A5010937804- Neurological Disorders and Treatments
- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Acute Ischemic Stroke Management
- Neuroinflammation and Neurodegeneration Mechanisms
- Social and Behavioral Studies
- Medical and Pharmaceutic Studies
- Neurological Disease Mechanisms and Treatments
Clinical Hospital No. 8
2024
Ural State Medical University
2020-2022
Macular diseases are traditionally a serious issue in ophthalmology, which has great social impact due to widespread occurrence and significant vision loss, often irreversible. Over the past few decades, possibilities for diagnosis treatment of pathologies retina choroid have been significantly expanded. Randomized clinical trials provided ophthalmologists with valuable information on natural course strategies common retinal from viewpoint evidence-based medicine. However, large number...
Neuroinflammation during intracerebral hemorrhage is initiated by blood breakdown products in the subarachnoid space and/or brain parenchyma. In this case, neuroinflammation can cause development of systemic inflammation. some cases, accompanied appearance phenomenon ineffective cerebral flow and clinical manifestations death. The purpose study to identify markers inflammation severe hemorrhagic stroke with or without effective flow. included patients presence multiple organ failure...
Increasing evidence suggests that stroke is a systemic disease affecting multiple organs. Systemic inflammatory response and immune dysregulation associated with hemorrhagic stroke, may play an important role in brain injury, its recovery, outcomes. However, it worth of note that, from our point view, the classical concepts about inflammation pathophysiology general pathology do not entirely meet needs modern medical practice. The existence this problem also typical for assessing...
Patients lost to follow-up (LTFU) are a well-recognized challenge, both in clinical trials and real practice. PURPOSE: To study the reasons for patients receiving anti-VEGF therapy «wet¼ age-related macular degeneration (wAMD) environment cease monitoring clinic. MATERIAL AND METHODS: This retrospective cohort included with wAMD which received (ranibizumab, aflibercept) Ural State Medical University clinic from 2011 2019 (n=241). A subgroup of continuing treatment (n=90) was compared follow...
Background.Anti-VEGF therapy is currently regarded as the gold standard for treatment of many macular diseases, while results its application in real clinical practice are often inferior to those from randomized trials.
 Materials and methods.A study group was formed on basis a retrospective analysis medical data patients who received anti-VEGF with ranibizumab and/or aflibercept according registered indications, discontinued their follow-up clinic (n= 214). A phone survey concerning...
Purpose: to study long-term (over a 60 months’ follow-up period) results of anti-VEGF therapy for macular diseases in real clinical practice. Materials and methods . We undertook single-center retrospective uncontrolled cohort 169 patients (109 women, men) who received eye (ranibizumab, aflibercept). The treatment started between May 2010 August 2015. group included 57 remained under regular observation months. Of these, 24 cases had “wet” age-related degeneration (wAMD), 20 myopic choroidal...
Purpose: to study long-term results of anti-VEGF therapy for macular diseases patients followed up 60 months in real clinical practice. Materials and methods. The research group included 57 (43 women, 14 men; median age 62 years) who received antiVEGF (ranibizumab, aflibercept) remained under regular observation months. Of these, 24 had “wet” agerelated degeneration (wAMD), 20 myopic choroidal neovascularization (mCNV), 10 edema due retinal vein occlusions (MERVO), 3 diabetic (DME)....
В статье рассматривается реализация суффиксальных деривационных моделей в рамках предметных жанров английской научной речи. Устанавливается зависимость выбора элементов от эпистемологической специфики конкретной дисциплины. Изучаются этимологические закономерности, стоящие за образованием терминологических дублетов, а также специализация того или иного суффикса и функции, приобретаемые ими конкретных дисциплинах. Исследуются случаи междисциплинарной внутридисциплинарной вариативности суффиксов.
Актуальность. Анти-VEGF терапия (от англ.vascular endothelial growth factor, VEGF – фактор роста эндотелия сосудов) является «золотым стандартом» лечения таких социально-значимых заболеваний макулы, как неоваскулярная («влажная»)возрастная макулярная дегенерация (вВМД), диабетический макулярный отёк (ДМО), вследствие окклюзии вен сетчатки (МООВС)и миопическая хориоидальная неоваскуляризация (мХНВ). Длительное регулярное наблюдение имеет решающее значение для достижения и сохранения...
Purpose. To summarize the results of our own studies that examined various aspects patient adherence to anti-VEGF therapy in routine clinical practice. Material and methods.In a performed from 2014 2021, retrospective analysis data was carried out, as well survey patients with macular diseases (637 total, including neovascular age-related degeneration – 554 cases) who received (ranibizumab, aflibercept) for registered indications. Results. The influence on treatment factors established,...