A5081519704- Malaria Research and Control
- Mosquito-borne diseases and control
- Invertebrate Immune Response Mechanisms
- Escherichia coli research studies
- Bacterial Genetics and Biotechnology
- Antibiotic Resistance in Bacteria
- Complement system in diseases
- Innovations in Medical Education
- Aquaculture disease management and microbiota
- Microbial Inactivation Methods
- Viral gastroenteritis research and epidemiology
- Medical Education and Admissions
- Listeria monocytogenes in Food Safety
- Vector-borne infectious diseases
- Diversity and Career in Medicine
- Vibrio bacteria research studies
- Essential Oils and Antimicrobial Activity
Deakin University
2022
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini"
2020
The University of Melbourne
2006-2012
Royal Children's Hospital
2006
Murdoch Children's Research Institute
2006
Walter and Eliza Hall Institute of Medical Research
2000-2002
The Royal Melbourne Hospital
2000
ABSTRACT Enteropathogenic Escherichia coli (EPEC) is a major cause of diarrhea in infants developing countries. We have identified functional type II secretion system (T2SS) EPEC that homologous to the pathway responsible for heat-labile enterotoxin by enterotoxigenic E. . The wild-type T2SS was able secrete reporter, but an isogenic mutant could not. showed substrate SslE, outer membrane lipoprotein (formerly known as YghJ), and essential biofilm formation EPEC. SslE mutants were arrested...
The gene cluster gspCDEFGHIJKLM codes for various structural components of the type II secretion pathway which is responsible heat-labile enterotoxin by enterotoxigenic Escherichia coli (ETEC). In this work, we used a variety molecular approaches to elucidate transcriptional organization ETEC system and unravel mechanisms expression these genes controlled. We showed that three other upstream genes, yghJ, pppA, yghG, are cotranscribed promoter located in region yghJ plays major role 14-gene...
ABSTRACT The low-molecular-mass rhoptry complex of Plasmodium falciparum consists three proteins, rhoptry-associated protein 1 (RAP1), RAP2, and RAP3. genes encoding RAP1 RAP2 are known; however, the RAP3 gene has not been identified. In this study we identify from P. genome database show that is part complex. Disruption demonstrated it essential for merozoite invasion, probably because can complement loss homology with encoded on chromosome 5 in a head-to-tail fashion. Analysis databases...
Malaria is a major human health problem and responsible for over 2 million deaths per year. It caused by number of species the genus Plasmodium, Plasmodium falciparum causative agent most lethal form. Consequently, development vaccine against this parasite priority. There are stages life cycle that being targeted vaccines. Important candidate antigens include proteins on surface asexual merozoite stage, form invades host erythrocyte. The methods to manipulate genome has enabled construction...
Given the importance of selection process, many medical schools are reviewing their criteria. The traditional pathway for post-graduate medicine has been from science-based undergraduate degrees, however some programs expanding In this study we investigated academic success across all years and themes Deakin University degree, based on type degree undertaken prior to admission. We evaluated whether biomedical science into should remain choice, or other disciplines be encouraged.Data 1159...
Conference Abstract| October 01 2000 Identification and functional analysis of proteins involved in the invasion human erythrocytes by malaria parasite Plasmodium falciparum A. F. Cowman; Cowman 1The Walter Eliza Hall Institute Medical Research, Melbourne 1050, Australia Search for other works this author on: This Site PubMed Google Scholar M. B. Reed; Reed T. Triglia; Triglia J. K. Thompson; Thompson D. L. Baldi; Baldi Healer; Healer R. O'donnell; O'donnell 2Department Microbiology...