Vadim Ya. Krokhalev

ORCID: 0000-0003-1674-1957
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About
Contact & Profiles
Research Areas
  • Retinal Diseases and Treatments
  • Retinal and Optic Conditions
  • Neurological Disorders and Treatments
  • Characterization and Applications of Magnetic Nanoparticles
  • Healthcare Systems and Public Health
  • Retinal Imaging and Analysis
  • Bone health and osteoporosis research
  • Luminescence Properties of Advanced Materials
  • Glaucoma and retinal disorders
  • Dental Radiography and Imaging
  • Nuclear materials and radiation effects
  • Estrogen and related hormone effects
  • Sensor Technology and Measurement Systems
  • Non-Invasive Vital Sign Monitoring
  • Electrostatics and Colloid Interactions
  • Intraocular Surgery and Lenses
  • Optical Imaging and Spectroscopy Techniques
  • Foreign Language Teaching Methods
  • Solid-state spectroscopy and crystallography
  • Medical and Pharmaceutic Studies
  • Retinal and Macular Surgery
  • Cultural Competency in Health Care
  • Optical Coherence Tomography Applications
  • Social and Behavioral Studies
  • Minerals Flotation and Separation Techniques

Ural State Medical University
2012-2024

Relevance. Osteoporosis and chronic periodontitis are serious issues of modern life. The hypothesis that these two diseases associated is still open-ended doesn’t allow setting the record straight for lack sufficient evidence. Purpose. study aimed to detect relationship between periodontal health parameters mineral bone density characteristics in postmenopausal women. Material methods. examined 109 female patients with diagnosed moderate generalized (К05.31). participants formed groups: main...

10.33925/10.33925/1683-3759-2023-751 article EN cc-by Parodontologiya 2023-11-28

BACKGROUND: A widespread visual impairment among medical students is known, but there are no data on the ophthalmic status of clinical residents. AIM: To carry out an assessment analyzer in Russian universities graduates who begin residency according to specialty 31.08.59 Ophthalmology. MATERIALS AND METHODS: An anonymous residents’ online survey was conducted 15 from 14 cities using original interactive questionnaire. Responses were received 249 respondents (mostly females: n = 188, 75.5%;...

10.17816/ov634872 article EN Ophthalmology Reports 2024-12-30

BACKGROUND: Optical coherence tomography (OCT) is the main method for in vivo examination of morphology ocular posterior segment structures, used modern ophthalmological practice.
 AIM: Study special aspects performing and interpreting results OCT macula by ophthalmologists working healthcare system Russian Federation.
 MATERIALS AND METHODS: In anonymous survey, conducted using an original online questionnaire 12 questions 59 respondents took part. They confirmed being with...

10.17816/ov397388 article EN Ophthalmology Reports 2023-10-17

Intravitreal injection (IVI) is a drug delivery method, widely used in modern ophthalmology. To increase the awareness of patients receiving treatment healthcare system Russian Federation, Expert Council on Retinal and Optic Nerve Diseases Association Ophthalmologists, an All-Russian Public Organization 2020 proposed leaflet “Intravitreal injections (information for patients)”. Purpose: to conduct clinical assessment by multicenter anonymous surveying patients. Material methods. Patients who...

10.21516/2072-0076-2021-14-2-supplement-20-28 article EN cc-by Russian Ophthalmological Journal 2021-06-17

Patients lost to follow-up (LTFU) are a well-recognized challenge, both in clinical trials and real practice. PURPOSE: To study the reasons for patients receiving anti-VEGF therapy «wet¼ age-related macular degeneration (wAMD) environment cease monitoring clinic. MATERIAL AND METHODS: This retrospective cohort included with wAMD which received (ranibizumab, aflibercept) Ural State Medical University clinic from 2011 2019 (n=241). A subgroup of continuing treatment (n=90) was compared follow...

10.17116/oftalma202113702166 article EN Russian Annals of Ophthalmology 2021-01-01

Background.Anti-VEGF therapy is currently regarded as the gold standard for treatment of many macular diseases, while results its application in real clinical practice are often inferior to those from randomized trials.
 Materials and methods.A study group was formed on basis a retrospective analysis medical data patients who received anti-VEGF with ranibizumab and/or aflibercept according registered indications, discontinued their follow-up clinic (n= 214). A phone survey concerning...

10.17816/ov41716 article EN Ophthalmology Reports 2020-12-15

Purpose: to study long-term (over a 60 months’ follow-up period) results of anti-VEGF therapy for macular diseases in real clinical practice. Materials and methods . We undertook single-center retrospective uncontrolled cohort 169 patients (109 women, men) who received eye (ranibizumab, aflibercept). The treatment started between May 2010 August 2015. group included 57 remained under regular observation months. Of these, 24 cases had “wet” age-related degeneration (wAMD), 20 myopic choroidal...

10.21516/2072-0076-2022-15-3-11-17 article EN cc-by Russian Ophthalmological Journal 2022-09-22

Purpose: to study long-term results of anti-VEGF therapy for macular diseases patients followed up 60 months in real clinical practice. Materials and methods. The research group included 57 (43 women, 14 men; median age 62 years) who received antiVEGF (ranibizumab, aflibercept) remained under regular observation months. Of these, 24 had “wet” agerelated degeneration (wAMD), 20 myopic choroidal neovascularization (mCNV), 10 edema due retinal vein occlusions (MERVO), 3 diabetic (DME)....

10.21516/2072-0076-2022-15-4-7-17 article EN cc-by Russian Ophthalmological Journal 2022-12-14

Changes in choroidal thickness (CT) may indicate the presence of macular diseases and be used to monitor their course treatment. Automatic segmentation choroid is not currently available, semi-automatic laborious time-consuming. Purpose. To evaluate reproducibility CT manual measurement results using spectraldomain optical coherence tomography (SD-OCT) patients with pathological myopia. Material methods. A retrospective analysis SD-OCT (Optovue RTVue-100) data from macula myopic...

10.25276/2312-4911-2023-2-259-265 article EN Modern technologies in ophtalmology 2023-05-29

Introduction. The globalization influences the education system, and medical is not an exception. Along with general communication skills undergraduate students should demonstrate their competence in intercultural communication. aim of study was to implement elective course “Intercultural Communication” Russian school validate adapted questionnaire evaluate effectiveness teaching for development cultural awareness as a component competence. Materials Methods. developed implemented included...

10.32744/pse.2023.3.6 article EN Perspectives of science and education 2023-06-01

Relevance . Osteoporosis and chronic periodontitis are serious issues of modern life. The hypothesis that these two diseases associated is still open-ended doesn’t allow setting the record straight for lack sufficient evidence. Purpose study aimed to detect relationship between periodontal health parameters mineral bone density characteristics in postmenopausal women. Material methods examined 109 female patients with diagnosed moderate generalized (К05.31). participants formed groups: main...

10.33925/1683-3759-2023-751 article EN cc-by Parodontologiya 2023-11-28

Experimental results of remote laser measurement a time structure pulse wave are resulted. The executed measurements confirm the assumption that characteristics can be registered on basis Doppler's effect.

10.1109/dd.2012.6402756 article EN 2012-05-01

Chronic myocardial injury, determined by a constantly elevated cardiac troponin (cTn) value, may occur in patients with pulmonary arterial hypertension (PAH), indicating the severity of disease and associated an adverse prognosis. Increasing cTn among PAH was registered prior to 2018, but after Fourth universal definition infarction (2018) released understanding this phenomenon has been changed. One causes chronic injury is compression coronary arteries. Left main artery (LMCA) uncommon...

10.26442/2075082x.2018.4.180105 article EN cc-by Systemic Hypertension 2018-12-15

Aim. To evaluate the effectiveness of an original method cataract surgical treatment in patients with macular diseases receiving anti-VEGF therapy according to registered indications. Methods. A retrospective data analysis who received complex treatment, including ultrasound phacoemulsification combination intravitreal injections angiogenesis inhibitors (IVIAI; ranibizumab, aflibercept) before and after surgery prolonged anti-inflammatory (betamethasone into sub-Tenon's space), was carried...

10.25276/2686-6986-2021-2-15-19 article EN Reflection 2022-01-11

Purpose. To summarize the results of our own studies that examined various aspects patient adherence to anti-VEGF therapy in routine clinical practice. Material and methods.In a performed from 2014 2021, retrospective analysis data was carried out, as well survey patients with macular diseases (637 total, including neovascular age-related degeneration – 554 cases) who received (ranibizumab, aflibercept) for registered indications. Results. The influence on treatment factors established,...

10.25276/2312-4911-2022-1-278-283 article EN Modern technologies in ophtalmology 2022-03-25

Aim. In this article, we analyzed the age-related features of molecular- biological subtypes in 499 patients with invasive breast cancer. Materials and research methods. All cases were divided into 5 based on immunohistochemical studies hormone receptors, Her2, Ki-67. Luminal (A B) expression estrogen and/or progesterone receptors (ER+/PR+), accounting for about 50-80% all cancer potentially sensitive, especially luminal A, to therapy. Research results. The analysis showed that our study...

10.22138/2500-0918-2021-18-1-35-42 article EN cc-by-nc Journal of Ural Medical Academic Science 2021-01-01

Background . At present, intraocular drops of silicone oil, which is a lubricant for disposable syringes used intravitreal injections, are being actively studied. Among the undesirable effects their presence patient’s complaints visual discomfort associated with floating opacities, as well potential connection episodes inflammation and increased pressure. The aim : to assess prevalence oil droplets in vitreous patients treated multiple injections. Materials methods A single-center...

10.29413/abs.2021-6.5.12 article EN cc-by Acta Biomedica Scientifica (East Siberian Biomedical Journal) 2021-11-23
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