A5000162453- Glaucoma and retinal disorders
- Neurological Disorders and Treatments
- Corneal surgery and disorders
- Cerebral Venous Sinus Thrombosis
- Ocular Surface and Contact Lens
- Ophthalmology and Eye Disorders
- Flavonoids in Medical Research
- Retinal Diseases and Treatments
- Medicinal plant effects and applications
- Healthcare Systems and Public Health
- Technology and Human Factors in Education and Health
- Retinal and Optic Conditions
- Intraocular Surgery and Lenses
- Ocular Diseases and Behçet’s Syndrome
- Retinal Development and Disorders
- Retinal Imaging and Analysis
- Sympathectomy and Hyperhidrosis Treatments
- Corneal Surgery and Treatments
- Migraine and Headache Studies
- Neurological Disease Mechanisms and Treatments
- Redox biology and oxidative stress
- Chemical Reactions and Isotopes
- Ocular Disorders and Treatments
- Healthcare and Venom Research
- Facial Trauma and Fracture Management
Institute of the Human Brain
2021-2024
Samara Regional Clinical Hospital named after V.D. Seredavina
2021
Czech Academy of Sciences, Institute of Experimental Medicine
2019-2020
Academy of Medical Sciences
2020
Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences
2019
North-West Public Health Research Center
2017
Bashkir State Medical University
2002-2012
Purpose: to set out morphofunctional differences in the ophthalmic status between suspected glaucoma (SG) and initial stage of primary open angle (POAG), determine values interocular asymmetry analyzed parameters fellow eyes create a model able distinguish, with high accuracy, healthy subjects, SG patients POAG relying on few independent parameters. Material methods. A multicenter study performed July November, 2016, by 34 research clinical facilities four countries (Russia, Belarus,...
Коронавирусная инфекция может вызывать вирусный фолликулярный конъюнктивит. Однако пути передачи и тропность к клеткам конъюнктивы до сих пор остаются неизвестными. Возможность вовлечении в процесс заболевания глазной поверхности механизмы защиты глаз от вируса SARS-CoV-2.
Purpose . To study the influence of personal protective equipment (PPE) respiratory and visual systems on development progression dry eye syndrome (DES) its relationship with other risk factors for medical workers. Patients methods The data 243 people (male — 22.2 %, female 77.8 %) were analyzed as part a multi-center analytical scientific one-step study. Total tear production (Schirmer I test) was studied at beginning end working day in persons used PPE system (disposable face mask, gauze...
Despite the large amount of information, WHO-announced pandemic new coronavirus infection (COVID-19) remains poorly understood. Discussions are continuing about possibility transmission through eye, methods protecting medical personnel and patients, clinical manifestations, diagnosis, prevention treatment, organization ophthalmic care under epidemiological restrictions. The proposed literature review is an attempt to provide data on problem COVID-19 in ophthalmology.
PURPOSE: To determine individual clinical and epidemiological characteristics of the disease in patients with primary open-angle glaucoma (POAG) to establish its relationship adherence treatment. MATERIALS AND METHODS: The analytical, multicenter, combined study involved 1 092 subjects (2 184 eyes) different forms (general group) were selected using a survey, followed by their analysis. RESULTS: When verifying diagnosis, eyes POAG prevailed main group (from 89.6 92% all eyes). average age at...
PURPOSE. To determine individual clinical and epidemiological characteristics of the disease in patients with primary openangle glaucoma (POAG) to establish its relationship adherence treatment. METHODS. The analytical, multicenter, combined study involved 1 092 subjects (2 184 eyes) different forms (general group) were selected using a survey, followed by their analysis. RESULTS. When verifying diagnosis, eyes POAG prevailed main group (from 89.6 92% all eyes). average age at final...
Introduction. For the past several decades, there has been a discussion as to whether elevated intraocular pressure is just ocular hypertension in healthy eye, or sign of glaucoma. Objective. To study IOP values patients with primary open-angle glaucoma at beginning and correlated them disease progression determine optimal levels. Material methods. The final protocol included data from 812 right eyes 637 175 subjects; latter formed control group. mean age examined was 71.8 ± 0.28 years;...
To analyze the short-term efficacy and safety of Brolucizumab in treatment patients with neovascular age-related macular degeneration (nAMD).This retrospective pilot study included 154 (51 males 103 females, mean age 73.9±8.1 years). Among patients, 97 (63.0%) had previously been treated anti-VEGF drugs were this due to continuing disease activity. All underwent standard ophthalmological examination optical coherence tomography at initial visit as well each monthly visit.A total 283...
Purpose: To define the features of glaucoma progression, considering analysis treatment approaches (regimens) in patients with primary open-angle glaucoma. Methods: The multicenter clinical cohort study was performed during Nov 2015 - Jan 2018 30 bases 6 countries. Data 155 (247 eyes) included. Anamnesis, intraocular pressure (IOP) by moment first regimen as well administered were analyzed retrospectively. IOP (baseline and 5 more measurements each months) prospectively. During automated...
The review analyzes current literature data on the relationship between gender and glaucoma incidence, assesses demographic behavioral factors that may contribute to differences. Potential risks for development progression of in men women have been identified numerous studies, main ones being age, gender, race. prevalence world among people aged 40 80 years is higher than other age groups will grow steadily. Women are more likely suffer from closed-angle glaucoma, while primary open-angle...
Purpose — to analyze the literature data on benefits of preservative-free medication therapy for glaucoma. Materials and methods . 482 articles in Pubmed database published from 1975 2020 were analyzed using terms: “glaucoma”, “preservatives”, “preservative-free therapy”, “benzalkonium chloride”. The review includes 78 articles. Inclusion criteria: studies that examined effect local antihypertensive condition ocular surface comparison with drugs. Discussion BAC is most common preservative...
Modern multicenter studies of psychological features proper to glaucoma patients reveal the presence physiological and issues associated with condition. A high level anxiety causes a clinically significant increase intraocular pressure. The incidence depression in older people visual impairments is twice as general. Damaged field has an even more adverse effect on quality life than deterioration acuity, especially when defect localized lower hemisphere. failure comply prescribed...
Primary open-angle glaucoma (POAG) is a multifactorial, progressive disease, which pathogenesis not completely understood. This review analyzes studies that confirm the relationship between emotional state, mental characteristics, and morphological-functional state of central nervous system with development progression POAG. The psychopathological disorders are shown to be inevitable in such chronic neurodegenerative diseases as Alzheimer's disease glaucoma. article presents data confirming...
В статье обсуждаются возможности диагностики глаукомы с помощью глиальных биомаркеров. Клетки нейроглии играют ключевую роль в развитии нейровоспаления при глаукоме. Определение активности клеток сетчатки поможет выявлять специфические биомаркеры начинающегося глаукомного процесса. Среди биохимических маркеров активно исследуют нейроспецифические белки. Авторы анализируют имеющиеся данные о белках, используемых лабораторной диагностике. Протеин S100 – наиболее изученный и уже используемый...
Glaucoma is only partially associated with increased intraocular pressure. Normal-tension glaucoma (NTG) a form of open-angle in which optic nerve damage and visual field defects are present despite baseline pressure less than 21 mmHg. The exact mechanism by anatomical functional occurs remains unknown patients NTG. proposed theories, mechanical vascular, do not fully explain the pathogenesis disease. This dictates need to perform both structural ophthalmological radiological diagnostic...
Review of herbal remedies in alternative antihypertensive and neuroprotective treatment glaucoma Due to the fact that is a chronic, slowly progressive disease, patients are often disappointed traditional methods, this leads an independent search for other strategies. The purpose review summarize data on effect agents course glaucomatous process discuss validity their use. An analysis works devoted study hypotensive effects medicine was carried out. results presented allow us conclude tactics...
PURPOSE: To determine the effect of some IOP level indicators on disease progression in patients with primary open-angle glaucoma. METHODS: This combined, analytical scientific and clinical multicenter cohort study was conducted between January April 2017. A total 136 participants (237 eyes) from 30 academic referral centers 6 (six) countries (Belarus, Kazakhstan, Kyrgyzstan, Moldova, Russia, Uzbekistan) were enrolled — 52 (38.2%) males 84 (61.8%) females. As a first step, glaucoma...
Today, glaucoma is considered to be the most common cause of irreversible blindness. The treatment this disease aimed at reducing intraocular tension in order slow down deterioration visual functions and maintain accept‑ able quality life. Most ophthalmologists prefer local medicamentous therapy. Despite a significant expansion range antihypertensive medicines, increase hypotensive effect not always achieved each certain case, same time, long-term (sometimes lifetime) systemic adverse...
Objective: to determine the efficiency of treatment for glaucoma and its accompanying costs in patients with II-III stages open-angle glaucoma. Material methods. The multicenter study which was conducted by 35 investigators 29 clinical centers 4 CIS countries from December 2013 April 2014 took into account results 115 (187 eyes) cost «cost-effectiveness» intraocular pressure (IOP)-lowering were calculated IOP-level compensation. Results. average cost-effectiveness 13.94 ± 0.66 rubles/day,...
The novel coronavirus infection (COVID-19) provides powerful effects on all pathogenic aspects of the primary open-angle glaucoma (POAG). property this virus to initiate disseminated intravascular coagulation, damage endotheliocytes, and impair coagulation result in numerous severe complications affecting organs systems. This disorder provokes retinal ischemia hypoxia spurs apoptosis ganglionic cells. Cytokine storm oxidative stress resulting from COVID-19 potentially contribute progression...
Today glaucoma is the leading cause of irreversible blindness. Intraocular pressure level only directly influenced factor which can stop visual function deterioration and prevent loss. Generally, IOP reduction starts with topical therapy, adversely affect ocular surface impair prognosis possible future surgery. Long-term medical therapy leads to changes induces chronic inflammation, promotes scarring newly created outflow pathways. This in turn may hinder ultimately block from anterior...