A5068138489- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Health and Technologies
- Ovarian function and disorders
- Forensic and Genetic Research
- Molecular Biology Techniques and Applications
- Sperm and Testicular Function
- Reproductive System and Pregnancy
- Reproductive Health and Contraception
- Pregnancy and preeclampsia studies
- Ovarian cancer diagnosis and treatment
- Genetic Associations and Epidemiology
- Prenatal Screening and Diagnostics
- Endometriosis Research and Treatment
- Systemic Lupus Erythematosus Research
- T-cell and B-cell Immunology
- Race, Genetics, and Society
- Ocular Diseases and Behçet’s Syndrome
- Immune Cell Function and Interaction
- Hematopoietic Stem Cell Transplantation
- Demographic Trends and Gender Preferences
- Renal Diseases and Glomerulopathies
- Birth, Development, and Health
- Renal and related cancers
- Animal Genetics and Reproduction
Universidade de Santiago de Compostela
2008-2025
Universidad de Costa Rica
2005-2025
Instituto Nacional del Cáncer
2023
Centre d'Higiene Mental Les Corts (Spain)
2016-2019
University of Córdoba
2015
Fundación Pública Galega de Medicina Xenómica
2008
Centro Regional de Derechos Humanos y Justicia de Género, Corporación Humanas
1992
Hospital Universitario de Maracaibo
1983
University of California, Los Angeles
1983
Instituto Venezolano de Investigaciones Científicas
1983
Is oral medroxiprogesterone acetate (MPA) non-inferior compared to ganirelix with respect the number of mature oocytes (MII) retrieved at ovum pick-up (OPU) in oocyte donation cycles?MPA is comparable terms MII OPU cycles.Oral treatment MPA inhibits pituitary LH surge during ovarian stimulation infertile patients. Because its negative effect on endometrium, suppression combined freeze-all. Published reports indicate that both and pregnancy rates from these are short protocol GnRH agonists...
Abstract STUDY QUESTION Are phospholipase C zeta 1 (PLCZ1) mutations associated with fertilization failure (FF) after ICSI? SUMMARY ANSWER New in the PLCZ1 sequence are FFs ICSI. WHAT IS KNOWN ALREADY FF occurs 1–3% of ICSI cycles, mainly due to oocyte activation (OAF). The sperm PLCζ/PLCZ1 protein hydrolyzes phosphatidylinositol (4, 5)-bisphosphate oocyte, leading intracellular calcium release and activation. To date, few point causing decreased levels or activity have been linked FF....
Abstract STUDY QUESTION Does the diagnosis of mosaicism affect ploidy rates across different providers offering preimplantation genetic testing for aneuploidies (PGT-A)? SUMMARY ANSWER Our analysis 36 395 blastocyst biopsies eight laboratories revealed that euploidy were significantly higher in reporting low mosaicism. WHAT IS KNOWN ALREADY Diagnoses consistent with chromosomal have emerged as a third category possible embryo outcomes following PGT-A. However, era mosaicism, selection has...
Is there a difference in live birth rates following endometrial preparation with either constant or increasing estrogen dose fresh embryo transfer from oocyte donation cycles?There is no between versus an of after cycles oral transdermal supplementation.Endometrial (EP) and progesterone, embryo-endometrial synchronicity are determinant for adequate implantation. Estrogen crucial different exogenous administration patterns could imply variations on EP. Moreover, undergoes metabolization by...
Does time to ICSI affect reproductive outcomes?Biochemical and clinical pregnancy diminish progressively as between oocyte pick up (OPU) increases after fresh embryo transfer.Appropriate cytoplasmic nuclear maturation are of paramount importance ensure an optimal embryonic developmental competence. While is usually attained by the reaches OPU, cannot be readily assessed might incomplete. On other hand, excessive in vitro culture mature human oocytes can their ultrastructural characteristics...
Is oocyte vitrification/warming as efficient and effective using fresh oocytes in donation cycles?IVF with vitrified donor is less than oocytes, but its efficacy remains comparable to that of cycles.Oocyte vitrification used preserve the reproductive potential oocytes. A small number randomized controlled trials carried out by experienced groups have shown this technique provides fertilization, pregnancy, implantation ongoing pregnancy rates those However, large registry-based analyses...
Do culture conditions affect cytoplasmic maturation in denuded immature non-GV oocytes?The rate of oocytes is not affected by media, but vitro seems to alter the mitochondrial membrane potential, endoplasmic reticulum (ER) and actin cytoskeleton compared with vivo maturation.In benefits cycles poor MII oocyte collection, levels are only scored polar body extrusion. Since involves nuclear as well for full meiotic competence, further knowledge needed about culture.This basic research study was...
Does sperm cryopreservation influence the reproductive outcomes of normozoospermic patients in oocyte donation cycles?After controlling for confounders, use cryopreserved semen from does not affect pregnancy and live birth rates after elective ICSI.Sperm by slow freezing is a common practice ART. While frozen-thawed typically presents reduced motility vitality, its ICSI generally considered adequate terms outcomes. Nevertheless, most studies comparing between fresh include with severe male...
Three-dimensional (3D) sonographically based automated volume calculation (SonoAVC; GE Healthcare, Zipf, Austria) is being introduced in folliculometry during ovarian stimulation; however, clear training assessments this technique are lacking. The learning curve-cumulative summation (LC-CUSUM) test provides a quantitative tool to determine when trainee has learned procedure. aim of prospective study was assess 3D SonoAVC LC-CUSUM curves folliculometry.Analyses were performed on 98 oocyte...
What is the clinical efficacy of an oocyte donation program based on transportation frozen semen and embryos between two countries?The transnational efficient reliable it could provide a first-line strategy to overcome lack donors in some countries.While there increasing need for donated oocytes, many countries availability still insufficient cover therapeutic demands, patients are referred abroad treatment. Since embryo cryopreservation efficient, we propose instead oocytes satisfy demand...
Can two different methods for oocyte vitrification, one using an open tool and the other a closed tool, result in similar survival rates? The rate was found to be higher method. Open vitrification is performed routinely donation cycles. Closed may slower cooling rates thus it less used, even though has been recommended order avoid risk of cross-contamination between material from patients. This prospective cohort study with sibling oocytes carried out fertility center July 2014 January 2016....
Unexplained fertilization failure (FF), occurring in 1-3% of intracytoplasmic sperm injection (ICSI) cycles, results both psychological and financial burden for the patients. However, molecular causes behind FF remain largely unknown. Mass spectrometry is a powerful technique to identify quantify proteins across samples; however, no study so far has used it dissect proteomic signature spermatozoa with after ICSI.To investigate whether samples from patients suffering repetitive ICSI display...