A. Yu. Brezhnev

ORCID: 0000-0002-5597-983X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Glaucoma and retinal disorders
  • Neurological Disorders and Treatments
  • Cerebral Venous Sinus Thrombosis
  • Corneal surgery and disorders
  • Ocular Surface and Contact Lens
  • Ophthalmology and Eye Disorders
  • Retinal Diseases and Treatments
  • Retinal Imaging and Analysis
  • Migraine and Headache Studies
  • Retinal and Optic Conditions
  • Medicinal plant effects and applications
  • Glutathione Transferases and Polymorphisms
  • Healthcare Systems and Public Health
  • Ocular Diseases and Behçet’s Syndrome
  • Multiple Sclerosis Research Studies
  • Cardiovascular Health and Disease Prevention
  • Flavonoids in Medical Research
  • Peripheral Neuropathies and Disorders
  • Urticaria and Related Conditions
  • Cholinesterase and Neurodegenerative Diseases
  • Economic Development and Digital Transformation
  • Pharmacology and Obesity Treatment
  • Food Industry and Aquatic Biology
  • Retinal Development and Disorders
  • Infection Control and Ventilation

Kursk State Medical University
2015-2024

Ministry of Health of the Russian Federation
2022

Currently, the level of intraocular pressure (IOP) can be assessed with a large number tonometers, which differ in principle action, place application and degree invasiveness. All methods use - except for direct manometry allow only indirect judgement ophthalmotonus. The quality tonometric measurement is influenced by many factors, from choice tonometer to analysis results obtained doctor. complex assessing provides additional information that increases its diagnostic value. This article...

10.17116/oftalma2020136061100 article RU Russian Annals of Ophthalmology 2020-01-01

Purpose: to set out morphofunctional differences in the ophthalmic status between suspected glaucoma (SG) and initial stage of primary open angle (POAG), determine values interocular asymmetry analyzed parameters fellow eyes create a model able distinguish, with high accuracy, healthy subjects, SG patients POAG relying on few independent parameters. Material methods. A multicenter study performed July November, 2016, by 34 research clinical facilities four countries (Russia, Belarus,...

10.21516/2072-0076-2017-10-4-5-15 article EN cc-by Russian Ophthalmological Journal 2017-01-01

Purpose . To study the influence of personal protective equipment (PPE) respiratory and visual systems on development progression dry eye syndrome (DES) its relationship with other risk factors for medical workers. Patients methods The data 243 people (male — 22.2 %, female 77.8 %) were analyzed as part a multi-center analytical scientific one-step study. Total tear production (Schirmer I test) was studied at beginning end working day in persons used PPE system (disposable face mask, gauze...

10.18008/1816-5095-2020-3-519-526 article EN cc-by Ophthalmology in Russia 2020-09-24

PURPOSE: To determine individual clinical and epidemiological characteristics of the disease in patients with primary open-angle glaucoma (POAG) to establish its relationship adherence treatment. MATERIALS AND METHODS: The analytical, multicenter, combined study involved 1 092 subjects (2 184 eyes) different forms (general group) were selected using a survey, followed by their analysis. RESULTS: When verifying diagnosis, eyes POAG prevailed main group (from 89.6 92% all eyes). average age at...

10.25700/njg.2021.01.01 article EN 2021-03-23

PURPOSE. To determine individual clinical and epidemiological characteristics of the disease in patients with primary openangle glaucoma (POAG) to establish its relationship adherence treatment. METHODS. The analytical, multicenter, combined study involved 1 092 subjects (2 184 eyes) different forms (general group) were selected using a survey, followed by their analysis. RESULTS. When verifying diagnosis, eyes POAG prevailed main group (from 89.6 92% all eyes). average age at final...

10.53432/2078-4104-2021-20-2-31-42 article EN cc-by National Journal glaucoma 2021-07-11

Introduction. For the past several decades, there has been a discussion as to whether elevated intraocular pressure is just ocular hypertension in healthy eye, or sign of glaucoma. Objective. To study IOP values patients with primary open-angle glaucoma at beginning and correlated them disease progression determine optimal levels. Material methods. The final protocol included data from 812 right eyes 637 175 subjects; latter formed control group. mean age examined was 71.8 ± 0.28 years;...

10.17816/ov2015143-60 article EN Ophthalmology Reports 2015-03-15

Purpose: To define the features of glaucoma progression, considering analysis treatment approaches (regimens) in patients with primary open-angle glaucoma. Methods: The multicenter clinical cohort study was performed during Nov 2015 - Jan 2018 30 bases 6 countries. Data 155 (247 eyes) included. Anamnesis, intraocular pressure (IOP) by moment first regimen as well administered were analyzed retrospectively. IOP (baseline and 5 more measurements each months) prospectively. During automated...

10.25700/njg.2019.01.07 article EN Национальный журнал глаукома 2019-05-14

The review analyzes current literature data on the relationship between gender and glaucoma incidence, assesses demographic behavioral factors that may contribute to differences. Potential risks for development progression of in men women have been identified numerous studies, main ones being age, gender, race. prevalence world among people aged 40 80 years is higher than other age groups will grow steadily. Women are more likely suffer from closed-angle glaucoma, while primary open-angle...

10.21516/2072-0076-2021-14-3-120-123 article EN cc-by Russian Ophthalmological Journal 2021-09-15

Purpose — to analyze the literature data on benefits of preservative-free medication therapy for glaucoma. Materials and methods . 482 articles in Pubmed database published from 1975 2020 were analyzed using terms: “glaucoma”, “preservatives”, “preservative-free therapy”, “benzalkonium chloride”. The review includes 78 articles. Inclusion criteria: studies that examined effect local antihypertensive condition ocular surface comparison with drugs. Discussion BAC is most common preservative...

10.18008/1816-5095-2021-3-532-538 article EN cc-by Ophthalmology in Russia 2021-10-01

The “classical” scheme of prescribing regimens to patients with newly diagnosed primary open-angle glaucoma (POAG) implies initial monotherapy treatment, which is practiced in any stage the disease. This turn a consistent strengthening regimes. Thus, “modern” clinical algorithm practically excludes possibility treatment combined medicines, laser or conventional surgery. At same time, differentiated («stepwise») approache used other disciplines makes it possible achieve control over disease...

10.25700/njg.2018.04.03 article EN 2018-12-27

10.21689/2311-7729-2016-16-4-214-219 article EN Russian Journal of Clinical Ophthalmology 2016-01-01

PURPOSE . To study the opinion of ophthalmologists about usefulness training programs presented on continuing medical education (CME) web portal, their significance and impact process obtaining knowledge in modern conditions, when scene is dominated by hybrid forms education. MATERIAL AND METHODS This was multicenter scientific analytical selective cross-sectional observational design conducted period from June to September 2021; it based data obtained an online survey among Russian with...

10.53432/2078-4104-2022-21-1-62-70 article EN cc-by National Journal glaucoma 2022-03-14

The analysis of trends in the surgical treatment primary open-angle glaucoma (POAG) allows assessing changes indications for treatment, number surgery and their modifications, as well demographic characteristics patients, duration preoperative therapy effectiveness treatment. results indicate that over past 20 years Russian Federation there was a shift towards an increasingly long-term therapeutic strategy used before stage and, general, decrease performed surgeries. There is much concern...

10.53432/2078-4104-2024-23-1-75-87 article EN National Journal glaucoma 2024-04-26

Studies in recent years have shown an increase the prevalence of systemic diseases, some which may be independent risk factors for development and progression glaucoma. Metabolic syndrome (MetS) is currently one leading public health problems world. Some studies indicate a relationship between MetS its individual components (in particular, insulin resistance, hyperglycemia, impaired homeostasis, arterial hypertension) with intraocular pressure (IOP), ocular hypertension, primary open-angle...

10.53432/2078-4104-2024-23-2-107-116 article EN National Journal glaucoma 2024-06-27

Актуальность. Ряд исследований указывают на возможную взаимосвязь метаболического синдрома (МС) и его отдельных компонентов с повышенным риском развития первичной открытоугольной глаукомы (ПОУГ). Цель. Изучить распространенность дислипидемии у пациентов ПОУГ фоне МС. Материал методы. Обследовано 211 в возрасте 66,7±4,5 лет. Всем пациентам проведены стандартные офтальмологические лабораторные исследования: липидограмма определением холестерина (ХС), липопротеидов низкой плотности (ЛПНП),...

10.25276/2312-4911-2024-4-92 article RU Modern technologies in ophtalmology 2024-06-15

PURPOSE. To study the clinical and demographic characteristics of patients with end-stage primary open-angle glaucoma (POAG). METHODS. The included 159 (318 eyes) a median age 72.2 years (64.7; 79.7), POAG in one eye. All underwent comprehensive ophthalmologic examination, thorough review medical history records. Data were processed by single investigator subsequent selective verification. RESULTS. More than 50 analyzed, focusing on four key factors: age, duration follow-up, stage at time...

10.53432/2078-4104-2024-23-3-3-13 article EN National Journal glaucoma 2024-09-19

PURPOSE:  To determine the effect of some IOP level indicators on disease progression in patients with primary open-angle glaucoma. METHODS:  This combined, analytical scientific and clinical multicenter cohort study was conducted between January April 2017. A total 136 participants (237 eyes) from 30 academic referral centers 6 (six) countries (Belarus, Kazakhstan, Kyrgyzstan, Moldova, Russia, Uzbekistan) were enrolled — 52 (38.2%) males 84 (61.8%) females. As a first step, glaucoma...

10.25700/njg.2018.01.02 article EN Национальный журнал глаукома 2018-04-04

A study of cross-impact degree and morpho-functional correlation characteristics primary open angle glaucoma age-related macular degeneration was performed at 25 clinical sites in Russia some CIS countries from January through May 2013. The final protocol included 87 patients (108 eyes) divided into two groups, mean age 66.6 ± 5.65 years (min 55; max 81). Intragroup intergroup variance analysis did not establish any significant difference the area between «glaucoma» group «glaucoma + AMD»...

10.17816/ov2014119-27 article EN Ophthalmology Reports 2014-03-15

Objective: to determine the efficiency of treatment for glaucoma and its accompanying costs in patients with II-III stages open-angle glaucoma. Material methods. The multicenter study which was conducted by 35 investigators 29 clinical centers 4 CIS countries from December 2013 April 2014 took into account results 115 (187 eyes) cost «cost-effectiveness» intraocular pressure (IOP)-lowering were calculated IOP-level compensation. Results. average cost-effectiveness 13.94 ± 0.66 rubles/day,...

10.51523/2708-6011.2015-12-1-6 article EN cc-by-nc-nd Health and Ecology Issues 2015-03-28

Aim: to assess the changes in clinical and epidemiological characteristics, diagnostic treatment options of primary open-angle glaucoma (POAG) Russian Federation multiple near- far-abroad countries over period 2005–2020. Patients Methods: final protocol this retrospective multi-center research study included 289 patients with POAG from 7 states (Russia, Belarus, Serbia, Moldova, Kyrgyzstan, Slovakia, Slovenia). The authors analyzed methods used for establishing POAP diagnosis, demographic...

10.32364/2311-7729-2023-23-2-73-79 article EN cc-by Russian Journal of Clinical Ophthalmology 2023-01-01

The prevalence of multimorbidity defined as the presence two or more chronic diseases increases with ageing. Multimorbidity which is associated a decline in quality life and functional abilities results increase rate various physiological disorders hospital treatment and, therefore, growing healthcare costs. Glaucoma treatment, particular, elderly patients, often accompanied by systemic comorbidities intake multiple drugs. Some agents are known to affect development glaucoma (i.e.,...

10.32364/2311-7729-2020-20-4-191-196 article EN cc-by Russian Journal of Clinical Ophthalmology 2020-01-01
Coming Soon ...