- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Axon Guidance and Neuronal Signaling
- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Breast Cancer Treatment Studies
- Cancer-related cognitive impairment studies
- Cervical Cancer and HPV Research
- Mesenchymal stem cell research
- Infection Control and Ventilation
- Molecular Biology Techniques and Applications
- Bone health and treatments
- Reconstructive Surgery and Microvascular Techniques
- Hematological disorders and diagnostics
- Wound Healing and Treatments
- RNA modifications and cancer
- Brain Metastases and Treatment
- FOXO transcription factor regulation
- Lymphatic System and Diseases
- BRCA gene mutations in cancer
- Genetic factors in colorectal cancer
- Colorectal and Anal Carcinomas
Kocaeli Üniversitesi
2017-2025
Background: One of the most significant long-term toxicities breast cancer radiotherapy is major adverse cardiac events (MACE). In current practice, mean heart dose commonly used parameter. The aim our study was to reduce doses organs at risk (OAR) in left anterior descending artery (LAD) and ventricle (LV) by including LAD LV planning while maintaining adequate coverage for patients with left-sided cancer. Methods: We retrospectively analyzed cases treated Kocaeli University Faculty...
Tissue ischemia and necrosis following surgery after radiotherapy on the skin subcutaneous tissue are well known to all reconstructive surgeons. Nevertheless, there has been no report so far local effects of adipose-derived stem cells (ADSCs) random flap survival elevated in an irradiated rat dorsum. In this experimental study, we aimed identify effect adipose tissue-derived cell injection tissues.Adipose-derived were isolated from groin region Sprague-Dawley rats expanded ex vivo for 3...
Exercise is a nonpharmacological supportive therapy which has been specifically identified to reduce postoperative complications or adverse events of cancer treatments. Although there are few studies combining resistance and aerobic exercise in survivors, programs very rare different places the literature. This study aims investigate effects mixed-type venues on weight, body mass index, fatigue, quality life survivors.This descriptive, intervention study. Participants were included study,...
At present, there are few biomarkers used to predict the prognosis of uterine serous carcinoma (USC). Netrin-1 may be a promising biomarker candidate. We investigated netrin-1 expression in USC tissues and healthy endometrial determine its relevance disease prognosis.
<title>Abstract</title> <bold>Purpose:</bold>To show the impact of patient coaching and home practice using deep inspiration breath hold (DIBH) technique on radiation treatment set-up times cardiac at-risk doses. <bold>Methods:</bold>The study involved patients who received tangential field radiotherapy DIBH for treating left breast cancer. Patients were divided into two groups: first group consisted those from an oncology nurse given instruction sheet at least 1 week before computed...
Objective: To retrospectively determine the long-term outcome of adult intracranial and spinal ependymoma patients treated with postoperative radiation therapy after surgery. Methods: Fourteen who underwent radiotherapy surgery at a single center between 1999 2022 were included. The endpoints analyzed overall survival progression-free survival, together prognostic factors. Results: median (range) age was 29.5 (23–58) years. majority (71.4%) tumors located in canal gross total resection...
The aim of this study is to investigate the rational effects packing, which has seen reduced use after introduction fixators that perform stabilization function-on rectum, bladder, and A point doses when used in conjunction with fixators.
Flexible manufacturing systems have been widely used especially in the field of medicine to develop personal protective types equipment such as ventilator components or sample collection apparatuses except face visors and masks/respirators during fight against pandemic. In this study, an N95 derivative respirator was designed based on FDM technology then compared with similar known mask models literature terms costs functionality. Optimization carried out printing parameters improve speed...
Background/Objectives: Few biomarkers are used to predict the prognosis of serous uterine carcinoma (USC). Netrin-1, may be a promising biomarker candidate. Our aim was investigate netrin-1 expression in USC tissues and analyze its relevance with disease prognosis. Material Methods: The 48 patients’ examined by immunohistochemistry. Results: overall positivity rate 76%, detected as high 17 (35%), low 19 (40%) patients. Patients suffering from tumors no (n= 15) had median OS 60.0 months (95%...
Objective: Progress in therapy of childhood non-Hodgkin lymphoma (NHL) is one the stunning success stories past two decades. In developed countries, more than 80% children with NHL can now be cured modern therapy, even patients widely disseminated disease. The aim this study to analyze all who were treated a single tertiary center Turkey. Methods: An analysis data NHL, diagnosed and between 2003 2012 according original Berlin-Frankfurt-Munster (BFM) protocol Kocaeli University Pediatric...
This study presents the joint experience of three centers in treatment patients with biliary tract tumors radiation therapy (RT).The records 27 were retrospectively reviewed. All who had undergone surgical resection received postoperative adjuvant RT, whereas all not a RT palliative intent. Twenty adequate performance status treated and chemotherapy, while remaining seven alone.Follow-up ranged from 1 to 44 months. Local control was achieved 10 out 11 Systemic failure observed eight at 5 16...
Breast cancer is the most prevalent malignancy in women worldwide. Although pathogenic variants BRCA1/2 genes are responsible for majority of hereditary breast cases, a substantial proportion patients negative variations these genes. In cancers, signal transduction pathways cell usually affected first. Therefore, this study aimed to detect and classified genetic non-BRCA signaling investigate underlying causes susceptibility cancer.Ninety-six without who met inclusion criteria were enrolled...