A5038413562- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Ocular Oncology and Treatments
- Retinal and Optic Conditions
- Retinal Development and Disorders
- Corneal Surgery and Treatments
- Corneal surgery and disorders
- Retinal and Macular Surgery
- Ocular Surface and Contact Lens
- Nonmelanoma Skin Cancer Studies
- Cutaneous Melanoma Detection and Management
- Intraocular Surgery and Lenses
- Cancer and Skin Lesions
- Neurofibromatosis and Schwannoma Cases
- Ocular Infections and Treatments
- Ophthalmology and Visual Impairment Studies
- Vascular Malformations Diagnosis and Treatment
- Ocular Diseases and Behçet’s Syndrome
- melanin and skin pigmentation
- Meningioma and schwannoma management
- Ocular and Laser Science Research
- Glioma Diagnosis and Treatment
- Retinopathy of Prematurity Studies
- Immunotherapy and Immune Responses
University of Padua
2016-2025
Fondazione G.B. Bietti
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2025
Chartered Institute of Architectural Technologists
2024
Azienda Ospedaliera di Padova
2022
Vilnius University
2021
University College London
2021
Masaryk University
2021
N.N. Alexandrov National Cancer Centre
2021
Children's Clinical University Hospital
2021
To evaluate the changes in thickness of individual inner and outer macular peripapillary retinal layers diabetes. 124 subjects (124 eyes) were enrolled: 74 diabetics 50 controls. Macular edema, proliferative diabetic retinopathy (DR), any intraocular treatment refractive error >6 diopters main exclusion criteria. Full ophthalmic examination, stereoscopic fundus photography, spectral domain-OCT performed. After automatic segmentation (layering) 5 layers, each layer was calculated, values...
The high prevalence of cardiovascular disease particularly in the elderly population is associated with retinal vascular disease. Retinal vein occlusions represent severe disturbances hypoxia-sensitive neurosensory retina. Acute and excessive leakage leads to diagnostic hallmarks hemorrhage edema substantial thickening. Advanced tools such as OCT angiography allow evaluate ischemia identify risk for late complications will soon reach clinical routine besides fluorescein angiography....
Early age-related macular degeneration (AMD) has been correlated with different functional alterations, but the exact relationship between fundus lesions and overlying sensitivity is not well known. The aim of this study was to compare fundus-related (microperimetry) autofluorescence (FAF) area drusen pigment abnormalities in early AMD.13 consecutive patients AMD visual acuity 20/20 were studied by means microperimetry, which automatically analyses light differential threshold fixation...
To investigate macular and peripapillary choroidal thickness (CT) in diabetic patients with without retinopathy (DR).One hundred fifty subjects were enrolled: 102 (102 eyes) 48 normals, as controls. Exclusion criteria previously treated DR, refractive error higher than ± 3 diopters, or untreated glaucoma. All underwent full ophthalmic examination, stereoscopic color fundus photography, spectral domain optical coherence tomography (RS-3000; Nidek). Spectral examination consisted of linear...
The purpose of this study was to evaluate and compare microperimetry fundus autofluorescence (FAF) after subthreshold micropulse diode laser versus modified Early Treatment Diabetic Retinopathy Study photocoagulation for clinically significant diabetic macular edema.A prospective randomized clinical trial including 62 eyes (50 patients) with untreated, center-involving, edema performed. All patients underwent best-corrected visual acuity determination (logarithm the minimum angle...
PURPOSE.To compare the changes in macular sensitivity (microperimetry) and thickness with different degrees of diabetic edema.METHODS.Sixty-one eyes 32 consecutive patients were included this cross-sectional study.All underwent functional morphologic examination area.Best corrected visual acuity (ETDRS charts), sensitivity, quantified.Lesion-related retinal fixation investigated an advanced, automatic microperimeter.Optical coherence tomography (OCT) was used to quantify...
Purpose . To evaluate the presence of hyperreflective spots (HRS) in diabetic patients without clinically detectable retinopathy (no DR) or with nonproliferative mild to moderate (DR) macular edema, and compare results controls. Methods 36 subjects were enrolled: 12 no DR, normal who served as All studied underwent full ophthalmologic examination spectral domain optical coherence tomography (SD-OCT). SD-OCT images analyzed measure localize HRS. Each image was by two independent, masked...
This cross-sectional study evaluated the relationship between 1) functional and structural measurements of neurodegeneration in initial stages diabetic retinopathy (DR) 2) presence early microvascular impairment. We analyzed baseline data 449 patients with type 2 diabetes enrolled European Consortium for Early Treatment Diabetic Retinopathy (EUROCONDOR) (NCT01726075). Functional studies by multifocal electroretinography (mfERG) neurodysfunction, using spectral domain optical coherence...
Abstract Purpose To evaluate changes of specific retinal imaging biomarkers [intraretinal hyper‐reflective spots: HRS ; subfoveal neuroretinal detachment: SND and increased foveal autofluorescence: IFAF after intravitreal steroid or anti‐vascular endothelial growth factor treatment in diabetic macular oedema ( DME )] as possible indicators inflammatory condition. Methods Retrospective analysis images clinical charts 49 eyes (49 patients) with treated dexamethasone (dexamethasone, 23 eyes)...
To evaluate hyperreflective retinal spots (HRS), in normal subjects and diabetic patients without with macular edema (diabetic edema, DME), on linear B-scans corresponding en face image of spectral-domain optical coherence tomography.Retrospective evaluation images 54 eyes/subjects (16 subjects, 19 DME, DME). On horizontal B-scan tomography, passing through the center fovea, following characteristics HRS were evaluated: location (inner retina or outer retina), size (≤30 >30 μm), reflectivity...
To evaluate and compare in vivo retinal choroidal morphologic changes macular function patients treated with yellow (Y-MPL) or infrared (IR-MPL) subthreshold micropulse laser center-involving diabetic edema.Prospective, randomized, single institution, comparative 6-month pilot study of 53 eyes (53 diabetes). Inclusion criteria were previously untreated edema central thickness ≤400 μm (mild edema). Y-MPL IR-MPL treatment was performed a standardized pattern, using both cases the lowest duty...
To present an authoritative, universal, easy-to-use morphologic classification of diabetic maculopathy based on spectral domain optical coherence tomography.The first draft the project was developed previously published classifications and a literature search regarding tomography quantitative qualitative features maculopathy. This sent to international panel retina experts for revision. The met at European School Advanced Studies in Ophthalmology headquarters Lugano, Switzerland, elaborated...
The primary objective of this study was to assess whether the topical administration two neuroprotective drugs (brimonidine and somatostatin) could prevent or arrest retinal neurodysfunction in patients with type 2 diabetes. For purpose, adults aged between 45 75 years a diabetes duration ≥5 an Early Treatment Diabetic Retinopathy Study (ETDRS) level ≤35 were randomly assigned one three arms: placebo, somatostatin, brimonidine. outcome change implicit time (IT) assessed by multifocal...
Treating neovascular age-related macular degeneration with intravitreal aflibercept treat-and-extend (T&E) can reduce treatment burden. ARIES assessed whether early-start T&E was noninferior to late-start T&E.
To evaluate the efficacy of topical 5-fluorouracil (5-FU) alone, without concurrent surgery or radiotherapy, for treatment conjunctival squamous cell carcinoma.Eight patients affected by carcinoma (three recurrent cases, three incompletely excised, and two untreated cases) were treated with 1% 5-FU eye drops. Topical was administered four times daily 4 weeks (one course). Clinical examination (biomicroscopy photography) morphological evaluation cytological specimens used to monitor local...
Purpose. To investigate the effects of subfoveal choroidal neovascularizzation (CNV) secondary to age-related macular degeneration (AMD) on functional parameters quantified with an automatic fundus perimeter. Methods. 118 eyes 98 consecutive patients CNV AMD were evaluated. Best corrected visual acuity (ETDRS charts), photography, and fluorescein angiography performed. Microperimetry (fundus-related perimetry) was used quantify sensitivity fixation pattern (location stability). Results. Of...