A5091031886- Osteoarthritis Treatment and Mechanisms
- Bone Tissue Engineering Materials
- Biosensors and Analytical Detection
- Advanced biosensing and bioanalysis techniques
- 3D Printing in Biomedical Research
- Mesenchymal stem cell research
- Electrospun Nanofibers in Biomedical Applications
- Orthopaedic implants and arthroplasty
- Cellular Mechanics and Interactions
- Dental materials and restorations
- Tissue Engineering and Regenerative Medicine
- Knee injuries and reconstruction techniques
- biodegradable polymer synthesis and properties
- Silk-based biomaterials and applications
- SARS-CoV-2 detection and testing
- Total Knee Arthroplasty Outcomes
- Advanced Biosensing Techniques and Applications
- Photoacoustic and Ultrasonic Imaging
- Dental Implant Techniques and Outcomes
- Tendon Structure and Treatment
- Infrared Thermography in Medicine
- Lubricants and Their Additives
- Proteoglycans and glycosaminoglycans research
- Corneal Surgery and Treatments
- Tribology and Lubrication Engineering
University of Malaya
2013-2023
University of Kuala Lumpur
2011-2021
Faculty (United Kingdom)
2015-2016
Engineering (Italy)
2015-2016
Hospital Kuala Lumpur
2015-2016
Xi'an Jiaotong University
2016
Queen Mary University of London
2005
An integrated paper-based sample-to-answer biosensor is proposed, which enables simple nucleic acid extraction, amplification and detection for point-of-care testing.
Point-of-care (POC) diagnostics is playing an increasingly important role in public health, environmental monitoring, and food safety analysis. Smartphones, alone or conjunction with add-on devices, have shown great capability of data collection, analysis, display, transmission, making them popular POC diagnostics. In this article, the state-of-the-art advances smartphone-based diagnostic technologies their applications past few years are outlined, ranging from <italic...
Paper has recently attracted increasing attention as a substrate for various biomedical applications. By modifying its physical and chemical properties, paper can be used an alternative to conventional cell culture substrates. Because it stacked into three-dimensional (3D) structure, which better mimic the in vivo microenvironment. shown great potential 3D platform developing normal diseased models. This gives precise control over extracellular matrix (ECM) composition well distribution...
In nucleic acid testing (NAT), gold nanoparticle (AuNP)-based lateral flow assays (LFAs) have received significant attention due to their cost-effectiveness, rapidity, and the ability produce a simple colorimetric readout. However, poor sensitivity of AuNP-based LFAs limits its widespread applications. Even though various efforts been made improve assay sensitivity, most methods are inappropriate for integration into LFA sample-to-answer NAT at point-of-care (POC), usually complicated...
Abstract Cryopreservation represents an effective technique to maintain the functional properties of human adipose-derived stem cells (ASCs) and allows pooling via long-term storage for clinical applications, e.g. , cell-based therapies. It is crucial reduce freezing injury during cryopreservation process by loading ASCs with optimum concentration suitable cryoprotective agents (CPAs). In this study, were preserved 3 months in different combinations CPAs, including 1) 0.25 M trehalose; 2) 5%...
Paper-based devices have been broadly used for the point-of-care detection of dengue viral nucleic acids due to their simplicity, cost-effectiveness, and readily observable colorimetric readout. However, moderate sensitivity functionality limited applications. Despite above-mentioned advantages, paper substrates are lacking in ability control fluid flow, contrast flow enabled by polymer (e.g., agarose) with tunable pore size porosity. Herein, taking benefits from both materials, authors...
The emerging demand for cost‐effective, easily accessible, and rapid prototyping electronics fabrication calls novel techniques to design manufacture electronic components devices wearable functional sensing, on‐skin medical monitoring, body‐worn energy conversion. Inspired by daily hand‐writing, innovative ubiquitously available pens can be employed write conductive patterns on multiple substrates; such a low‐cost, fast, user‐friendly direct writing paradigm has recently aroused remarkable...
An integrated LFA is developed to perform isothermal amplification and detection at the point-of-care.
The growth of global food demand combined with the increased appeal to access different foods from every corner globe is forcing industry look for alternative technologies increase shelf life. Essential oils (EOs) as naturally occurring functional ingredients have shown great prospects in active packaging. EOs can inhibit superficial pathogens, modify nutritious values without affecting sensory qualities food, and prolong life when used packaging an ingredient. Since 2016, various reports...
A simple strategy to fabricate paper-based electrochemical devices has been developed by directly writing using a pressure-assisted ball pen.
Electrospun polycaprolactone (PCL) nanofibers have emerged as a promising material in diverse biomedical applications due to their various favorable features. However, application the field of biosensors such point-of-care lateral flow assays (LFA) has not been investigated. The present study demonstrates use electrospun PCL reaction membrane for LFA. were treated with NaOH solution different concentrations and durations achieve desirable rate optimum detection sensitivity nucleic acid-based...
Extracellular environments can regulate cell behavior because cells actively sense their mechanical environments. This study evaluated the adhesion, proliferation and morphology of endothelial on polydimethylsiloxane (PDMS)/alumina (Al2O3) composites pure PDMS. The substrates were prepared from PDMS its with 2.5, 5, 7.5, 10 wt % Al2O3 at a curing temperature 50°C for 4 h. then characterized by mechanical, structural, morphological analyses. proliferation, cultured bovine aortic (BAEC)...