A5036443714- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Retinal and Macular Surgery
- Ocular Diseases and Behçet’s Syndrome
- Intraocular Surgery and Lenses
- Retinal Development and Disorders
- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Ocular and Laser Science Research
- Ocular Infections and Treatments
- Cerebral Venous Sinus Thrombosis
- Retinopathy of Prematurity Studies
- Vascular Malformations Diagnosis and Treatment
- Ocular Surface and Contact Lens
- Systemic Lupus Erythematosus Research
- Health Systems, Economic Evaluations, Quality of Life
- Drug-Induced Ocular Toxicity
- Neurological Complications and Syndromes
- Ophthalmology and Visual Health Research
- Traumatic Ocular and Foreign Body Injuries
- Optical Coherence Tomography Applications
- Acute Ischemic Stroke Management
- Ocular Disorders and Treatments
University of Udine
2016-2025
Istituto Europeo di Microchirurgia Oculare
2016-2025
University College London
2023
Tianjin Medical University Eye Hospital
2023
Moorfields Eye Hospital
2023
Tianjin Medical University
2023
Singapore National Eye Center
2023
Inserm
2023
Université de Bordeaux
2023
Vita-Salute San Raffaele University
2021
ObjectiveTo evaluate long-term efficacy and safety profiles during 3 years of individualized ranibizumab treatment in patients with visual impairment due to diabetic macular edema (DME).DesignPhase IIIb, multicenter, 12-month, randomized core study 24-month open-label extension study.ParticipantsOf the 303 who completed RESTORE 12-month study, 240 entered study.MethodsIn were eligible receive as month 12 guided by best-corrected acuity (BCVA) disease progression criteria at investigators'...
<h3>Background:</h3> Neovascular age-related macular degeneration (AMD) has a poor prognosis if left untreated, frequently resulting in legal blindness. Ranibizumab is approved for treating neovascular AMD. However, further guidance needed to assist ophthalmologists clinical practice optimise treatment outcomes. <h3>Methods:</h3> An international retina expert panel assessed evidence available from prospective, multicentre studies evaluating different ranibizumab schedules (ANCHOR, MARINA,...
Retinal vein occlusion (RVO) can have severe consequences for the people affected by disease, including visual loss with costly social repercussions. Currently, there is no European consensus regard to management of RVO. Following a careful review medical literature as well data from several clinical trials, collaborative group retina specialists put forth practical recommendations based on best available scientific evidence approach Taking into consideration recent advances in diagnostic...
To evaluate the efficacy and safety of ranibizumab 0.5 mg in adult patients with choroidal neovascularization because an uncommon cause enrolled 12-month MINERVA study.In this Phase III, double-masked study, (≥18 years) (N = 178) were randomized 2:1 to receive either (n 119) or sham 59) at baseline and, if needed, Month 1 open-label individualized from 2. Best-corrected visual acuity change 2 (primary endpoint) 12, treatment exposure, over 12 months reported. Subgroup analysis was conducted...
To present an authoritative, universal, easy-to-use morphologic classification of diabetic maculopathy based on spectral domain optical coherence tomography.The first draft the project was developed previously published classifications and a literature search regarding tomography quantitative qualitative features maculopathy. This sent to international panel retina experts for revision. The met at European School Advanced Studies in Ophthalmology headquarters Lugano, Switzerland, elaborated...
To verify the efficacy of nonvisible micropulse diode laser irradiation in treatment central serous chorioretinopathy (CSC).Twenty-two patients with CSC for a total 24 eyes disease duration longer than 3 months were included prospective study. Patients underwent Early Treatment Diabetic Retinopathy Study visual acuity (VA) examination, dilated ophthalmoscopy, fluorescein angiography, and optical coherence tomography before during follow- up. was given duty cycle 15%. Multiple spots placed...
Purpose.: To evaluate the psychometric characteristics of National Eye Institute Visual Function Questionnaire-25 (NEI VFQ-25) in patients with age-related macular degeneration (AMD) who participated two clinical trials. Methods.: A secondary analysis data from randomized trials was performed. NEI VFQ-25 were collected 1134 1146 subfoveal choroidal neovascularization due to AMD minimally classic or occult no types and predominantly type. The administered at baseline months 1, 2, 3, 6, 9, 12,...
Purpose To evaluate the real-life safety profile of intravitreal dexamethasone implant injection for various retinal conditions. Methods Retrospective multicenter analysis injections (700 µg) due to conditions including central venous occlusion (1861 injections), diabetic macular oedema (3104 post-surgical cystoid (305 injections) and uveitis (381 injections). The eyes were evaluated mainly occurrence adverse events such as glaucoma, cataract, detachment endophthalmitis along during...
Dexamethasone intravitreal implant 0.7 mg (DEX 0.7) was approved for treatment of diabetic macular edema (DME) after demonstration its efficacy and safety in the MEAD registration trials. We performed subgroup analysis study results to evaluate DEX patients with previously treated DME. Three-year, randomized, sham-controlled phase 3 DME, best-corrected visual acuity (BCVA) 34–68 Early Treatment Diabetic Retinopathy Study letters (20/200–20/50 Snellen equivalent), central retinal thickness...
To compare the number of eye surgical procedures performed in Italy 2 months following beginning lockdown (study period) because COVID-19 epidemic with those two earlier same year (intra-year control) and period 2019 corresponding to (inter-year control).Retrospective analysis carried out at 39 Academic hospitals. A distinction was made between elective urgent procedures. Intravitreal injections were also considered. Percentages for all incidence rate ratios (IRR) rhegmatogenous retinal...