years follow-up in Correction Evaluation Trial (COMET) cohort.Ophthalmic Epidemiol. 2007; 14: 230-237Crossref...
Abstract Purpose To evaluate the 1‐year myopia control efficacy of a spectacle lens with annular cylindrical microstructures. Methods A total 118 consecutive eligible children aged 8–12 years −1.00 D to −4.00 spherical component and <1.50 astigmatism were enrolled between August 2020 November at Eye Hospital Wenzhou Medical University. Participants randomly assigned wear refractive element (CARE) ( n = 61) or single‐vision 57) lenses. Cycloplegic autorefraction (spherical equivalent...
This study aimed to investigate the application of cottonseed protein concentrate (CPC) in Chinese mitten crabs (Eriocheir sinensis). First, apparent digestibility coefficient (ADC) CPC, fish meal and soybean were compared (21.72 ± 0.33 g). The ADC CPC was 90.42%, which significantly higher than that (83.16%) (P < 0.05). Phe, Cys Glu those meal, while Ile, Leu, Lys, Met, Thr Ala lower Second, we investigated effects substitution by on growth performance, free amino acid profile, expression...
Abstract Background Myopia is the most common visual impairment in children and adolescents worldwide. This study described an economical effective population-based screening pipeline performed project of a million scale myopia survey (CAMS), which will shed light on further from level epidemiology precision medicine. Methods We developed novel pattern, intelligent process internet-based information transmission analysis system to carry out consisting school Wenzhou, China. The examination...
Purpose To evaluate the repeatability, reproducibility, and agreement of thickness profile measurements eight intra-retinal layers determined by an automated algorithm applied to optical coherence tomography (OCT) images from two different instruments. Methods Twenty normal subjects (12 males, 8 females; 24 32 years old) were enrolled. Imaging was performed with a custom built ultra-high resolution OCT instrument (UHR-OCT, ∼3 µm resolution) commercial RTVue100 (∼5 instrument. An developed...
This experiment aimed to study the effects of methionine (Met) on growth performance, intestinal structure and transport, Met metabolism TOR signaling pathway in golden pompano (Trachinotus ovatus). Fish (9.12 ±0.03 g) were fed with six diets added 0.10%, 0.20%, 0.30%, 0.40% 0.50% DL-Met for 8 weeks. Our showed that supplementation significantly increased fish growth, villus length, crypt depth mRNA levels amino acid transporters including asc-1, asct2, cat1 (P < 0.05). Liver histological...
High myopia (HM) is a severe form of refractive error that results in irreversible visual impairment and even blindness. However, the genetic pathological mechanisms underlying this condition are not yet fully understood. From adolescents survey cohort 1015 HM patients, pathogenic missense mutations were identified ZC3H11A gene four patients by whole exome sequencing. This zinc finger stress-induced protein plays significant role regulating nuclear mRNA export. To better understand function...
Abstract Background This study aims to examine interocular differences in the choroidal thickness and vascular density of choriocapillaris anisometropic myopes further explore relationship between blood flow myopia. Methods The sample comprised 44 participants with myopia, aged 9 18 years, normal best-corrected visual acuity. All underwent a series examinations, including spherical equivalent refraction (SER) axial length (AL), measured by Lenstar optical biometer coherence tomography...
Genetic skeletal disorders (GSD) involving the system arises through disturbances in complex processes of development, growth and homeostasis remain a diagnostic challenge because their clinical heterogeneity genetic variety. Over past decades, tremendous effort platforms have been made to explore heterogeneity, massive new genes mutations identified different GSD, but information supplied by literature is still limited it hard meet further needs scientists clinicians. In this study,...
To evaluate the contrast sensitivity function (CSF), chorioretinal thickness and vascular density as well their relationships in subjects with simple early-stage high myopia.Eighty-one young were enrolled this study. They categorized into myopia group (sHM, n = 51) low-moderate (control group, 30). Monocular CSF under best correction was measured qCSF method. Retinal superficial deep density, inner outer retinal choroidal using optical coherence tomography angiography.The area log (AULCSF)...
Neuromyelitis optica spectrum disorder (NMOSD), a severe demyelinating disease, is rare among children. Plasma exchange (PE) widely used as salvage therapy for and corticosteroid-unresponsive patients with NMOSD. Presently, there are limited studies on the safety efficacy of PE in children Herein, we report case six NMOSD who received along outcomes adverse events. All (female, age at onset 4 years 9 months–13 2 months) were AQP4-IgG positive standard using COM.TEC Cell Separator. The...
Purpose To investigate the contrast sensitivity function (CSF) changes in simple high myopia (SHM) and evaluate correlations between these with early retinal microstructure. Methods This prospective study comprised 81 subjects, 20 emmetropia (EM), 26 low moderate (LM/MM), 35 SHM. The area under log CSF curve (AULCSF) cut-off spatial frequency (Cut-off SF) were employed as measures of CSF. Adaptive optics (AO) was to quantify cone density, spacing, regularity. thickness blood flow sublayers...
The structural characteristics of the outer retinal layers in primary open angle glaucoma (POAG) are still controversial, and these changes, along with those inner layers, could have clinical and/or pathophysiological significance. A custom-built ultra-high resolution optical coherence tomography (UHR-OCT) combined an automated segmentation algorithm can image measure eight intra-retinal layers. purpose this study is to determine thickness macular especially POAG patients. Thirty-four...