A5062362964- Dermatology and Skin Diseases
- Asthma and respiratory diseases
- Cleft Lip and Palate Research
- Breastfeeding Practices and Influences
- Infant Nutrition and Health
- Gut microbiota and health
- Oral microbiology and periodontitis research
- Pediatric health and respiratory diseases
- Allergic Rhinitis and Sensitization
- Neonatal Respiratory Health Research
- Energy and Environment Impacts
- Hybrid Renewable Energy Systems
- Air Quality and Health Impacts
Chinese University of Hong Kong
2021-2023
Prince of Wales Hospital
2021-2023
The health benefits of breastfeeding are partly contributed by human milk oligosaccharides (HMOs), but there is limited data on breast (BM) HMO composition in Chinese.This study investigated the association between early-life intake and allergy occurrence Chinese children.103 healthy pregnant women regardless history were recruited into this birth cohort. Their babies followed until 24 months old. Concentrations 2'-fucosyllactose (2'-FL), lacto-N-neotetraose (LNnT), -sialyllactose (3'-SL)...
Eczema is a common inflammatory skin disorder during infancy. Evidence has shown that skin-microbiome fluctuations may precede eczema development, but their predictive value for phenotypes remains unknown. We aimed to investigate the early-life evolution of microbiome and its temporal associations with different pairs (transient versus persistent, atopic non-atopic) in Chinese children. followed 119 term infants from birth 24 months old within Hong Kong cohort. The microbes at left...
<b>Carbonaceous particles seen in frozen human macrophage-enriched placental cells can be used as a biomarker of personal exposure to combustion-derived particulate matter. The feasibility using tissues will allow for global comparative studies.</b>https://bit.ly/3yANbRi
<h3>Background</h3> Eczema is a common skin inflammatory disorder during infancy. An increasing number of studies have shown an association between eczema and microbiome fluctuations. Skin dysbiosis was reported to precede the onset infant by both culture-based sequencing-based analyses. However, pathophysiology highly complex heterogenous. Given that umbrella term for atopic (IgE-associated) non-atopic (non-IgE-associated) forms eczema, whether plays important role in determining subtypes...
<h3>Background</h3> Eczema is a common skin inflammatory disease during infancy. Most paediatric patients develop eczema within 6 months of age, but the severity and persistence vary. While infantile in most cases could improve or get resolved with some children may follow relapsing persistent course. The underlying decisive early-life factor not yet known. An increasing number studies have shown an association between microbiome fluctuations. Evidence has revealed gut eczema, currently...