A5031736354- Health disparities and outcomes
- Global Health Care Issues
- Air Quality and Health Impacts
- Birth, Development, and Health
- Healthcare Systems and Reforms
- Climate Change and Health Impacts
- Chronic Disease Management Strategies
- Health, Environment, Cognitive Aging
- COVID-19 epidemiological studies
- Vaccine Coverage and Hesitancy
- Insurance, Mortality, Demography, Risk Management
- Suicide and Self-Harm Studies
- Gastric Cancer Management and Outcomes
- Respiratory viral infections research
- Zoonotic diseases and public health
- COVID-19 and Mental Health
- Intergenerational Family Dynamics and Caregiving
- Inflammatory mediators and NSAID effects
- Air Quality Monitoring and Forecasting
- Long-Term Effects of COVID-19
- Frailty in Older Adults
- Viral Infections and Outbreaks Research
- Cardiovascular Health and Risk Factors
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pharmacological Effects of Natural Compounds
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2025
Chinese PLA General Hospital
2010-2024
National Clinical Research Center for Digestive Diseases
2024
Peking Union Medical College Hospital
2023-2024
Affiliated Eye Hospital of Wenzhou Medical College
2024
Wenzhou Medical University
2024
Chinese Academy of International Trade and Economic Cooperation
2023-2024
Peking University
2018-2024
Academy of Medical Sciences
2023
People's Liberation Army No. 150 Hospital
2012
<sec> <b>What is already known about this topic?</b> As the largest country in world, China experienced a demographic transition at historic scale during past 50 years with extraordinarily associated changes age structure of population, declining fertility rates, accelerating process population aging, and growing scale. </sec><sec> added by report?</b> This study presented future trends five important indicators China. From 2015–2050, outstanding — increases life expectancy declines rate...
Abstract Despite evidence indicating increased risk of psychiatric issues among COVID-19 survivors, questions persist about long-term mental health outcomes and the protective effect vaccination. Using UK Biobank data, three cohorts were constructed: SARS-CoV-2 infection ( n = 26,101), contemporary control with no 380,337) historical predating pandemic 390,621). Compared controls, infected participants had higher subsequent risks incident at 1 year (hazard ratio (HR): 1.54, 95% CI 1.42–1.67;...
Early-life tobacco exposure serves as a non-negligible risk factor for aging-related diseases. To understand the underlying mechanisms, we explored associations of early-life with accelerated biological aging and further assessed joint effects genetic susceptibility. Compared those without in utero exposure, participants had an increase Klemera-Doubal age (KDM-BA) PhenoAge acceleration 0.26 0.49 years, respectively, but decrease telomere length 5.34% among 276,259 participants. We also found...
The objective was to evaluate the longitudinal patterns of central and general obesity, identify their genetic behavioral risk determinants, investigate association distinct obesity trajectories beyond middle age with subsequent cognitive decline developing dementia in late life. Using a nationally representative, longitudinal, community-based cohort, we examined trajectory over 14-year span employing latent mixture modeling. We then evaluated relationship through linear mixed models using...
To determine whether serum levels of carcinoembryonic antigen (CEA) correlate with the presence primary colorectal cancer (CRC), and/or recurrent CRC following radical resection.A total 413 patients underwent surgery between January 1998 and December 2002 in our department were enrolled this study. The median follow-up period was 69 mo (range, 3-118 mo), recurrence experienced by 90/413 (21.8%) patients. Serum CEA assayed preoperatively, using a cutoff value 5 ng/mL, divided into two groups,...
This study aimed to examine urban-rural disparities in the prevalence and trends of depressive symptoms (DS) among Chinese elderly associated factors.A total 8025, 7808, 4887 respondents aged 60 years above were selected from China Family Panel Studies (CFPS) 2016, 2018, 2020, respectively. DS was assessed using a short version Center for Epidemiologic Depression Scale (CES-D). Twenty-two factors six categories included random forest (RF) models. All comparisons conducted based on good model...
Population aging is an irreversible process in the development of modern society, which brings challenges to comprehensive modernized social governance. a "dualistic" issue that not only leads labor force structure but also creates new demographic dividends. This study describes core thoughts developmental gerontology (DG), provides insight into relationship between active and governance for society. The DG will provide feasible sustainable path integrate coordinate population aging, economy.
Abstract Effective prevention strategies for post-COVID complications are crucial patients, clinicians, and policy makers to mitigate their cumulative burden. This study evaluated the association of modifiable lifestyle factors (smoking, alcohol intake, BMI, physical activity, sedentary time, sleep duration, dietary habits) with COVID-19 multisystem sequelae, death, hospitalization in UK Biobank cohort ( n = 68,896). A favorable (6-10 healthy factors; 46.4%) was associated a 36% lower risk...
Purpose Diabetes mellitus is emerging as an epidemic worldwide, and the incidence prevalence of diabetes have drastically changed in China over past 30 years, but data on its mortality rate are scarce. This study aimed to analyze time trends rates among patients with rural urban population between 1987 2019. Methods The research come from China’s annual report national health statistics Chinese Health Statistics Yearbook. Age-standardized were calculated by using direct method based World...
Objectives China has implemented an equalization of public health Services policy for migrants in 40 pilot cities since 2013. The main objective this study is to explore the effect migrant-based reform on status migrant population China. Methods Using Migrants Dynamic Survey (CMDS), we included 152,000 aged 15 years or over 2018. Standardized questionnaires were used collect socio-economic information and self-reported status. Associations between services estimated using Multiple regression...
Cardiometabolic multimorbidity (CMM) refers to the presence of multiple cardiovascular and metabolic diseases (CMDs), such as hypertension, diabetes, cardio-cerebrovascular (CCVD), in same individual, has emerge a significant global health concern due population aging. Although previous research demonstrated association between air pollutants, evidence on link CMM pollution exposure among Chinese older adults is limited. To address this gap, we conducted national representative survey...
To date, no study has explored the extent to which genetic susceptibility modifies effects of air pollutants on risk atrial fibrillation (AF). This was designed investigate separate and joint long-term exposure AF events. included 401,251 participants without at baseline from UK Biobank. We constructed a polygenic score categorized it into three categories. Cox proportional hazards models were fitted assess genetics AF. Additionally, we further evaluated effect modification susceptibility....
We aimed to investigate the association of regular opioid use, compared with non-opioid analgesics, incident dementia and neuroimaging outcomes among chronic pain patients.
Abstract Background Over the past three decades, China has experienced significant changes in urban-rural, gender, and age-specific suicide mortality patterns. This study aimed to investigate long-term trends from 1987 2020. Methods Suicide data were obtained China’s National Health Commission. Joinpoint regression analysis was used examine age-period-cohort modeling estimate age, period, cohort effects on Net drift, local longitudinal age curves, period relative risks also calculated....
<sec>Introduction<p>Ambient fine particulate matter pollution (PM<sub>2.5</sub>) has been widely associated with cardiovascular disease (CVD). However, less is known about the contribution of different chemical components PM<sub>2.5</sub> to CVD using a nationally representative sample in China. </p></sec><sec>Methods<p>A older adults was recruited from 31 provinces, municipalities, or autonomous regions China by fourth national...
Fine particulate matter, known as PM2.5, is recognized a risk factor for dementia. However, the specific linkage between PM2.5 constituents and dementia not well understood. We conducted cohort of 217,336 participants UK Biobank to explore association long-term exposure with all-cause dementia, Alzheimer's disease (AD), vascular estimated based on residential addresses by an evaluation model used time-varying Cox models Quantile g-computation assess effects individual their mixtures. Genetic...
China has the highest number of new cancer cases and deaths worldwide, posing huge health economic burdens to society affected families. This study comprehensively analyzed secular trends national mortality statistics inform future prevention intervention programs in China.