- Pregnancy and preeclampsia studies
- Anesthesia and Pain Management
- Birth, Development, and Health
- Nausea and vomiting management
- Pain Management and Opioid Use
- Anesthesia and Neurotoxicity Research
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Sedative Agents
- Respiratory Support and Mechanisms
- Electrolyte and hormonal disorders
- Neonatal Respiratory Health Research
- Cardiac electrophysiology and arrhythmias
- COVID-19 epidemiological studies
- ECG Monitoring and Analysis
- Intensive Care Unit Cognitive Disorders
- Insurance, Mortality, Demography, Risk Management
- Maternal and fetal healthcare
- Family and Patient Care in Intensive Care Units
- Magnesium in Health and Disease
- Airway Management and Intubation Techniques
- Data-Driven Disease Surveillance
- Sympathectomy and Hyperhidrosis Treatments
- Phonocardiography and Auscultation Techniques
- Pain Mechanisms and Treatments
- Inflammatory Myopathies and Dermatomyositis
University of Ghana
2016-2025
Korle Bu Teaching Hospital
2013-2024
Background: A large percentage (16% of maternal mortality in developed countries, compared to 9% developing countries), is due hypertensive disorders pregnancy. The etiology preeclampsia remains unknown, with poorly understood pathophysiology. Magnesium and calcium play an important role vascular smooth muscle function therefore a possible the development preeclampsia. Aim: We aimed compare serum magnesium total levels preeclamptic normal pregnant women at Korle-Bu Teaching Hospital Ghana....
The incidence of Tuberculosis (TB) differs among countries and contributes to morbidity mortality especially in the developing countries. Trends seasonal changes number patients presenting with TB have been studied worldwide including sub-Saharan Africa. However, these are unknown at Korle-Bu Teaching Hospital (KBTH). aim this study was obtain a time series model estimate cases chest clinic hospital.A analysis using Box-Jenkins approach propounded as an autoregressive moving average (ARIMA)...
Pregnancy is associated with significant changes in maternal cardiovascular system which regulates oxygen and nutrient supply to the growing foetus. Nitric oxide, a physiologic vascular smooth muscle relaxant blood flow therefore may play role pregnancy. The study aimed determine levels serum nitric oxide during healthy pregnancy.A case-control was conducted among 32 non-pregnant women as controls 100 pregnant (consisting of 33 first trimester, 37 s 30 third trimester) cases. Subjects were...
Background: Preeclampsia remains a poorly understood complication of pregnancy affecting 5–14% pregnancies worldwide. Recent studies indicate that serum electrolytes may play role in preeclampsia since it is vascular endothelial disorder. Aim: To compare sodium and potassium levels between preeclamptics normotensive pregnant women tertiary hospital Ghana. Methods materials: This was case-control study consisting 30 recruited consecutively at their first third trimester pre-natal visit...
Background: Anaesthesia has always been misconstrued as a 'behind the scenes' specialty. Despite advancements in anaesthesia, there is inadequate public knowledge regarding specialty, scope of functions anaesthetists, and pivotal role anaesthetists play healthcare delivery system. This study therefore assessed perception anaesthesia among patients tertiary facility.Methods: A cross-sectional was conducted over 3 months 2015 279 accessing services at pre-anaesthetic clinic Korle-Bu Teaching...
BACKGROUND: Preeclampsia is one of the commonest aetiologies foetal and maternal mortality morbidity. Though common, aetiology preeclampsia has remained unknown with several inconclusive theories surrounding disease. Recent studies have implicated vascular endothelial dysfunction possibly nitric oxide in preeclampsia.AIM: To compare plasma levels pre-eclampsia healthy pregnant women a large tertiary hospital Ghana.METHODS: This was case-control study conducted among Korle-Bu Teaching...
Pregnancy is described as a normal physiologic state associated with various biochemical changes. Magnesium and calcium are essential macronutrients required for foetal growth. Complications their deficiency during pregnancy include; low neonatal birth weight, pre-eclampsia, eclampsia preterm labour. Changes in serum levels of magnesium have not been extensively studied among Ghanaian women.To determine the variation gestational age women.A hospital-based comparative cross-sectional study...
Idiopathic scrotal calcinosis is a rare condition, characterized by the idiopathic deposition of calcium in dermis leading to formation single nodule or multiple nodules different sizes. Surgical excision reduces symptoms and improves cosmesis. We present case that had an en bloc skin primary closure skin. Handling each hemiscrotum as separate entity preserving median raphe with its uninvolved improved Reported outcomes surgery were satisfactory no postoperative complications. At 30 months...
Potassium and magnesium are the two most abundant intra-cellular cations. They play pivotal roles in many essential biological processes. Deficiencies of these electrolytes clinical importance hospitalised patients.To determine relationship between serum total potassium levels adult patients requiring an emergency intra-abdominal surgery utility this care patients.A cross sectional study was conducted over a five month period at Korle-Bu Teaching Hospital. All 101 admitted for surgery, who...
Background: Specialisation is perceived as essential for success, and affects the availability distribution of medical personnel quality service health system able to deliver. In Ghana, some areas specialties have a relatively good number practitioners are constantly attracting prospective doctors into these fields. Anaesthesia, which an integral part care system, one field with inadequate workforce has been few specialty.
Introduction: The use of ultrasound in anaesthetic practice continues to be more established and the guidance establishing vascular access is recommended by various groups. We have developeda tissue model for skills development access.Method: consist a piece “pork belly”, longitudinal shaped balloon inserted between two muscle layers at chosen depth (mimics blood vessel), bag intravenous fluid (e.g. Ringer’s Lactate) together with giving set short extension tubing connected threeway tap used...
Background: Maintenance of optimal Endotracheal Tube cuff Pressure (ETTcP) in anaesthetic practice reduces pressure complications. Aneroid manometers for measurement ETTcP are not widely available Ghana, hence anaesthesia providers estimate according to their experience. The study assessed obtained from estimation techniques between at Korle-Bu Teaching Hospital (KBTH). It also evaluated the Volume Air Required (VAR) obtain an acceptable inflation sizes 7.0 and 8.0 mm adult endotracheal...
Objectives: Dexamethasone has beneficial effects on postoperative nausea and vomiting, however, many clinicians have raised legitimate concerns regarding its effect blood glucose concentrations. This study determined the safety efficacy of a single pre-operative dose dexamethasone for PONV prophylaxis in patients undergoing breast surgery.
 Design: Prospective, double-blind, placebo-controlled trial
 Setting: Surgical wards Korle-Bu Teaching Hospital, Accra, Ghana
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Magnesium is the second most abundant intracellular cation and a co-factor in several reactions involved formation usage of adenosine triphosphate nucleic acid synthesis. deficiency may be as high 65 % patients admitted to medical Intensive Care Unit (ICU). Significant potentially fatal conditions have been attributed hypomagnesaemia it has also associated with poor prognosis increased mortality critically ill. The study aimed determine prevalence identify predictive factors preoperative...
Abstract Background Management of life-threatening arrhythmia can be incredibly challenging in advanced health systems. In sub-Saharan Africa (SSA), this is likely more because weak pre-hospital and in-hospital critical care Little known about their outcomes SSA. The aim study was to examine the types arrhythmias among haemodynamically unstable patients presenting at a tertiary hospital Accra-Ghana. Method This retrospective case series conducted Korle-Bu Teaching Hospital (KBTH), Medical...
treatment of severe burn injury generally requires enormous human and material resources including specialized intensive care, staged surgery, continued restoration. This contributes to the burden on patients their families. The cost is influenced by many factors demographic clinical characteristics patient. study aimed determine costs care its associated predictive in Korle-Bu Teaching Hospital, Ghana.
Background Pain after breast surgery has been described as moderate to severe in intensity and, if inadequately treated, increases postoperative morbidity, hospital cost, and the incidence of persistent pain. Serratus anterior plane (SAP) block is an interfascial injection technique for analgesia chest wall. There a lack data with regard its analgesic possible opioid-sparing effects Sub-Saharan Africa. This study aimed determine perioperative effect serratus administered surgery. Methods was...
Breast surgery may be associated with significant postoperative pain and if not adequately treated, lead to the development of chronic post-surgical pain. This necessitates use effective management, involving a multimodal analgesia regimen for management post breast The analgesic effect perioperative dexamethasone has been explored but findings have inconsistent.The aim this study was determine enhancing single preoperative dose on patients undergoing at tertiary hospital in Ghana.This...
Background: Many studies have reported on trifecta outcomes after radical prostatectomy. There is however paucity of that compares the outcome between screen detected and patients presenting with lower urinary symptoms localized prostate cancer This study these two groups an open retropubic Methodology: a retrospective study, (urinary continence, erectile function, control) consecutive had prostatectomy for by single surgeon. Patients were grouped into presentation or retention urine. The...
Background: Chronic exposure to inhaled anaesthetic agents poses an occupational hazard related the practice of anaesthesia. Therefore, this study sought find out perception anaesthesia providers on inhalational anaesthetics, evaluate their knowledge effects chronic and strategies reduce operating room agents. Method: This cross-sectional survey was conducted by administering a self-administered questionnaire 71 in Ghana who attended annual refresher course faculty Anaesthesia, West African...
BACKGROUND: Premedication is helpful especially in children reducing the stress associated with anesthesia and surgery. Pediatric patients for surgery Korle Bu Teaching Hospital are currently not sedated preoperatively due to unavailability of effective pediatric sedative preparations. Ketamine readily available, inexpensive, has been used sedation through various routes good outcomes other geographical regions. Its intra-nasal use shows promise avoids anxiety pain establishing an...