Abstract Background It is known that patients with sickle cell disease ( SCD ) present activation of the blood coagulation and fibrinolytic systems, especially during vaso‐occlusive crises also steady state disease. We determined whether presence factor prothrombin gene G 20210 A variant, V 1691 mutation (factor L eiden), methylenetetrahydrofolate reductase MTHFR C 677 T polymorphisms may be risk factors for vascular complications in individuals . Methods The study involved 150 anemia...

The clinical manifestation in sickle cell disease (SCD) patients varies from one individual to another due factors like the presence of alpha-thalassaemia mutation, foetal haemoglobin, and β-globin gene haplotype. present study enumerates profile anaemia Central India.Seven hundred seventy-six SCD Jabalpur surrounding districts (Madhya Pradesh) central India were registered with clinic NIRTH, Jabalpur. reveals recorded signs symptoms genetically confirmed (404) beta thalassaemia (92)...

Introduction: The aim of this study was to examine the effect Allium sativum (garlic) extract on biofilm formation by Streptococcus mutans surface orthodontic mini-implants. Materials and Methods: Three brands (Dentos, Forestadent Hubit) titanium mini-implants were used as samples, which divided into four groups each containing S. along with different concentrations garlic extract-0 mg/ml, 16 32 64 mg/ml 1 mini-implant from three brands. amount viable bacteria, well its determined...

Introduction: The transverse dimension plays a key role in smile. Maintaining the pretreatment arch form is to obtaining stable results. Objectives: main aim of this study was determine mean intercanine width and intermolar Angle’s class I patients. Methods: Seventy-six casts were obtained from records patients who sought orthodontic treatment Orthodontics Dentofacial Orthopedics. Four parameters used namely; maxilla mandible. Linear measurements carried out with digital caliper. Kappa test...

Introduction: Malocclusion is a malrelationship between the arches in any of planes or which there are anomalies tooth position beyond normal limits. The epidemiological data has key role planning varies among different countries, ethnic groups and age groups. Aims objective: To find out prevalence malocclusion medical students IOM.
 Materials method: Quantitative, cross-sectional descriptive study MBBS Maharajgunj Medical Campus from first year to final was done; participating...

Mixed dentition space analysis forms an important part of orthodontic diagnosis and treatment planning. Regression equations are widely used for mixed which can vary among races. This study aimed to find out the new regression equation in estimating size unerupted canines premolars Nepalese Brahmins/Chhetris. Hundred Brahmins/Chhetris (50 males 50 females) who met our criteria were selected patients attending Orthodontic Out-Patient Department, Institute Medicine, Kathmandu. The mesiodistal...

Assessment of growth status a patient is key component in orthodontic diagnosis and treatment planning for growing patients with skeletal discrepancy. Skeletal maturation based on hand-wrist radiograph cervical vertebral (CVM) are commonly used methods assessment. Studies have shown that stages dental calcification can also be to assess an individual, whereas other studies suggested the relationship between should interpreted caution owing racial variation.To evaluate permanent mandibular...

Introductions: Congenital malformations need to be identified and intervened early save lives prevent sufferings. Many birth defects have well known incidence/prevalence rates but these not been studied thoroughly in the local population of Nepal. The current study was undertaken determine prevalence congenital malformation at birth, classify them systematically, risk factors immediate outcome newborn babies afflicted.Methods: This a cross sectional study. All newly delivered were examined...

The aim of this study was to evaluate and compare the effect different methods recycling stainless steel orthodontic brackets on shear bond strength.One hundred twenty human premolars extracted for purpose were randomly divided into four groups. Standard MBT (0.022″) bonded buccal surface all samples with light cured adhesive primers using an LED curing unit 10 seconds. Group I assigned as control, II, III, IV subjected by flaming, flaming sandblasting, ultrasonic cleaning, respectively....

Background: Human immunodeficiency virus (HIV) and hepatitis B (HBV) are global health concerns. Due to shared routes of transmission, co-infection is common. Their co-existence can cause severe liver complications immunological impairment in infected individuals. Aim: To find the prevalence HBV HIV patients assess pattern enzymes CD4 T-cell counts monoinfected HIV/HBV co-infected patients. Materials Methods: A total 342 consecutive confirmed positive treatment naïve were tested for surface...

The prevalence of skeletal Class II malocclusion is high amongst Asian population. Various treatment modalities have been presented for the malocclusions in adult patients. We come across many patients who desire a costeffective and non-surgical correction they accept dental camouflage as option to mask discrepancy. This case report presents 26-year-old non-growing female had with prognathic maxilla retrognathic mandible an overjet 7 mm, severe crowding, but did not want surgical treatment....

Introduction: The objective of this study was to investigate the need orthodontic treatment among young Nepalese adults by determining and comparing threshold esthetic impairment where would be sought a sample Dental Nursing students. Methods: Using 10-grade component (AC) scale Index Orthodontic Treatment Need (IOTN), 250 university students (100 dental 150 nursing students) selected level that represented point at which they seek treatment. A questionnaire answered both populations....

Background: Group B Streptococcus (GBS) is a Gram-positive bacterium that can cause sepsis and meningitis in newborns, often transmitted from mother to baby during childbirth. About 20-30% of women carry GBS, with 50-70% their infants becoming colonized delivery. GBS lead neonatal sepsis, pneumonia, or meningitis. Early-onset occurs delivery, while late-onset environmental sources. Preventive measures include screening pregnant for administering antibiotics labor. This study aims assess the...

Objectives: Tobacco consumption is mainly done in two forms, smoked tobacco and smokeless tobacco. This study was carried out to determine the negative effects of cigarette smoking, bidi chewing on haematological parameters establish a link between them. Material methods: A matched comparative cross-sectional Upgraded Department Physiology partnership with Medicine at SMS Medical College, Jaipur. The included 210 apparently healthy people (70 smokers, 70 chewers, non-tobacco users). Blood...

Background: A pleasing face requires symmetry in all three planes. Abnormality the symmetric growth of condyles is one most common causes facial asymmetry. Aims and Objective: The objective this study was to determine vertical mandibular condyle asymmetry different skeletal patterns among genders. Materials Method: Pre-treatment lateral cephalograms 102 subjects (equally divided into groups: Class I, II III) seeking orthodontic treatment were used condylar Condylar determined by comparing...

IntroductionWith the advancement of soft tissue paradigm, various factors have been added to orthodontic problem list for diagnosis and treatment planning. This study aimed examine dimensions facial tissues alongside cephalometric parameters in patients. MethodsThis observational was conducted at Department Orthodontics dentofacial orthopedics, TUTH. Three different groups based on morphological patterns (brachyfacial, dolichofacial, mesofacial) with upper lip thickness (ULT), lower (LLT),...