I. A. Lyagina

ORCID: 0000-0001-5434-9062
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About
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Research Areas
  • Gut microbiota and health
  • Clostridium difficile and Clostridium perfringens research
  • Inflammatory Bowel Disease
  • Digestive system and related health
  • Pharmacological Effects of Natural Compounds
  • Colorectal Cancer Screening and Detection

State Scientific Center of Coloproctology
2021-2022

Background. The intestinal microbiota, on the one hand, protects a person from pathogens, other it itself may be of triggers and/or mediators progression in inflammatory bowel diseases. Inflammatory disease (IBD) predominantly affects young people working age. It noted steady increase incidence IBD recent decades throughout world and Russia. diseases significantly affect quality life lead to complications having perform surgery, which reduces life. Aims study was investigate composition...

10.15690/vramn1480 article EN cc-by-nc-nd Annals of the Russian academy of medical sciences 2022-07-31

The aim of the review is to show possible links between intestinal microbiota and colorectal carcinogenesis, describe procarcinogenic properties microorganisms associated with development or proliferation cancer. gut plays a leading role in metabolism, providing important metabolites macroorganism. In humans, there spatial variability qualitative quantitative composition. provides colony resistance, protecting it from colonization by opportunistic pathogenic microorganisms. There more data...

10.33878/2073-7556-2021-20-1-68-76 article EN Koloproktologia 2021-03-18

Aim. Study of the dynamics changes in intestinal microbiota patients with Clostridioides difficile-associated infection. Materials and methods. The study included 746 inpatient treatment. 502 were examined at stage admission discharge from hospital, 305 clinical picture infection (CDI), among them 163 (46.6%) men 142 (53.4%) women. age was 48-67 years. qualitative quantitative composition translucent feces investigated. Results. Analysis fecal treated a coloproctology hospital showed colonic...

10.31146/1682-8658-ecg-160-12-51-57 article EN cc-by Experimental and Clinical Gastroenterology 2018-12-01
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