A5000964605- Computational Drug Discovery Methods
- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Essential Oils and Antimicrobial Activity
- Synthesis and biological activity
- Natural Antidiabetic Agents Studies
- Microwave-Assisted Synthesis and Applications
- Plant tissue culture and regeneration
- Inflammatory mediators and NSAID effects
- Ecology and Vegetation Dynamics Studies
- Cholinesterase and Neurodegenerative Diseases
- Bioinformatics and Genomic Networks
- Ethnobotanical and Medicinal Plants Studies
- Phytochemical Studies and Bioactivities
- Alzheimer's disease research and treatments
- Metabolomics and Mass Spectrometry Studies
- Botany, Ecology, and Taxonomy Studies
- Carbohydrate Chemistry and Synthesis
- Phytochemicals and Medicinal Plants
- Bioactive natural compounds
- Medicinal Plant Research
- Cholesterol and Lipid Metabolism
- Botanical Research and Applications
- Traditional and Medicinal Uses of Annonaceae
- Psidium guajava Extracts and Applications
Autonomous University of Campeche
2017-2025
University of Quintana Roo
2010-2017
Universidad Autónoma del Estado de Morelos
2005-2012
The mangrove ecosystem is reported to have a large diversity of species that develop in environments with high salinity levels. Plant from mangroves are used traditional medicine and potential sources chemicals entities therapeutic applications. present work aims assess document the influence on antioxidant activity exerted by extracts through spectroscopic chemical analysis. highest recorded Río Verde (RV) Petén Neyac (PN), an LPBR site. leaves Laguncularia racemosa (from RV PN) extraction...
Prostate cancer is the most common in men around world. It a complex and heterogeneous disease which androgens their receptors play crucial role progression development. The current treatment for prostate combination of surgery, hormone therapy, radiation chemotherapy. Therapeutic agents commonly used clinic include steroidal non-steroidal anti-androgens, such as cyproterone acetate, bicalutamide enzalutamide. These few have multiple adverse effects are not 100% effective. Several plant...
Extracts obtained from Cyrtocarpa procera Kunth were evaluated to determine their toxicity on Artemia salina Leach. All the extracts showed a significant activity. Bioguided fractionation of these led isolation β-sitosterol (1) and identification 1,3-propyl-dipentadecanoate (2), 3-hydroxypropyl-9-octadecenoate (3), pentadecylbenzene (4), eicosylbenzene (5), docosane (6), heptacosane (7), dotriacontane (8) 2,6,10-trimethyltetradecane (9) by GC–MS.
Mentha pulegium is common known as "poleo" and used for the treatment of diarrhea, headache cough in Mexican traditional medicine. Organic extracts from aerial parts were evaluated to determine their spasmolytic action on rat isolated ileum test. Hexanic (HEMp), dichloromethanic (DEMp) methanolic (MEMp) induced a concentration-dependent (0.97 1000 μg/mL) antispasmodic effect spontaneous contractions. DEMp was most active extract; therefore, mechanism investigated. This extract (200...
Seven new tetrasaccharide glycosides, tyrianthins 1−7 (1−7), along with six known glycolipids were isolated from the roots of Ipomoea tyrianthina, and their structures elucidated by spectroscopic chemical methods. The content resin glycosides in samples collected three different regions was analyzed compared, results showed that flowering or dry season did not have any effect on composition for same locality, but growing location itself affect glycosides. Intraperitoneal administration to...
The aim was to evaluate the relaxant effect of extracts from Valeriana edulis and determine possible mechanism action hexanic extract as vasorelaxant agent.Extracts rhizomes obtained by maceration (hexanic (HEVe), dichloromethanic (DEVe), methanolic (MEVe) hydroalcoholic (HAEVe) (3.03-500 microg/ml)) were evaluated on aortic rat rings with without endothelium.Extracts induced a significant concentration-dependent endothelium-independent relaxation isolated aorta pre-contracted noradrenaline...
The objective of this study was to describe the diversity, composition, and structure woody vegetation in a section LDF Lerma, Campeche. Between August September 2018, 10 plots × m2 (1 000 total) were delimited, measuring all individuals with diameter at breast height (DBH = 1.30 cm). site described based on relative values density, frequency, dominance (IVI), as well distribution classes. Diversity estimated Shannon-Wiener index (H'), while equity measured by Pielou index. 40 species...
The vasorelaxant effect of methanol extracts (0.86–50 µg/ml) Iresine calea, Psyttacanthus calyculathus. (DC.) G. Don, Laelia autumnalis. (Lex.) Lindley, Brickellia cavanillesii. (Cass.) Gray, and Lepechinia caulescens. (Ortega) Epling, plant species used in Mexican folk medicine for the treatment hypertension related diseases, were evaluated isolated rat aortic rings. I. calea. P. did not show a activity on norepinephrine-evoked contraction (NE, 1 × 10−7.5 M) endothelium-intact (+ E)...
A simple and efficient protocol has been developed in order to obtain healthy seedlings by asymbiotic germination of seeds from Laelia autumnalis. Seeds mature capsules were germinated asymbiotically after being cultured on full- or half-strength Murashige Skoog's (MS) medium, without plant growth regulators with 3.0% 1.5% sucrose. The percentage (% GS) was recorded during 6 weeks using three different conditions incubation: light (80% GS, p < 0.05), darkness (30% white photoperiod (100%...
Se estudió florísticamente la composición y estructura de selva mediana subcaducifolia en dos sitios del área Hobomó, Campeche, México. seleccionaron sitios, cada uno se delimitaron 10 parcelas m2 × (1000 m2) midieron todos los individuos ≥ 1 cm diámetro. El análisis estructural basó valores importancia las especies. La diversidad estimó con el índice Shannon-Wiener (H’). Mediante observaciones recolectas detectaron 79 especies plantas vasculares, pertenecientes a 67 géneros 30 familias. Las...
Enterolobium cyclocarpum and Piscidia piscipula are two important tree Fabaceae species distributed from the Yucatan Peninsula, Mexico. Our aims were focused on E. P. seeds for: (1) to examine seed permeability imbibition rate, (2) evaluate effect of pre-germinative treatments, (3) characterize structures involved presence physical dormancy (PY). We used fresh determine viability by means tetrazolium test, furthermore, we applied mechanical scarification boiler shocks for 5 s, 10 s 15...
In the present study, leaves of Manilkara zapota (L.) P. Royen (Sapotaceae), an evergreen tree recognized for its medicinal properties in Southern Mexico, were used as a model to study effect different drying temperatures on metabolic profile and therefore, antioxidant potential. For this purpose, methanol extraction dried at room temperature (25 °C) or by heat convection (50, 75 100 compared terms efficiency, yield extraction, total phenol content, 1H-NMR profile, DPPH activity. The curves...
The objective of the study was to evaluate antimicrobial activity aqueous and ethanolic Moringa oleifera leaf, stem seed extracts against multidrug-resistant Staphylococcus aureus strains isolated from raw milk in Hidalgo Mexico 2017.The conventional method used identify isolate S. aureus.All isolates were screened for antibiotic sensitivity 12 antibiotics using diskdiffusion method, order select twenty strains.The M. (aqueous ethanolic) tested disk-diffusion agar with penicillin as a...
Coccoloba uvifera is a Mayan medicinal plant, and these leaves are used as antidiarrheal diuretic agents. In the present work, we develop in-vitro, ex-vivo, in-vivo, in-silico strategies to evaluate several aqueous extracts of C. leaves. vitro tests showed that decoction extract (CuDe) presented best yield chlorophyll, phenol, flavonoid content; however, CuDe low antioxidant activity (DPPH model). All exert spasmolytic vasorelaxant in concentration-dependent manner (ex vivo), vivo exerts...
Cecropia obtusifolia bertol is medicinal specie used in the treatment of diabetes mellitus and hypertension it has scientific studies that support traditional use. However, required to understand influence drying temperature on yield pharmacological activity. Drying rate, extraction efficiency, changes UV-Vis spectrum estimating chlorophylls were stimulated with increasing temperature. Finally, relaxant activity vascular smooth muscle increased by 70ºC reducing ability method CARF increases...
The Neurodegenerative diseases have been increasing in the last years. Many of drug candidates to be used treatment neurodegenerative disease present specific 3D structural features. One important protein this sense is acetylcholinesterase (AChE); which target many Alzheimer\'s dementia drugs. Consequently, prediction Drug-Proteins Interactions (DPIs/nDPIs) between new with structure and targets it about major importance. For it, we can use Quantitative Structure-Activity Relationships...