О. И. Лебедев

ORCID: 0000-0001-8190-4121
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About
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Research Areas
  • Glaucoma and retinal disorders
  • Retinal and Optic Conditions
  • Neurological Disorders and Treatments
  • Ocular Diseases and Behçet’s Syndrome
  • Cerebral Venous Sinus Thrombosis
  • Ocular Surface and Contact Lens
  • Ophthalmology and Eye Disorders
  • Corneal surgery and disorders
  • Sarcoidosis and Beryllium Toxicity Research
  • Medicinal plant effects and applications
  • Connexins and lens biology
  • Nail Diseases and Treatments
  • Ocular Oncology and Treatments
  • Circadian rhythm and melatonin
  • Traumatic Ocular and Foreign Body Injuries
  • Child and Adolescent Health
  • Acne and Rosacea Treatments and Effects
  • Infectious Diseases and Tuberculosis
  • Cutaneous Melanoma Detection and Management
  • Medical and Biological Sciences
  • Sinusitis and nasal conditions
  • Diverse Scientific Research in Ukraine
  • Peripheral Artery Disease Management
  • Retinal Diseases and Treatments
  • Ophthalmology and Visual Health Research

Budgetary Healthcare Institution of Omsk Region Regional Clinical Hospital
2025

Omsk State Medical University
2014-2024

Ministry of Health of the Russian Federation
2015-2016

This article presents the results of an international, multicenter, randomized, double-masked, placebo-controlled clinical study Visomitin (Mitotech LLC, Moscow, Russian Federation) eye drops in patients with dry syndrome (DES). is first registered (in Russia) drug a mitochondria-targeted antioxidant (SkQ1) as active ingredient. In this multicenter (10 sites) 240 subjects DES, (Visomitin or placebo) was self-administered three times daily (TID) for 6 weeks, followed by 6-week follow-up...

10.1007/s12325-015-0273-6 article EN cc-by-nc Advances in Therapy 2015-12-01

Abstract Background/Objectives To evaluate the efficacy and safety of preservative-free latanoprost eye drop emulsion in reducing intraocular pressure (IOP) versus preserved open-angle glaucoma (OAG) or ocular hypertension (OHT). Methods A Phase III non-inferiority study randomised patients with OAG/OHT 1:1 to receive latanoprost. The primary endpoint was change from baseline peak (9:00 A.M. ± 1 h) trough (4:00 P.M. IOP at Week 12 (non-inferiority margin: 95% confidence interval for...

10.1038/s41433-025-03646-z article EN cc-by Eye 2025-02-25

A retrospective study of 3346 clinical records patients with the diagnosis “Uveitis” (ICD-10 codes - H 20, 22, 30) hospitalized in “Clinical ophthalmologic hospital named after V. P. Vykhodtsev” Omsk from 2005 to 2012 was performed. The prevalence uveitis decreased by a factor 3.2 comparison measured 1995-2004 data. We also found statistically significant decrease incidence recurrent forms Compared time frame 1995-2004, immunoblot (West-ernblot) test use more frequently. comparative analysis...

10.17816/ov2014213-17 article EN Ophthalmology Reports 2014-06-15

BACKGROUND: A widespread visual impairment among medical students is known, but there are no data on the ophthalmic status of clinical residents. AIM: To carry out an assessment analyzer in Russian universities graduates who begin residency according to specialty 31.08.59 Ophthalmology. MATERIALS AND METHODS: An anonymous residents’ online survey was conducted 15 from 14 cities using original interactive questionnaire. Responses were received 249 respondents (mostly females: n = 188, 75.5%;...

10.17816/ov634872 article EN Ophthalmology Reports 2024-12-30

The functional or morphological changes associated with systemic diseases make up the bulk of eye pathology. Accordingly, drug therapy for these can affect eye. Changes organ vision and appropriate ophthalmological advice assist an internist to diagnose adequately treat patient. article considers possible in presence somatic diseases, as well alterations resulting from diseases.Существенную часть патологии глаза составляют функциональные или морфологические изменения, связанные с общими,...

10.17116/terarkh2015878132-136 article RU Terapevticheskii arkhiv 2015-01-01

The article presents three clinical cases of severe pathologies the anterior segment eye, which developed in patients with serious concomitant somatic diseases and COVID-19 under pandemic. Our observations show that SARS-CoV-2 virus can contribute to onset keratitis keratouveitis, characterized by a long torpid course, relapses, poorly predicted outcome. In coronavirus pathology, these have atypical symptoms complicate diagnosis, are resistant treatment, require an extended period...

10.21516/2072-0076-2022-15-2-supplement-129-137 article EN cc-by Russian Ophthalmological Journal 2022-06-16

The purpose: to evaluate the effectiveness of Delfanto® in complex therapy patients with dry eye syndrome various etiologies and severity clinical course. Patients methods . 114 (228 eyes) were examined: 72 chronic meibomian blepharitis dysfunction glands (xerosis due increased evaporation tear film), 33 women perimenopause (a mixed form xerosis a predominant decrease production components film) 9 persons Syegren pronounced production). All received individually selected replacement over...

10.18008/1816-5095-2020-3-481-489 article EN cc-by Ophthalmology in Russia 2020-09-24

PURPOSE : To study the distribution of intraocular pressure (IOP) obtained by Maklakov tonometry in different age groups. METHODS The evaluated Caucasians without glaucoma aged 45-75. participants underwent with a 10 g tonometer at 09:00-12:00 subsequent imprint evaluation means NesterovEgorov scale, measurements central corneal thickness (CCT) and visual acuity. All were divided into 3 groups age: Group 1 consisted 45-55, 2 comprised ones 56-65, included patients 66-75. RESULTS In total 791...

10.25700/njg.2020.02.05 article EN Национальный журнал глаукома 2020-10-09

Purpose. To study preliminary functional results in implantation of intrastromal corneal rings (MyoRing) the surgical treatment keratoconus. Material and methods. The focus group included 22 patients (22 eyes) with progressive keratoconus stage I-III according to Amsler classification, where MyoRings were implanted. mean follow-up w as 9 months. Results. uncorrected visual acuity (UCVA) after improved from 0.07Ѓ+0.05 0.47Ѓ+0.3 at end follow-up. There revealed significant differences values...

10.25276/0235-4160-2014-3-31-34 article EN Fyodorov journal of ophthalmic surgery 2015-10-12

To investigate parameters of intraocular fluid outflow after phacoemulsification cataract in patients with primary open-angle glaucoma (POAG).The study involved 153 (153 eyes), most whom also had POAG. The were divided into three groups: group 1 - 51 (51 eyes) but no glaucoma, 2 and early POAG, 3 advanced All them underwent non-contact pneumatic tonometry, tonography, tonography vacuum compression (Glau-Test60) before surgery (phacoemulsification implantation a posterior chamber lens (IOL))....

10.17116/oftalma2016132554-59 article RU Russian Annals of Ophthalmology 2016-01-01

This review provides information on the features, incidence, pathogenetic mechanism, possibilities of conservative, laser and surgical treatment glaucoma in pregnant women. The purpose this literature is to study features managing patients with during pregnancy. Glaucoma a large group eye diseases characterized by gradual development visual impairments atrophy optic nerve. pathology most common among population over 40 years old, but due advancement reproductive technologies, availability...

10.53432/2078-4104-2023-22-1-103-114 article EN cc-by National Journal glaucoma 2023-03-23
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