A5107274278- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Intraocular Surgery and Lenses
- Ocular Surface and Contact Lens
- Ophthalmology and Visual Impairment Studies
- Corneal Surgery and Treatments
- Retinal and Optic Conditions
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Macular Surgery
- Optical Coherence Tomography Applications
- Multiple Sclerosis Research Studies
- Systemic Lupus Erythematosus Research
- Retinal Development and Disorders
- Ocular Infections and Treatments
- Medical and Biological Ozone Research
- Bipolar Disorder and Treatment
- Antibiotics Pharmacokinetics and Efficacy
- Renal Diseases and Glomerulopathies
- Wound Healing and Treatments
- Protein Interaction Studies and Fluorescence Analysis
- Musculoskeletal pain and rehabilitation
- Animal testing and alternatives
- Phenothiazines and Benzothiazines Synthesis and Activities
Hospital Universitario Miguel Servet
2014-2025
Universidad de Zaragoza
2010-2025
Instituto de Investigación Sanitaria Aragón
2010-2024
Instituto Aragonés de Ciencias de la Salud
2007-2014
Servicio Aragonés de Salud
2013
Purpose: To evaluate the ability of new Swept source (SS) optical coherence tomography (OCT) technology to detect changes in retinal and choroidal thickness patients with Parkinson's disease (PD).Design: Observational case–control cross sectional study, developed from January May 2016.Methods: In total, 50 eyes diagnosed PD 54 healthy controls underwent assessment using SS DRI Triton OCT (Topcon), 3D Wide protocol. Total macular peripapillary data (retinal, ganglion cell layer [GCL+, GCL++]...
The optical quality of a set IOLs (modeling set: one monofocal and two bifocals) was assessed through focus by the area under modulation transfer function (MTFa) metric related to visual acuity (VA) defocus curves pseudophakic patients implanted with said IOLs. A non-linear relationship between MTFa clinical VA obtained an asymptotic limit found be best achievable patients. Two mathematical fitting functions were derived high correlation coefficients (R2≥0.85). They applied from different...
Purpose: To evaluate visual and retinal changes in patients with bipolar disorder. analyze the correlation between structural function parameters. Methods: Thirty disorder 80 healthy controls underwent evaluation Early Treatment Diabetic Retinopathy Study charts at 100%, 2.50%, 1.25% contrast, Pelli-Robson chart, color vision Farnsworth Lanthony tests. Analysis of different layers was performed using Spectralis optical coherence tomography automated segmentation software. Correlation...
Purpose To investigate superficial retinal microvascular plexuses detected by optical coherence tomography angiography (OCT-A) in multiple sclerosis (MS) subjects and compare them with healthy controls. Methods A total of 92 eyes from patients relapsing-remitting MS 149 control were included this prospective observational study. OCT-A imaging was performed using Triton Swept-Source OCT (Topcon Corporation, Japan). The vessel density (VD) percentage the plexus optic disc area (6 x 6 mm grid)...
Abstract Background/Objectives To evaluate the efficacy and safety of preservative-free latanoprost eye drop emulsion in reducing intraocular pressure (IOP) versus preserved open-angle glaucoma (OAG) or ocular hypertension (OHT). Methods A Phase III non-inferiority study randomised patients with OAG/OHT 1:1 to receive latanoprost. The primary endpoint was change from baseline peak (9:00 A.M. ± 1 h) trough (4:00 P.M. IOP at Week 12 (non-inferiority margin: 95% confidence interval for...
To compare visual quality in patients implanted with Tecnis® monofocal (ZCB00) and multifocal (ZMB00) intraocular lenses taking into account their optical measured vitro an eye model.In total, 122 participated this study: 44 78 lenses. Measurements of acuity contrast sensitivity were performed. The the was evaluated three image planes (distance, intermediate near) using model on a test bench. metric considered area under curve modulation transfer function.Optical at far focus lens (area...
To study peripapillary choroidal thickness (PPCT) around the optic disc and establish zones using a new swept source optical coherence tomography (SS-OCT) device. evaluate PPCT differences between patients with multiple sclerosis (MS) age- sex-matched healthy controls.A total of 102 subjects 51 MS were consecutively recruited. Healthy divided into teaching (n = 51, used to zones) validating compare measurements patients) populations. An 6.0 × 6.0-mm three-dimensional scan was obtained SS-OCT...
Purpose To compare the NEI-RQL-42 quality of life questionnaire and Radner Vissum reading test outcomes after bilateral cataract surgery with implantation Tecnis ZCB00 monofocal ZMB00 multifocal intraocular lens (IOL). Methods Forty-two eyes 21 patients who had phacoemulsification were implanted IOL 82 41 IOL. They answered before 3 months it. The was performed optical correction for near vision in IOL, but without it Results Regarding test, group obtained better results items 2, 7, 8, 11,...
Purpose . To evaluate the ability of new swept-source (SS) optical coherence tomography (OCT) technology to detect changes in retinal and choroidal thickness patients with multiple sclerosis (MS). Methods A total 101 healthy 97 MS eyes underwent assessment using SS Triton OCT (Topcon). Macular peripapillary data (retinal, ganglion cell layer (GCL+, GCL++) nerve fiber (RNFL) thickness) were analyzed, including evaluation. Results Significant macular thinning was observed all ETDRS areas...
Purpose: To compare toric intraocular lens (TIOL) implantation and femtosecond laser–assisted arcuate keratotomy (FSAK) during phacoemulsification surgery in correction of moderate astigmatism. Setting: Clinical research study. Design: Prospective randomized comparison Methods: Patients with age-related cataract preoperative corneal astigmatism 1.25 to 3.0 diopters (D) were into a TIOL group an FSAK symmetrical paired keratotomies. The evaluation included corrected distance visual acuity...
To evaluate the reproducibility of repeated quantitative measurements optic nerve head topography and retinal fiber layer thickness.This study included 32 normal subjects, 41 patients with ocular hypertension 33 glaucoma. The groups were defined by intraocular pressure levels, disc stereo-photographs perimetric performance. Optic assessments performed coherence tomography (OCT III, Zeiss Instruments). OCT examination was three times in each subject coefficient variability elaborated for...
<b><i>Purpose:</i></b> The purpose of this study is to describe a case ocular rosacea with very complex evolution. Rosacea chronic dermatological disease that may affect the structures up 6-72% all cases. This form often misdiagnosed, which lead long inflammatory processes important visual consequences for affected patients. Therefore, an early diagnosis and adequate treatment are important. <b><i>Methods:</i></b> We report 43-year-old patient...
To evaluate and compare peripapillary choroidal thickness (PPCT) in a wide area around the optic disk various established zones healthy controls primary open-angle glaucoma (POAG) patients using new swept-source (SS) optical coherence tomography (OCT) device.A total of 246 eyes were finally included this observational, prospective, cross-sectional study: 111 135 POAG patients. The subjects divided into 2 populations: teaching population (25 used to establish zones) validating (86 for...
Objetivo: Determinar las correlaciones entre los parámetros estructurales de la cabeza del nervio óptico y CFNR obtenidos mediante topografía papilar (HRT II), tomografía óptica coherencia (Stratus OCT 3000) polarimetría láser (GDx VCC), con índices globales perimetría automatizada convencional en sujetos normales, hipertensos oculares glaucoma.Material método: Trescientos ochenta nueve ojos fueron incluidos el estudio clasificados 3 grupos: 43 274 72 glaucomas según resultados presión...
Objective To assess changes in the retinal nerve fiber layer (RNFL) and macula subjects with cardiovascular risk factors or subclinical ischemia. Design Prospective observational study. Methods A total of 152 healthy men underwent examination, including quantification atheroma plaques by artery ultrasound scans, blood analysis, a complete ophthalmic evaluation, spectral-domain optical coherence tomography. The variables registered examination were classic major factors, analytical records....
To evaluate the inner retinal layers in fibromyalgia (FM) patients compared to control subjects using posterior pole protocol (PPole) analysis optical coherence tomography (OCT) and correlate structural changes with subjective quality of life.Seventy-four eyes healthy 55 those FM were analyzed. All underwent evaluation PPole for Spectralis OCT (Heidelberg Engineering) obtain measurements nerve fiber layer (RNFL) ganglion cell (GCL) macular area. The EuroQol (EQ-5D) questionnaire Fibromyalgia...
Purpose To assess the ability of a new posterior pole protocol to detect areas with significant differences in retinal nerve fiber layer (RNFL) and ganglion cell (GCL) thickness patients multiple sclerosis versus healthy control subjects; addition, correlation between RNFL GCL thickness, disease duration, Expanded Disability Status Scale (EDSS). Methods We analyzed 66 eyes subjects 100 remitting-relapsing (RR-MS) patients. Double analysis based on first clinical symptom onset (CSO)...
Objective: To compare retinal nerve fiber layer (RNFL) measurements performed with Stratus OCT 3000 in normal, ocular hypertensive, pre-perimetric and glaucomatous eyes.Methods: 98 normal subjects, 156 hypertensives short-wavelength automated perimetry (SWAP), 21 altered SWAP (pre-perimetric glaucoma) 66 eyes were included the study.Diagnostic groups classified based on intraocular pressure, optic head appearance, achromatic automatic SWAP.RNFL parameters obtained using a (Humphrey Zeiss...